Project name: 4ioi:A

Chain sequence(s)	A: DIQMTQSSPILLLSSASVGDRRVTITCCRASQDVNTAVAWYQQRTNGSPRLLIYSASFLYSGVPSRFSGSSRSGTDFTTLLTISSLQPEDIADYYCQQHYTTPPTFGAGTKKVEIKRTVAAPSVFIFPPSDEQLKSSGTASVVVCLLNNFYPREAKKVQWKVDNALQSSGNSQESVVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACCEVTHQGLSSPVTKSFNRGEC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.4388
• Maximal score value: 2.5688
• Average score: -0.6969
• Total score value: -149.1269

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	A	-2.2965
2	I	A	0.0000
3	Q	A	-1.9033
4	M	A	0.0000
5	T	A	-0.9734
6	Q	A	0.0000
7	S	A	0.4332
8	P	A	1.2844
9	I	A	2.5688
10	L	A	2.2946
11	L	A	1.1370
12	S	A	-0.1294
13	A	A	0.0000
14	S	A	-0.7149
15	V	A	0.1532
16	G	A	-0.6169
17	D	A	-1.6258
18	R	A	-2.2705
19	V	A	0.0000
20	T	A	-0.5949
21	I	A	0.0000
22	T	A	-0.5203
23	C	A	0.0000
24	R	A	-2.8565
25	A	A	0.0000
26	S	A	-2.2271
27	Q	A	-2.8501
28	D	A	-2.6587
29	V	A	0.0000
30	N	A	-1.8034
31	T	A	-0.9329
32	A	A	-0.4897
33	V	A	0.0000
34	A	A	0.8175
35	W	A	0.0000
36	Y	A	-0.2422
37	Q	A	0.0000
38	Q	A	-1.7637
39	R	A	-2.3446
40	T	A	-1.8866
41	N	A	-1.9715
42	G	A	-1.7315
43	S	A	-1.3947
44	P	A	-1.5715
45	R	A	-1.8844
46	L	A	-0.1829
47	L	A	0.0000
48	I	A	0.0000
49	Y	A	1.6210
50	S	A	0.5026
51	A	A	0.0000
52	S	A	0.9324
53	F	A	2.5028
54	L	A	1.9426
55	Y	A	1.5320
56	S	A	0.4578
57	G	A	-0.2090
58	V	A	-0.0225
59	P	A	-0.1964
60	S	A	-0.3076
61	R	A	-0.7300
62	F	A	0.0000
63	S	A	0.0755
64	G	A	0.1499
65	S	A	-0.4775
66	R	A	-1.5602
67	S	A	-1.3378
68	G	A	-1.8131
69	T	A	-2.2397
70	D	A	-2.0754
71	F	A	0.0000
72	T	A	-0.7492
73	L	A	0.0000
74	T	A	-0.6211
75	I	A	0.0000
76	S	A	-1.3643
77	S	A	-1.0791
78	L	A	0.0000
79	Q	A	-0.7638
80	P	A	-1.4780
81	E	A	-1.9526
82	D	A	0.0000
83	I	A	-1.2133
84	A	A	0.0000
85	D	A	-0.4918
86	Y	A	0.0000
87	Y	A	0.2285
88	C	A	0.0000
89	Q	A	0.0000
90	Q	A	0.0000
91	H	A	-0.4715
92	Y	A	0.0982
93	T	A	-0.3849
94	T	A	-0.5318
95	P	A	-0.6213
96	P	A	-0.4364
97	T	A	0.0190
98	F	A	1.2922
99	G	A	0.3060
100	A	A	0.5624
101	G	A	0.0000
102	T	A	0.0000
103	K	A	0.4432
104	V	A	0.0000
105	E	A	-0.8279
106	I	A	0.0000
107	K	A	-1.2562
108	R	A	-0.8706
109	T	A	-0.1624
110	V	A	0.1882
111	A	A	-0.2443
112	A	A	-0.2740
113	P	A	0.0000
114	S	A	-0.0219
115	V	A	0.4444
116	F	A	1.4149
117	I	A	1.2794
118	F	A	1.4819
119	P	A	0.0453
120	P	A	0.0000
121	S	A	-1.7600
122	D	A	-3.1946
123	E	A	-3.3754
124	Q	A	-2.4907
125	L	A	-2.5085
126	K	A	-2.9941
127	S	A	-1.8810
128	G	A	-1.2362
129	T	A	-0.9346
130	A	A	0.0000
131	S	A	0.0430
132	V	A	0.0000
133	V	A	0.7737
134	C	A	0.0000
135	L	A	0.5341
136	L	A	0.0000
137	N	A	-0.6080
138	N	A	-1.6272
139	F	A	0.0000
140	Y	A	0.0000
141	P	A	-1.8681
142	R	A	-3.2150
143	E	A	-3.2849
144	A	A	-2.3878
145	K	A	-2.4949
146	V	A	-1.1202
147	Q	A	-0.7112
148	W	A	0.0000
149	K	A	-0.6598
150	V	A	0.0000
151	D	A	-1.9937
152	N	A	-1.5869
153	A	A	-0.3818
154	L	A	0.4658
155	Q	A	-0.4720
156	S	A	-0.6593
157	G	A	-1.2889
158	N	A	-1.5498
159	S	A	-1.6512
160	Q	A	-2.3204
161	E	A	-2.1660
162	S	A	-1.2821
163	V	A	-0.8321
164	T	A	-1.3021
165	E	A	-2.5062
166	Q	A	0.0000
167	D	A	-2.5942
168	S	A	-2.5117
169	K	A	-2.8032
170	D	A	-2.3748
171	S	A	0.0000
172	T	A	0.0000
173	Y	A	0.0000
174	S	A	-1.1409
175	L	A	0.0000
176	S	A	-0.4139
177	S	A	0.0000
178	T	A	-0.6515
179	L	A	0.0000
180	T	A	-0.6208
181	L	A	-0.6722
182	S	A	-1.1373
183	K	A	-2.0773
184	A	A	-1.7331
185	D	A	-2.2022
186	Y	A	0.0000
187	E	A	-3.2475
188	K	A	-3.4388
189	H	A	-2.9093
190	K	A	-3.3136
191	V	A	-1.6174
192	Y	A	0.0000
193	A	A	0.0000
194	C	A	0.0000
195	E	A	-0.9090
196	V	A	0.0000
197	T	A	-1.2385
198	H	A	0.0000
199	Q	A	-1.8262
200	G	A	-0.5053
201	L	A	-0.2093
202	S	A	-0.4268
203	S	A	-0.4034
204	P	A	-0.5076
205	V	A	0.1313
206	T	A	-0.3369
207	K	A	-0.3919
208	S	A	-0.3784
209	F	A	0.0000
210	N	A	-2.0244
211	R	A	-2.4926
212	G	A	-2.0015
213	E	A	-2.1887
214	C	A	-0.4153