| Chain sequence(s) |
A: DIQMTQSPSSLSASVGDRVTITCRASQSISNWLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSFPWTFGQGTKVEIK B: EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAIYGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKLSILGYQEAFDIWGQGTLVTVSS |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | E | B | -1.8968 | |
| 2 | V | B | -0.7776 | |
| 3 | Q | B | -1.1575 | |
| 4 | L | B | 0.0000 | |
| 5 | V | B | 0.7499 | |
| 6 | E | B | 0.0000 | |
| 7 | S | B | -0.2843 | |
| 8 | G | B | -0.7369 | |
| 9 | G | B | -0.0090 | |
| 10 | G | B | 0.7365 | |
| 11 | L | B | 1.3245 | |
| 12 | V | B | 0.0000 | |
| 13 | Q | B | -1.3457 | |
| 14 | P | B | -1.5549 | |
| 15 | G | B | -1.4227 | |
| 16 | G | B | -1.1133 | |
| 17 | S | B | -1.2946 | |
| 18 | L | B | -1.1776 | |
| 19 | R | B | -1.9707 | |
| 20 | L | B | 0.0000 | |
| 21 | S | B | -0.4171 | |
| 22 | C | B | 0.0000 | |
| 23 | A | B | -0.0919 | |
| 24 | A | B | 0.0000 | |
| 25 | S | B | -0.8242 | |
| 26 | G | B | -0.7973 | |
| 27 | F | B | -0.1126 | |
| 28 | T | B | -0.1931 | |
| 29 | F | B | 0.0000 | |
| 30 | S | B | -0.6073 | |
| 31 | S | B | 0.4312 | |
| 32 | Y | B | 0.8679 | |
| 33 | A | B | 0.0000 | |
| 34 | M | B | 0.0000 | |
| 35 | S | B | 0.0000 | |
| 36 | W | B | 0.0000 | |
| 37 | V | B | 0.0000 | |
| 38 | R | B | -0.6768 | |
| 39 | Q | B | -1.1719 | |
| 40 | A | B | -1.2590 | |
| 41 | P | B | -0.9790 | |
| 42 | G | B | -1.6149 | |
| 43 | K | B | -2.5328 | |
| 44 | G | B | 0.0000 | |
| 45 | L | B | 0.0000 | |
| 46 | E | B | -1.4791 | |
| 47 | W | B | 0.0000 | |
| 48 | V | B | 0.0000 | |
| 49 | S | B | 0.0000 | |
| 50 | A | B | 0.4993 | |
| 51 | I | B | 0.0000 | |
| 52 | Y | B | 0.3423 | |
| 53 | G | B | 0.0000 | |
| 54 | S | B | -0.6711 | |
| 55 | G | B | -1.0458 | |
| 56 | G | B | -0.7724 | |
| 57 | S | B | -0.1838 | |
| 58 | T | B | 0.4476 | |
| 59 | Y | B | 1.2015 | |
| 60 | Y | B | -0.0303 | |
| 61 | A | B | -1.1904 | |
| 62 | D | B | -2.5101 | |
| 63 | S | B | -1.8627 | |
| 64 | V | B | 0.0000 | |
| 65 | K | B | -2.5730 | |
| 66 | G | B | -2.5701 | |
| 67 | R | B | -2.8776 | |
| 68 | F | B | -1.8005 | |
| 69 | T | B | -1.3736 | |
| 70 | I | B | 0.0000 | |
| 71 | S | B | -0.6248 | |
| 72 | R | B | -1.1636 | |
| 73 | D | B | -2.0328 | |
| 74 | N | B | -2.5155 | |
| 75 | S | B | -1.9988 | |
| 76 | K | B | -2.6431 | |
| 77 | N | B | -2.1536 | |
| 78 | T | B | -1.2014 | |
| 79 | L | B | 0.0000 | |
| 80 | Y | B | -0.7137 | |
| 81 | L | B | 0.0000 | |
| 82 | Q | B | -1.9160 | |
| 83 | M | B | 0.0000 | |
| 84 | N | B | -2.2413 | |
| 85 | S | B | -1.6524 | |
| 86 | L | B | 0.0000 | |
| 87 | R | B | -2.0618 | |
| 88 | A | B | -1.6261 | |
| 89 | E | B | -2.1603 | |
| 90 | D | B | 0.0000 | |
| 91 | T | B | -0.5973 | |
| 92 | A | B | 0.0000 | |
| 93 | V | B | 0.3359 | |
| 94 | Y | B | 0.0000 | |
| 95 | Y | B | 0.0000 | |
| 96 | C | B | 0.0000 | |
| 97 | A | B | 0.0000 | |
| 98 | K | B | -0.2547 | |
| 99 | L | B | 0.0000 | |
| 100 | S | B | 0.6664 | |
| 101 | I | B | 1.6070 | |
| 102 | L | B | 1.8559 | |
| 103 | G | B | 0.6047 | |
| 104 | Y | B | 0.7105 | |
| 105 | Q | B | -0.2983 | |
| 106 | E | B | -0.4417 | |
| 107 | A | B | 0.0000 | |
| 108 | F | B | 0.0000 | |
| 109 | D | B | -1.6253 | |
| 110 | I | B | -0.6698 | |
| 111 | W | B | 0.0000 | |
| 112 | G | B | -0.7441 | |
| 113 | Q | B | -1.3901 | |
| 114 | G | B | -0.3519 | |
| 115 | T | B | 0.4514 | |
| 116 | L | B | 1.5050 | |
| 117 | V | B | 0.0000 | |
| 118 | T | B | 0.6086 | |
| 119 | V | B | 0.0000 | |
| 120 | S | B | -0.7199 | |
| 121 | S | B | -0.5611 | |
| 1 | D | A | -2.0577 | |
| 2 | I | A | 0.0000 | |
| 3 | Q | A | -2.0371 | |
| 4 | M | A | 0.0000 | |
| 5 | T | A | -1.4146 | |
| 6 | Q | A | -1.4348 | |
| 7 | S | A | -0.8600 | |
| 8 | P | A | -0.6422 | |
| 9 | S | A | -0.9490 | |
| 10 | S | A | -1.0344 | |
| 11 | L | A | -0.6201 | |
| 12 | S | A | -0.9889 | |
| 13 | A | A | 0.0000 | |
| 14 | S | A | -0.6142 | |
| 15 | V | A | 0.3593 | |
| 16 | G | A | -0.6333 | |
| 17 | D | A | -1.5816 | |
| 18 | R | A | -2.1798 | |
| 19 | V | A | -1.0889 | |
| 20 | T | A | -0.5481 | |
| 21 | I | A | 0.0000 | |
| 22 | T | A | -0.9863 | |
| 23 | C | A | 0.0000 | |
| 24 | R | A | -2.5836 | |
| 25 | A | A | -1.7154 | |
| 26 | S | A | -1.5139 | |
| 27 | Q | A | -1.1551 | |
| 28 | S | A | -0.9157 | |
| 29 | I | A | -0.1382 | |
| 30 | S | A | -0.3916 | |
| 31 | N | A | -1.1680 | |
| 32 | W | A | -0.2437 | |
| 33 | L | A | 0.0000 | |
| 34 | N | A | 0.0000 | |
| 35 | W | A | 0.0000 | |
| 36 | Y | A | 0.0000 | |
| 37 | Q | A | 0.0000 | |
| 38 | Q | A | 0.0000 | |
| 39 | K | A | -1.2498 | |
| 40 | P | A | -1.1041 | |
| 41 | G | A | -1.6764 | |
| 42 | K | A | -2.4969 | |
| 43 | A | A | -1.6595 | |
| 44 | P | A | 0.0000 | |
| 45 | K | A | -1.3523 | |
| 46 | L | A | 0.0000 | |
| 47 | L | A | 0.0000 | |
| 48 | I | A | 0.0000 | |
| 49 | Y | A | 0.2086 | |
| 50 | A | A | -0.2290 | |
| 51 | A | A | -0.3127 | |
| 52 | S | A | -0.2777 | |
| 53 | S | A | 0.1715 | |
| 54 | L | A | 0.5578 | |
| 55 | Q | A | -0.2163 | |
| 56 | S | A | -0.3485 | |
| 57 | G | A | -0.4931 | |
| 58 | V | A | -0.2508 | |
| 59 | P | A | -0.2939 | |
| 60 | S | A | -0.3663 | |
| 61 | R | A | -0.6316 | |
| 62 | F | A | 0.0000 | |
| 63 | S | A | -0.2397 | |
| 64 | G | A | -0.2500 | |
| 65 | S | A | -0.7312 | |
| 66 | G | A | -1.0733 | |
| 67 | S | A | -1.0250 | |
| 68 | G | A | -1.1307 | |
| 69 | T | A | -1.4397 | |
| 70 | D | A | -1.8344 | |
| 71 | F | A | 0.0000 | |
| 72 | T | A | -0.6589 | |
| 73 | L | A | 0.0000 | |
| 74 | T | A | -0.6407 | |
| 75 | I | A | 0.0000 | |
| 76 | S | A | -1.3198 | |
| 77 | S | A | -1.0605 | |
| 78 | L | A | 0.0000 | |
| 79 | Q | A | -0.7851 | |
| 80 | P | A | -0.9668 | |
| 81 | E | A | -1.5555 | |
| 82 | D | A | 0.0000 | |
| 83 | F | A | -0.3814 | |
| 84 | A | A | 0.0000 | |
| 85 | T | A | -0.5769 | |
| 86 | Y | A | 0.0000 | |
| 87 | Y | A | 0.0000 | |
| 88 | C | A | 0.0000 | |
| 89 | Q | A | 0.0000 | |
| 90 | Q | A | 0.0000 | |
| 91 | S | A | 0.7285 | |
| 92 | Y | A | 1.1919 | |
| 93 | S | A | 0.8040 | |
| 94 | F | A | 0.8557 | |
| 95 | P | A | 0.4055 | |
| 96 | W | A | -0.0300 | |
| 97 | T | A | -0.6852 | |
| 98 | F | A | 0.0000 | |
| 99 | G | A | -1.5582 | |
| 100 | Q | A | -2.1878 | |
| 101 | G | A | -1.6638 | |
| 102 | T | A | 0.0000 | |
| 103 | K | A | -1.6481 | |
| 104 | V | A | 0.0000 | |
| 105 | E | A | -1.4996 | |
| 106 | I | A | -0.9337 | |
| 107 | K | A | -1.4015 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine