Project name: hr2.nt96

Chain sequence(s)	A: KEIREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLMSLTDDQALAANEELTIKIKCDKEKNMLHITDTGIGMTKEELVKNLGTIAKSGTSEFLSKLTEAQEDGQSTSELIGQFGVGFYSAFLVADRVIVTSKHNNDTQHIWESDSNEFFVTDDPRGDTLGRGSTITLVLKEEATDYLELETVKNLVRKYSQFINFPIYVWSS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.018
• Maximal score value: 1.4113
• Average score: -1.057
• Total score value: -230.4295

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
689	K	A	-2.4538
690	E	A	-2.6204
691	I	A	-0.9338
692	R	A	-2.9802
693	E	A	-4.0180
694	K	A	-3.8398
695	S	A	-3.0299
696	E	A	-2.7737
697	K	A	-2.0792
698	F	A	-0.7702
699	A	A	-0.6194
700	F	A	0.0000
701	Q	A	-1.0704
702	A	A	-1.4797
703	E	A	-2.1299
704	V	A	0.0000
705	N	A	0.0000
706	R	A	-2.9325
707	M	A	0.0000
708	M	A	0.0000
709	K	A	-2.7055
710	L	A	-0.9615
711	I	A	0.0000
712	I	A	-0.9844
713	N	A	-1.0301
714	S	A	-0.1379
715	L	A	0.8906
716	Y	A	-0.2843
717	K	A	-1.4695
718	N	A	-1.2346
719	K	A	-0.9391
720	E	A	-1.1174
721	I	A	0.0000
722	F	A	0.0000
723	L	A	0.0000
724	R	A	-1.1477
725	E	A	0.0000
726	L	A	0.0000
727	I	A	0.0000
728	S	A	-1.1186
729	N	A	-2.0383
730	A	A	0.0000
731	S	A	-1.9323
732	D	A	-3.1856
733	A	A	-2.0196
734	L	A	0.0000
735	D	A	-2.9098
736	K	A	-2.4211
737	I	A	0.0000
738	R	A	-1.3393
739	L	A	0.6233
740	M	A	0.0037
741	S	A	0.0000
742	L	A	1.0400
743	T	A	-0.0594
744	D	A	-1.4934
745	D	A	-2.6484
746	Q	A	-2.2824
747	A	A	0.0000
748	L	A	-1.9524
749	A	A	-1.3729
750	A	A	-0.9734
751	N	A	-1.6270
752	E	A	-3.0217
753	E	A	-2.6209
754	L	A	-1.5243
755	T	A	0.0000
756	I	A	0.0000
757	K	A	-0.0201
758	I	A	0.0000
759	K	A	-0.0868
760	C	A	-1.0980
761	D	A	-2.4174
762	K	A	-3.5768
763	E	A	-3.7134
764	K	A	-3.4079
765	N	A	-2.8979
766	M	A	-1.5557
767	L	A	0.0000
768	H	A	-0.3385
769	I	A	0.0000
770	T	A	-0.1722
771	D	A	0.0000
772	T	A	0.0000
773	G	A	0.0000
774	I	A	-0.6323
775	G	A	0.0000
776	M	A	-0.8877
777	T	A	-1.7148
778	K	A	-2.3884
779	E	A	-3.0141
780	E	A	-2.4119
781	L	A	0.0000
782	V	A	0.0000
783	K	A	-1.8256
784	N	A	-1.1945
785	L	A	0.0000
786	G	A	0.0000
787	T	A	-0.2090
788	I	A	0.8828
789	A	A	-0.1929
790	K	A	-1.1320
791	S	A	-0.8805
792	G	A	-0.8608
793	T	A	0.0000
794	S	A	0.0000
795	E	A	-1.8980
796	F	A	0.0000
797	L	A	0.0000
798	S	A	-2.5412
799	K	A	-2.7116
800	L	A	-1.6808
801	T	A	-1.8740
802	E	A	-2.9843
803	A	A	0.0000
804	Q	A	-2.7066
805	E	A	-3.5445
806	D	A	-3.7186
807	G	A	-2.4856
808	Q	A	0.0000
809	S	A	-1.1781
810	T	A	0.0000
811	S	A	0.0000
812	E	A	-1.2260
813	L	A	-0.9708
814	I	A	0.0000
815	G	A	-1.2992
816	Q	A	-1.4409
817	F	A	-0.7773
818	G	A	-0.7866
819	V	A	0.0000
820	G	A	-0.8111
821	F	A	0.0000
822	Y	A	0.0000
823	S	A	0.0000
824	A	A	0.0000
825	F	A	0.0000
826	L	A	0.0000
827	V	A	0.0000
828	A	A	0.0000
829	D	A	-2.5343
830	R	A	-2.0286
831	V	A	0.0000
832	I	A	-0.0346
833	V	A	0.0000
834	T	A	-0.1590
835	S	A	0.0000
836	K	A	-0.5345
837	H	A	-0.8988
838	N	A	-1.0171
839	N	A	-1.6862
840	D	A	-1.3853
841	T	A	-1.1330
842	Q	A	0.0000
843	H	A	-1.2603
844	I	A	-0.7026
845	W	A	0.0000
846	E	A	-0.8219
847	S	A	0.0000
848	D	A	-2.0908
849	S	A	-2.4219
850	N	A	-2.4938
851	E	A	-2.7206
852	F	A	-1.1878
853	F	A	0.0000
854	V	A	-0.9423
855	T	A	0.0000
856	D	A	-2.8734
857	D	A	-3.2950
858	P	A	-2.5278
859	R	A	-3.1817
860	G	A	-2.3812
861	D	A	-2.3673
862	T	A	-1.1900
863	L	A	-0.2275
864	G	A	-0.2978
865	R	A	0.0000
866	G	A	0.0000
867	S	A	0.0617
868	T	A	0.0047
869	I	A	0.0000
870	T	A	0.0000
871	L	A	0.0000
872	V	A	-1.2570
873	L	A	0.0000
874	K	A	-2.3400
875	E	A	-3.3055
876	E	A	-3.0535
877	A	A	0.0000
878	T	A	-2.4710
879	D	A	-2.7757
880	Y	A	-1.8454
881	L	A	0.0000
882	E	A	-2.4110
883	L	A	-1.3911
884	E	A	-2.6679
885	T	A	-2.0303
886	V	A	0.0000
887	K	A	-2.7289
888	N	A	-2.5393
889	L	A	0.0000
890	V	A	-1.6287
891	R	A	-3.1045
892	K	A	-2.7417
893	Y	A	-1.0449
894	S	A	0.0000
895	Q	A	-1.4233
896	F	A	0.8782
897	I	A	0.3046
898	N	A	-0.7296
899	F	A	-0.2636
900	P	A	0.0676
901	I	A	0.5968
902	Y	A	1.4113
903	V	A	1.0673
904	W	A	1.2473
905	S	A	0.3233
906	S	A	-0.1366