Project name: 5iop:A

Chain sequence(s)	A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADDYEKHKVYACEVTHQGLSSPVTKSFNRGA
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.5404
• Maximal score value: 2.2137
• Average score: -0.8133
• Total score value: -173.228

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	A	-1.4485
2	I	A	0.0000
3	L	A	0.7138
4	L	A	0.0000
5	T	A	-0.2820
6	Q	A	-0.0021
7	S	A	0.2019
8	P	A	1.0224
9	V	A	2.2137
10	I	A	1.9902
11	L	A	0.9048
12	S	A	-0.2051
13	V	A	-1.2715
14	S	A	-1.7480
15	P	A	-1.8344
16	G	A	-2.1209
17	E	A	-2.9120
18	R	A	-3.2706
19	V	A	0.0000
20	S	A	-0.7636
21	F	A	0.0000
22	S	A	-0.7526
23	C	A	0.0000
24	R	A	-2.5240
25	A	A	-1.4280
26	S	A	-1.1410
27	Q	A	-1.8727
28	S	A	-1.7084
29	I	A	0.0000
30	G	A	-1.1509
31	T	A	-0.7914
32	N	A	-1.1022
33	I	A	0.0000
34	H	A	-0.2739
35	W	A	0.0000
36	Y	A	-0.0438
37	Q	A	0.0000
38	Q	A	-1.3927
39	R	A	-1.9613
40	T	A	-1.7549
41	N	A	-1.7343
42	G	A	-1.4771
43	S	A	-1.0678
44	P	A	-0.9986
45	R	A	-0.7932
46	L	A	-0.1063
47	L	A	0.0000
48	I	A	0.0000
49	K	A	-0.7994
50	Y	A	-0.1851
51	A	A	0.0000
52	S	A	-1.1189
53	E	A	-1.8564
54	S	A	-1.0857
55	I	A	-0.5206
56	S	A	-0.2712
57	G	A	-0.4549
58	I	A	-0.1796
59	P	A	-0.3217
60	S	A	-0.5641
61	R	A	-1.0925
62	F	A	0.0000
63	S	A	-0.8319
64	G	A	-0.6784
65	S	A	-0.7344
66	G	A	-1.0044
67	S	A	-1.0646
68	G	A	-1.4017
69	T	A	-1.9549
70	D	A	-2.4863
71	F	A	0.0000
72	T	A	-0.8670
73	L	A	0.0000
74	S	A	-0.9029
75	I	A	0.0000
76	N	A	-2.5364
77	S	A	-2.3042
78	V	A	0.0000
79	E	A	-2.2771
80	S	A	-2.0951
81	E	A	-1.8998
82	D	A	0.0000
83	I	A	-1.3853
84	A	A	0.0000
85	D	A	-0.4464
86	Y	A	0.0000
87	Y	A	0.2248
88	C	A	0.0000
89	Q	A	0.2497
90	Q	A	0.0000
91	N	A	-1.4529
92	N	A	-1.9027
93	N	A	-1.4434
94	W	A	-0.0033
95	P	A	-0.1805
96	T	A	-0.5122
97	T	A	0.2983
98	F	A	1.4418
99	G	A	0.6468
100	A	A	0.6692
101	G	A	0.0000
102	T	A	0.0000
103	K	A	0.2665
104	L	A	0.0000
105	E	A	-0.9030
106	L	A	0.0000
107	K	A	-1.6502
108	R	A	-1.1739
109	T	A	-0.1431
110	V	A	0.2712
111	A	A	0.0640
112	A	A	-0.1793
113	P	A	0.0000
114	S	A	-0.1214
115	V	A	0.0000
116	F	A	1.2765
117	I	A	1.3298
118	F	A	1.6513
119	P	A	0.1168
120	P	A	-0.6946
121	S	A	-1.7766
122	D	A	-3.2187
123	E	A	-3.4180
124	Q	A	-2.4688
125	L	A	-2.5560
126	K	A	-3.0209
127	S	A	-1.8983
128	G	A	-1.3786
129	T	A	-1.2045
130	A	A	0.0000
131	S	A	0.0605
132	V	A	0.0000
133	V	A	0.7873
134	C	A	0.0000
135	L	A	0.5566
136	L	A	0.0000
137	N	A	-0.5804
138	N	A	-1.2552
139	F	A	0.0000
140	Y	A	-1.2103
141	P	A	-1.7095
142	R	A	-2.8526
143	E	A	-3.1662
144	A	A	-2.2189
145	K	A	-2.0804
146	V	A	-1.1602
147	Q	A	-1.0937
148	W	A	0.0000
149	K	A	-1.2240
150	V	A	0.0000
151	D	A	-2.0877
152	N	A	-1.7543
153	A	A	-0.5938
154	L	A	0.1434
155	Q	A	-0.4585
156	S	A	-0.5595
157	G	A	-1.0198
158	N	A	-0.9896
159	S	A	-1.3700
160	Q	A	-2.1889
161	E	A	-2.1143
162	S	A	-1.2475
163	V	A	-0.7784
164	T	A	-1.2559
165	E	A	-2.3061
166	Q	A	0.0000
167	D	A	-2.2223
168	S	A	-2.2686
169	K	A	-2.6626
170	D	A	-2.0724
171	S	A	0.0000
172	T	A	0.0000
173	Y	A	0.0000
174	S	A	-0.9892
175	L	A	0.0000
176	S	A	-0.4034
177	S	A	0.0000
178	T	A	-0.5276
179	L	A	0.0000
180	T	A	-0.4084
181	L	A	-0.6980
182	S	A	-1.1459
183	K	A	-2.1956
184	A	A	-1.9357
185	D	A	-2.6753
186	Y	A	0.0000
187	E	A	-3.2575
188	K	A	-3.5404
189	H	A	-2.9025
190	K	A	-2.9137
191	V	A	-1.2897
192	Y	A	0.0000
193	A	A	-1.0440
194	C	A	0.0000
195	E	A	-1.4747
196	V	A	0.0000
197	T	A	-1.2828
198	H	A	0.0000
199	Q	A	-1.5425
200	G	A	-0.3829
201	L	A	-0.1398
202	S	A	-0.3990
203	S	A	-0.3770
204	P	A	-0.5830
205	V	A	-0.1562
206	T	A	-0.5676
207	K	A	-0.4177
208	S	A	-0.3384
209	F	A	-0.3861
210	N	A	-1.4185
211	R	A	-1.9625
212	G	A	-1.2657
213	A	A	-0.6508