Project name: 5ggs:A

Chain sequence(s)	A: VQLVQSGVEVKKPGASVKVSCKASGYTFTNYYMYWVRQAPGQGLEWMGGINPSNGGTNFNEKFKNRVTLTTDSSTTTAYMELKSLQFDDTAVYYCARRDYRFDMGFDYWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.5356
• Maximal score value: 2.5393
• Average score: -0.5257
• Total score value: -115.1327

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	V	A	1.4907
3	Q	A	-0.4473
4	L	A	0.0000
5	V	A	-0.3599
6	Q	A	0.0000
7	S	A	-0.4419
8	G	A	0.1912
9	V	A	1.5311
10	E	A	0.3871
11	V	A	0.4030
12	K	A	-0.8381
13	K	A	-1.5309
14	P	A	-1.3761
15	G	A	-1.2566
16	A	A	-1.2537
17	S	A	-1.5964
18	V	A	0.0000
19	K	A	-2.0947
20	V	A	0.0000
21	S	A	-0.7607
22	C	A	0.0000
23	K	A	-1.7673
24	A	A	-0.6466
25	S	A	-0.1728
26	G	A	0.0306
27	Y	A	1.1850
28	T	A	0.0000
29	F	A	0.0000
30	T	A	0.0720
31	N	A	-0.3125
32	Y	A	0.0000
33	Y	A	0.0367
34	M	A	0.0000
35	Y	A	0.2413
36	W	A	0.0000
37	V	A	0.0000
38	R	A	-0.1297
39	Q	A	-0.4607
40	A	A	-1.0066
41	P	A	-1.1666
42	G	A	-1.3353
43	Q	A	-1.6012
44	G	A	-0.7272
45	L	A	0.6671
46	E	A	-0.1950
47	W	A	0.1528
48	M	A	0.0000
49	G	A	0.0000
50	G	A	0.0000
51	I	A	0.0000
52	N	A	-0.9351
53	P	A	-0.9227
54	S	A	-1.1393
55	N	A	-1.7494
56	G	A	-1.4023
57	G	A	-1.2334
58	T	A	-1.0157
59	N	A	-1.6957
60	F	A	-1.7537
61	N	A	-2.2267
62	E	A	-3.5356
63	K	A	-3.2701
64	F	A	0.0000
65	K	A	-3.4709
66	N	A	-2.9116
67	R	A	-2.0689
68	V	A	0.0000
69	T	A	-1.0135
70	L	A	0.0000
71	T	A	-0.3992
72	T	A	-0.9594
73	D	A	-1.2104
74	S	A	-1.0305
75	S	A	-0.6582
76	T	A	-0.8523
77	T	A	-0.8645
78	T	A	0.0000
79	A	A	0.0000
80	Y	A	-0.6364
81	M	A	0.0000
82	E	A	-1.5339
83	L	A	0.0000
84	K	A	-1.9160
85	S	A	-1.5020
86	L	A	0.0000
87	Q	A	-1.4049
88	F	A	0.1264
89	D	A	-1.2680
90	D	A	0.0000
91	T	A	-0.3797
92	A	A	0.0000
93	V	A	0.4391
94	Y	A	0.0000
95	Y	A	0.2900
96	C	A	0.0000
97	A	A	0.0000
98	R	A	0.0000
99	R	A	-0.3431
100	D	A	-0.3748
101	Y	A	0.0799
102	R	A	-0.7896
103	F	A	0.7506
104	D	A	-0.5064
105	M	A	0.2226
106	G	A	-0.2958
107	F	A	-0.3494
108	D	A	-1.3531
109	Y	A	-0.2088
110	W	A	-0.0032
111	G	A	0.0000
112	Q	A	-1.0243
113	G	A	-0.2156
114	T	A	0.0000
115	T	A	0.4760
116	V	A	0.0000
117	T	A	0.0000
118	V	A	0.0000
119	S	A	-0.4810
120	S	A	-0.6591
121	A	A	-0.6507
122	S	A	-0.7924
123	T	A	-0.8594
124	K	A	-1.7191
125	G	A	-1.7178
126	P	A	-0.7472
127	S	A	-0.2714
128	V	A	0.0000
129	F	A	0.7091
130	P	A	-0.0468
131	L	A	0.4636
132	A	A	-0.6383
133	P	A	0.0000
134	S	A	-1.0018
135	S	A	-1.1807
136	K	A	-1.8977
137	S	A	-1.0507
138	T	A	-1.0451
139	S	A	-0.9390
140	G	A	-0.8613
141	G	A	-0.9061
142	T	A	-0.6390
143	A	A	0.0000
144	A	A	-0.1683
145	L	A	0.0000
146	G	A	0.0000
147	C	A	0.0000
148	L	A	0.6707
149	V	A	0.0000
150	K	A	-0.2960
151	D	A	-0.7876
152	Y	A	0.0000
153	F	A	0.0000
154	P	A	0.0000
155	E	A	-0.7420
156	P	A	-0.9185
157	V	A	-0.6803
158	T	A	-0.5184
159	V	A	-0.3726
160	S	A	-0.3628
161	W	A	0.0000
162	N	A	-0.9315
163	S	A	-0.7171
164	G	A	-0.4937
165	A	A	-0.2641
166	L	A	-0.0645
167	T	A	-0.2924
168	S	A	-0.3581
169	G	A	-0.4329
170	V	A	0.0505
171	H	A	-0.3173
172	T	A	0.2565
173	F	A	0.9464
174	P	A	0.5357
175	A	A	1.2488
176	V	A	2.5393
177	L	A	2.1718
178	Q	A	0.7176
179	S	A	0.1251
180	S	A	-0.1864
181	G	A	0.4388
182	L	A	0.1061
183	Y	A	0.6734
184	S	A	0.0000
185	L	A	0.9100
186	S	A	0.6795
187	S	A	0.0000
188	V	A	0.4518
189	V	A	0.0000
190	T	A	-0.2224
191	V	A	0.0000
192	P	A	-0.5455
193	S	A	-0.6062
194	S	A	-0.6145
195	S	A	0.0000
196	L	A	-0.8579
197	G	A	-1.0445
198	T	A	-0.8702
199	Q	A	-1.5011
200	T	A	-1.2970
201	Y	A	0.0000
202	I	A	-1.4691
203	C	A	0.0000
204	N	A	-1.5014
205	V	A	0.0000
206	N	A	-1.7698
207	H	A	0.0000
208	K	A	-2.7463
209	P	A	-1.8111
210	S	A	-1.9727
211	N	A	-2.5762
212	T	A	-2.1328
213	K	A	-2.6040
214	V	A	-1.6320
215	D	A	-2.6192
216	K	A	-2.0547
217	K	A	-2.6054
218	V	A	0.0000
219	E	A	-2.4885
220	P	A	-1.1471