Project name: 3c09:H
Status: done
submitted: 2019-03-20 15:29:57, status changed: 2019-03-20 17:14:10
Settings
|
Chain sequence(s)
|
H: QVQLVQSGAEVKKPGASVKVSCKASGYTFTSHWMHWVRQAPGQGLEWIGEFNPSNGRTNYNEKFKSKATMTVDTSTNTAYMELSSLRSEDTAVYYCASRDYDYAGRYFDYWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.3212
-
Maximal score value
-
2.3793
-
Average score
-
-0.6141
-
Total score value
-
-132.643
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
H |
-1.3614 |
|
| 2 |
V |
H |
-0.7359 |
|
| 3 |
Q |
H |
-1.1930 |
|
| 4 |
L |
H |
0.0000 |
|
| 5 |
V |
H |
0.1964 |
|
| 6 |
Q |
H |
0.0000 |
|
| 7 |
S |
H |
-0.7029 |
|
| 8 |
G |
H |
-1.0647 |
|
| 9 |
A |
H |
-1.2483 |
|
| 10 |
E |
H |
-1.9330 |
|
| 11 |
V |
H |
-1.2803 |
|
| 12 |
K |
H |
-1.9743 |
|
| 13 |
K |
H |
-2.4713 |
|
| 14 |
P |
H |
-2.1749 |
|
| 15 |
G |
H |
-1.5561 |
|
| 16 |
A |
H |
-1.1738 |
|
| 17 |
S |
H |
-1.3505 |
|
| 18 |
V |
H |
-1.2785 |
|
| 19 |
K |
H |
-1.9660 |
|
| 20 |
V |
H |
0.0000 |
|
| 21 |
S |
H |
-0.6340 |
|
| 22 |
C |
H |
0.0000 |
|
| 23 |
K |
H |
-1.2522 |
|
| 24 |
A |
H |
0.0000 |
|
| 25 |
S |
H |
-0.9156 |
|
| 26 |
G |
H |
-0.9692 |
|
| 27 |
Y |
H |
-0.3793 |
|
| 28 |
T |
H |
-0.1448 |
|
| 29 |
F |
H |
0.0000 |
|
| 30 |
T |
H |
-0.5734 |
|
| 31 |
S |
H |
-0.3541 |
|
| 32 |
H |
H |
-0.2315 |
|
| 33 |
W |
H |
-0.4971 |
|
| 34 |
M |
H |
0.0000 |
|
| 35 |
H |
H |
0.0000 |
|
| 36 |
W |
H |
0.0000 |
|
| 37 |
V |
H |
0.0000 |
|
| 38 |
R |
H |
-0.2844 |
|
| 39 |
Q |
H |
-0.4760 |
|
| 40 |
A |
H |
-0.9952 |
|
| 41 |
P |
H |
-0.8131 |
|
| 42 |
G |
H |
-1.3095 |
|
| 43 |
Q |
H |
-1.6310 |
|
| 44 |
G |
H |
-0.8034 |
|
| 45 |
L |
H |
0.4344 |
|
| 46 |
E |
H |
-0.8605 |
|
| 47 |
W |
H |
-0.4407 |
|
| 48 |
I |
H |
0.0000 |
|
| 49 |
G |
H |
0.0000 |
|
| 50 |
E |
H |
-0.8029 |
|
| 51 |
F |
H |
-0.9304 |
|
| 52 |
N |
H |
-1.3320 |
|
| 53 |
P |
H |
0.0000 |
|
| 54 |
S |
H |
-1.2534 |
|
| 55 |
N |
H |
-2.0956 |
|
| 56 |
G |
H |
-1.8444 |
|
| 57 |
R |
H |
-2.6141 |
|
| 58 |
T |
H |
-1.5615 |
|
| 59 |
N |
H |
-1.7605 |
|
| 60 |
Y |
H |
-1.6431 |
|
| 61 |
N |
H |
-2.3495 |
|
| 62 |
E |
H |
-3.3212 |
|
| 63 |
K |
H |
-3.2826 |
|
| 64 |
F |
H |
0.0000 |
|
| 65 |
K |
H |
-2.9763 |
|
| 66 |
S |
H |
-1.7745 |
|
| 67 |
K |
H |
-1.5590 |
|
| 68 |
A |
H |
0.0000 |
|
| 69 |
T |
H |
-0.8808 |
|
| 70 |
M |
H |
0.0000 |
|
| 71 |
T |
H |
-0.4898 |
|
| 72 |
V |
H |
-0.1718 |
|
| 73 |
D |
H |
-0.8030 |
|
| 74 |
T |
H |
-0.6195 |
|
| 75 |
S |
H |
-0.5520 |
|
| 76 |
T |
H |
-0.7709 |
|
| 77 |
N |
H |
-1.0992 |
|
| 78 |
T |
H |
0.0000 |
|
| 79 |
A |
H |
0.0000 |
|
| 80 |
Y |
H |
-0.6007 |
|
| 81 |
M |
H |
0.0000 |
|
| 82 |
E |
H |
-1.5134 |
|
| 83 |
L |
H |
0.0000 |
|
| 84 |
S |
H |
-1.0616 |
|
| 85 |
S |
H |
-0.9675 |
|
| 86 |
L |
H |
0.0000 |
|
| 87 |
R |
H |
-2.8978 |
|
| 88 |
S |
H |
-2.2761 |
|
| 89 |
E |
H |
-2.4873 |
|
| 90 |
D |
H |
0.0000 |
|
| 91 |
T |
H |
-0.9651 |
|
| 92 |
A |
H |
0.0000 |
|
| 93 |
V |
H |
0.2647 |
|
| 94 |
Y |
H |
0.0000 |
|
| 95 |
Y |
H |
0.2284 |
|
| 96 |
C |
H |
0.0000 |
|
| 97 |
A |
H |
0.0000 |
|
| 98 |
S |
H |
0.0000 |
|
| 99 |
R |
H |
-0.4244 |
|
| 100 |
D |
H |
-0.0286 |
|
| 101 |
Y |
H |
0.7506 |
|
| 102 |
D |
H |
0.1666 |
|
| 103 |
Y |
H |
1.0416 |
|
| 104 |
A |
H |
0.0677 |
|
| 105 |
G |
H |
-0.5112 |
|
| 106 |
R |
H |
-1.2680 |
|
| 107 |
Y |
H |
-0.1598 |
|
| 108 |
F |
H |
-0.2733 |
|
| 109 |
D |
H |
-0.3708 |
|
| 110 |
Y |
H |
0.1092 |
|
| 111 |
W |
H |
0.2688 |
|
| 112 |
G |
H |
-0.2567 |
|
| 113 |
Q |
H |
-0.9111 |
|
| 114 |
G |
H |
-0.2551 |
|
| 115 |
T |
H |
0.0000 |
|
| 116 |
L |
H |
-0.4449 |
|
| 117 |
V |
H |
0.0000 |
|
| 118 |
T |
H |
-1.2170 |
|
| 119 |
V |
H |
0.0000 |
|
| 120 |
S |
H |
-1.3410 |
|
| 121 |
S |
H |
-0.9573 |
|
| 122 |
A |
H |
-0.6753 |
|
| 123 |
S |
H |
-0.7299 |
|
| 124 |
T |
H |
-0.8756 |
|
| 125 |
K |
H |
-1.2181 |
|
| 126 |
G |
H |
-1.4056 |
|
| 127 |
P |
H |
-0.5837 |
|
| 128 |
S |
H |
-0.0500 |
|
| 129 |
V |
H |
0.5305 |
|
| 130 |
F |
H |
1.7294 |
|
| 131 |
P |
H |
0.5628 |
|
| 132 |
L |
H |
0.4810 |
|
| 133 |
A |
H |
-0.8012 |
|
| 134 |
P |
H |
-0.7479 |
|
| 135 |
S |
H |
-0.4164 |
|
| 142 |
G |
H |
-0.6120 |
|
| 143 |
T |
H |
-0.4807 |
|
| 144 |
A |
H |
0.0000 |
|
| 145 |
A |
H |
0.0780 |
|
| 146 |
L |
H |
0.0000 |
|
| 147 |
G |
H |
0.0000 |
|
| 148 |
C |
H |
0.0000 |
|
| 149 |
L |
H |
0.9444 |
|
| 150 |
V |
H |
0.0000 |
|
| 151 |
K |
H |
-0.3744 |
|
| 152 |
D |
H |
-0.5100 |
|
| 153 |
Y |
H |
0.0000 |
|
| 154 |
F |
H |
0.0000 |
|
| 155 |
P |
H |
0.0000 |
|
| 156 |
E |
H |
-0.7266 |
|
| 157 |
P |
H |
-0.9528 |
|
| 158 |
V |
H |
-0.5542 |
|
| 159 |
T |
H |
-0.4926 |
|
| 160 |
V |
H |
0.0056 |
|
| 161 |
S |
H |
-0.3498 |
|
| 162 |
W |
H |
0.0000 |
|
| 163 |
N |
H |
-0.8806 |
|
| 164 |
S |
H |
-0.6951 |
|
| 165 |
G |
H |
-0.5882 |
|
| 166 |
A |
H |
-0.2823 |
|
| 167 |
L |
H |
-0.0355 |
|
| 168 |
T |
H |
-0.3173 |
|
| 169 |
S |
H |
-0.3686 |
|
| 170 |
G |
H |
-0.4558 |
|
| 171 |
V |
H |
0.0886 |
|
| 172 |
H |
H |
-0.3329 |
|
| 173 |
T |
H |
0.2905 |
|
| 174 |
F |
H |
1.0945 |
|
| 175 |
P |
H |
0.7809 |
|
| 176 |
A |
H |
1.2048 |
|
| 177 |
V |
H |
2.3793 |
|
| 178 |
L |
H |
2.1449 |
|
| 179 |
Q |
H |
0.7287 |
|
| 180 |
S |
H |
0.1028 |
|
| 181 |
S |
H |
-0.2138 |
|
| 182 |
G |
H |
0.1816 |
|
| 183 |
L |
H |
0.3130 |
|
| 184 |
Y |
H |
0.9388 |
|
| 185 |
S |
H |
0.0000 |
|
| 186 |
L |
H |
0.0000 |
|
| 187 |
S |
H |
0.7532 |
|
| 188 |
S |
H |
0.0000 |
|
| 189 |
V |
H |
0.5463 |
|
| 190 |
V |
H |
0.0000 |
|
| 191 |
T |
H |
-0.2039 |
|
| 192 |
V |
H |
0.0000 |
|
| 193 |
P |
H |
-0.4704 |
|
| 194 |
S |
H |
-0.5962 |
|
| 195 |
S |
H |
-0.6104 |
|
| 196 |
S |
H |
-0.6069 |
|
| 197 |
L |
H |
-0.7553 |
|
| 198 |
G |
H |
-0.9327 |
|
| 199 |
T |
H |
-0.7111 |
|
| 200 |
Q |
H |
-1.1697 |
|
| 201 |
T |
H |
-1.0791 |
|
| 202 |
Y |
H |
0.0000 |
|
| 203 |
I |
H |
-1.3049 |
|
| 204 |
C |
H |
0.0000 |
|
| 205 |
N |
H |
-1.4178 |
|
| 206 |
V |
H |
0.0000 |
|
| 207 |
N |
H |
-1.6779 |
|
| 208 |
H |
H |
0.0000 |
|
| 209 |
K |
H |
-2.7745 |
|
| 210 |
P |
H |
-1.9440 |
|
| 211 |
S |
H |
-1.9266 |
|
| 212 |
N |
H |
-2.4372 |
|
| 213 |
T |
H |
-1.9401 |
|
| 214 |
K |
H |
-2.5850 |
|
| 215 |
V |
H |
-1.7572 |
|
| 216 |
D |
H |
-2.6196 |
|
| 217 |
K |
H |
-1.9251 |
|
| 218 |
K |
H |
-2.3267 |
|
| 219 |
V |
H |
0.0000 |
|
| 220 |
E |
H |
-2.7148 |
|
| 221 |
P |
H |
-1.8769 |
|
| 222 |
K |
H |
-2.2535 |
|