Project name: 5iv2:A
Status: done
submitted: 2019-03-20 20:32:44, status changed: 2019-03-20 20:44:01
Settings
|
Chain sequence(s)
|
A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEEDIADYYCQQNNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGA
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.7867
-
Maximal score value
-
2.1649
-
Average score
-
-0.802
-
Total score value
-
-170.8297
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-1.4502 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
L |
A |
0.7227 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
T |
A |
-0.2403 |
|
| 6 |
Q |
A |
0.0000 |
|
| 7 |
S |
A |
0.1986 |
|
| 8 |
P |
A |
1.0110 |
|
| 9 |
V |
A |
2.1649 |
|
| 10 |
I |
A |
1.8049 |
|
| 11 |
L |
A |
0.8477 |
|
| 12 |
S |
A |
-0.2191 |
|
| 13 |
V |
A |
-1.1438 |
|
| 14 |
S |
A |
-1.7653 |
|
| 15 |
P |
A |
-1.9473 |
|
| 16 |
G |
A |
-2.1858 |
|
| 17 |
E |
A |
-2.9498 |
|
| 18 |
R |
A |
-3.2968 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
S |
A |
-0.7830 |
|
| 21 |
F |
A |
0.0000 |
|
| 22 |
S |
A |
-1.0301 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.5529 |
|
| 25 |
A |
A |
0.0000 |
|
| 26 |
S |
A |
-1.1263 |
|
| 27 |
Q |
A |
-1.8455 |
|
| 28 |
S |
A |
-1.6541 |
|
| 29 |
I |
A |
0.0000 |
|
| 30 |
G |
A |
-1.0725 |
|
| 31 |
T |
A |
-0.7203 |
|
| 32 |
N |
A |
-0.9708 |
|
| 33 |
I |
A |
0.0000 |
|
| 34 |
H |
A |
0.0000 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.0879 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-1.5618 |
|
| 39 |
R |
A |
-2.2436 |
|
| 40 |
T |
A |
-1.8830 |
|
| 41 |
N |
A |
-1.9549 |
|
| 42 |
G |
A |
-1.5863 |
|
| 43 |
S |
A |
-1.1244 |
|
| 44 |
P |
A |
-1.0874 |
|
| 45 |
R |
A |
-0.9116 |
|
| 46 |
L |
A |
-0.1705 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
K |
A |
-0.8177 |
|
| 50 |
Y |
A |
-0.2341 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
-1.1379 |
|
| 53 |
E |
A |
-1.9185 |
|
| 54 |
S |
A |
-1.1182 |
|
| 55 |
I |
A |
-0.5273 |
|
| 56 |
S |
A |
-0.2546 |
|
| 57 |
G |
A |
-0.4024 |
|
| 58 |
I |
A |
-0.1615 |
|
| 59 |
P |
A |
-0.2976 |
|
| 60 |
S |
A |
-0.5614 |
|
| 61 |
R |
A |
-1.1153 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
-0.9740 |
|
| 64 |
G |
A |
-0.7148 |
|
| 65 |
S |
A |
-0.7662 |
|
| 66 |
G |
A |
-1.0227 |
|
| 67 |
S |
A |
-1.0576 |
|
| 68 |
G |
A |
-1.4063 |
|
| 69 |
T |
A |
-1.9939 |
|
| 70 |
D |
A |
-2.5966 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.9040 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
S |
A |
-0.9475 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
N |
A |
-2.5592 |
|
| 77 |
S |
A |
-2.3759 |
|
| 78 |
V |
A |
0.0000 |
|
| 79 |
E |
A |
-2.4850 |
|
| 80 |
S |
A |
-2.2043 |
|
| 81 |
E |
A |
-1.8089 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
I |
A |
0.0000 |
|
| 84 |
A |
A |
0.0000 |
|
| 85 |
D |
A |
-0.7227 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
0.2132 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.2735 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
N |
A |
-1.4877 |
|
| 92 |
N |
A |
-1.6205 |
|
| 93 |
N |
A |
-1.4476 |
|
| 94 |
W |
A |
-0.0338 |
|
| 95 |
P |
A |
-0.2166 |
|
| 96 |
T |
A |
-0.5611 |
|
| 97 |
T |
A |
0.2606 |
|
| 98 |
F |
A |
1.4248 |
|
| 99 |
G |
A |
0.6550 |
|
| 100 |
A |
A |
0.6489 |
|
| 101 |
G |
A |
0.4719 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
0.2985 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
E |
A |
-0.8807 |
|
| 106 |
L |
A |
0.0000 |
|
| 107 |
K |
A |
-1.6175 |
|
| 108 |
R |
A |
-1.1901 |
|
| 109 |
T |
A |
-0.1215 |
|
| 110 |
V |
A |
0.2921 |
|
| 111 |
A |
A |
0.0512 |
|
| 112 |
A |
A |
-0.2083 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
-0.1191 |
|
| 115 |
V |
A |
0.0000 |
|
| 116 |
F |
A |
1.4576 |
|
| 117 |
I |
A |
1.3581 |
|
| 118 |
F |
A |
1.5240 |
|
| 119 |
P |
A |
0.0174 |
|
| 120 |
P |
A |
-0.7147 |
|
| 121 |
S |
A |
-1.8130 |
|
| 122 |
D |
A |
-3.2538 |
|
| 123 |
E |
A |
-3.4585 |
|
| 124 |
Q |
A |
-2.5183 |
|
| 125 |
L |
A |
-2.6124 |
|
| 126 |
K |
A |
-3.0389 |
|
| 127 |
S |
A |
-1.9054 |
|
| 128 |
G |
A |
-1.3205 |
|
| 129 |
T |
A |
-1.1541 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
0.0401 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.7419 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.5501 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.5315 |
|
| 138 |
N |
A |
-1.4117 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
-1.2702 |
|
| 141 |
P |
A |
-1.7679 |
|
| 142 |
R |
A |
-3.0695 |
|
| 143 |
E |
A |
-3.2501 |
|
| 144 |
A |
A |
-2.3473 |
|
| 145 |
K |
A |
-2.3663 |
|
| 146 |
V |
A |
-1.2299 |
|
| 147 |
Q |
A |
-0.8769 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.6805 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-1.8275 |
|
| 152 |
N |
A |
-1.3492 |
|
| 153 |
A |
A |
-0.3070 |
|
| 154 |
L |
A |
0.5747 |
|
| 155 |
Q |
A |
-0.3112 |
|
| 156 |
S |
A |
-0.4546 |
|
| 157 |
G |
A |
-1.0378 |
|
| 158 |
N |
A |
-1.0303 |
|
| 159 |
S |
A |
-1.4472 |
|
| 160 |
Q |
A |
-2.3014 |
|
| 161 |
E |
A |
-2.3251 |
|
| 162 |
S |
A |
-1.2848 |
|
| 163 |
V |
A |
-0.7355 |
|
| 164 |
T |
A |
-1.0589 |
|
| 165 |
E |
A |
-2.1071 |
|
| 166 |
Q |
A |
0.0000 |
|
| 167 |
D |
A |
-2.2608 |
|
| 168 |
S |
A |
-2.2929 |
|
| 169 |
K |
A |
-2.7936 |
|
| 170 |
D |
A |
-2.3251 |
|
| 171 |
S |
A |
0.0000 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
0.0000 |
|
| 174 |
S |
A |
-0.9546 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.4454 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.5975 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.5376 |
|
| 181 |
L |
A |
-0.7950 |
|
| 182 |
S |
A |
-1.1465 |
|
| 183 |
K |
A |
-2.1371 |
|
| 184 |
A |
A |
-2.0361 |
|
| 185 |
D |
A |
-2.8106 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.7425 |
|
| 188 |
K |
A |
-3.7867 |
|
| 189 |
H |
A |
-3.0713 |
|
| 190 |
K |
A |
-2.8500 |
|
| 191 |
V |
A |
-1.2557 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
0.0000 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-0.9112 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.2717 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.5696 |
|
| 200 |
G |
A |
-0.4003 |
|
| 201 |
L |
A |
-0.1955 |
|
| 202 |
S |
A |
-0.4377 |
|
| 203 |
S |
A |
-0.4270 |
|
| 204 |
P |
A |
-0.6305 |
|
| 205 |
V |
A |
-0.0497 |
|
| 206 |
T |
A |
-0.2895 |
|
| 207 |
K |
A |
-0.1512 |
|
| 208 |
S |
A |
-0.2041 |
|
| 209 |
F |
A |
-0.3999 |
|
| 210 |
N |
A |
-1.3873 |
|
| 211 |
R |
A |
-2.1591 |
|
| 212 |
G |
A |
-1.1189 |
|
| 213 |
A |
A |
-0.6660 |
|