Project name: 2m3o DI1000193

Chain sequence(s)	P: TAPPPAYATLG; W: GSMEQGFLPKGWEVRHAPNGRPFFIDHNTKTTTWEDPRLKIPA
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.6733
• Maximal score value: 1.1599
• Average score: -0.7833
• Total score value: -42.2956

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
416	G	W	-0.4580
417	S	W	-0.6617
418	M	W	-0.5934
419	E	W	-1.7743
420	Q	W	-1.0608
421	G	W	-0.2419
422	F	W	1.0806
423	L	W	0.1462
424	P	W	-0.6108
425	K	W	-1.8024
426	G	W	-1.6875
427	W	W	-0.8798
428	E	W	-0.8399
429	V	W	-0.5862
430	R	W	-1.9455
431	H	W	-2.3670
432	A	W	0.0000
433	P	W	-1.7008
434	N	W	-2.2666
435	G	W	-2.3447
436	R	W	-2.6733
437	P	W	-2.0771
438	F	W	0.0000
439	F	W	0.0000
440	I	W	0.0000
441	D	W	0.0000
442	H	W	-1.8524
443	N	W	-2.1744
444	T	W	-1.5838
445	K	W	-2.0898
446	T	W	-1.0891
447	T	W	-0.7693
448	T	W	-0.5164
449	W	W	-0.9171
450	E	W	-1.9422
451	D	W	-1.4940
452	P	W	-0.6995
453	R	W	-0.7499
454	L	W	-0.2044
455	K	W	-0.7155
456	I	W	1.1599
457	P	W	0.3688
458	A	W	0.2750
638	T	P	-0.1023
639	A	P	-0.2889
640	P	P	-0.2403
641	P	P	-0.6778
642	P	P	-0.2573
643	A	P	-0.1547
644	Y	P	-0.1818
645	A	P	-0.0728
646	T	P	0.1167
647	L	P	0.0867
648	G	P	-0.1841