Project name: 5csz:L
Status: done
submitted: 2019-03-20 20:25:07, status changed: 2019-03-20 20:37:49
Settings
|
Chain sequence(s)
|
L: DIVLTQSPATLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGVPARFSGSGSGTDFTLTISSLEPEDFATYYCLQIYNMPITFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.5179
-
Maximal score value
-
1.9274
-
Average score
-
-0.7636
-
Total score value
-
-162.6397
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.3257 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
V |
L |
1.1011 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
T |
L |
-0.2742 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.6032 |
|
| 8 |
P |
L |
-0.3151 |
|
| 9 |
A |
L |
-0.5847 |
|
| 10 |
T |
L |
-0.6761 |
|
| 11 |
L |
L |
-0.4820 |
|
| 12 |
S |
L |
-0.7254 |
|
| 13 |
L |
L |
-1.0497 |
|
| 14 |
S |
L |
-1.4668 |
|
| 15 |
P |
L |
-1.8182 |
|
| 16 |
G |
L |
-1.8803 |
|
| 17 |
E |
L |
-2.4863 |
|
| 18 |
R |
L |
-2.6648 |
|
| 19 |
A |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6515 |
|
| 21 |
L |
L |
0.0000 |
|
| 22 |
S |
L |
-0.7678 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-1.7991 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-0.8721 |
|
| 27 |
Q |
L |
-1.4900 |
|
| 28 |
S |
L |
-1.1818 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
S |
L |
-0.0247 |
|
| 31 |
S |
L |
-0.2845 |
|
| 32 |
S |
L |
0.2831 |
|
| 33 |
Y |
L |
0.9264 |
|
| 34 |
L |
L |
0.0000 |
|
| 35 |
A |
L |
0.0000 |
|
| 36 |
W |
L |
0.0000 |
|
| 37 |
Y |
L |
0.3261 |
|
| 38 |
Q |
L |
0.0000 |
|
| 39 |
Q |
L |
-1.3099 |
|
| 40 |
K |
L |
-1.8435 |
|
| 41 |
P |
L |
-1.4819 |
|
| 42 |
G |
L |
-1.3734 |
|
| 43 |
Q |
L |
-1.9165 |
|
| 44 |
A |
L |
-1.0798 |
|
| 45 |
P |
L |
-0.9761 |
|
| 46 |
R |
L |
-0.9703 |
|
| 47 |
L |
L |
0.0816 |
|
| 48 |
L |
L |
0.0000 |
|
| 49 |
I |
L |
0.0000 |
|
| 50 |
Y |
L |
0.4839 |
|
| 51 |
G |
L |
-0.0237 |
|
| 52 |
A |
L |
0.0000 |
|
| 53 |
S |
L |
-0.6677 |
|
| 54 |
S |
L |
-0.7619 |
|
| 55 |
R |
L |
-1.2619 |
|
| 56 |
A |
L |
-0.6155 |
|
| 57 |
T |
L |
-0.5521 |
|
| 58 |
G |
L |
-0.6403 |
|
| 59 |
V |
L |
0.0000 |
|
| 60 |
P |
L |
-0.4843 |
|
| 61 |
A |
L |
-0.4436 |
|
| 62 |
R |
L |
-0.8872 |
|
| 63 |
F |
L |
0.0000 |
|
| 64 |
S |
L |
-0.6297 |
|
| 65 |
G |
L |
-0.5123 |
|
| 66 |
S |
L |
-0.8233 |
|
| 67 |
G |
L |
-1.2612 |
|
| 68 |
S |
L |
-1.2669 |
|
| 69 |
G |
L |
-1.3174 |
|
| 70 |
T |
L |
-1.8517 |
|
| 71 |
D |
L |
-2.6284 |
|
| 72 |
F |
L |
0.0000 |
|
| 73 |
T |
L |
-0.8343 |
|
| 74 |
L |
L |
0.0000 |
|
| 75 |
T |
L |
-0.6368 |
|
| 76 |
I |
L |
0.0000 |
|
| 77 |
S |
L |
-1.5341 |
|
| 78 |
S |
L |
-1.8465 |
|
| 79 |
L |
L |
0.0000 |
|
| 80 |
E |
L |
-2.0266 |
|
| 81 |
P |
L |
-1.8897 |
|
| 82 |
E |
L |
-2.3053 |
|
| 83 |
D |
L |
0.0000 |
|
| 84 |
F |
L |
-1.1431 |
|
| 85 |
A |
L |
0.0000 |
|
| 86 |
T |
L |
0.0000 |
|
| 87 |
Y |
L |
0.0000 |
|
| 88 |
Y |
L |
0.0570 |
|
| 89 |
C |
L |
0.0000 |
|
| 90 |
L |
L |
0.0000 |
|
| 91 |
Q |
L |
0.0000 |
|
| 92 |
I |
L |
1.7604 |
|
| 93 |
Y |
L |
0.9371 |
|
| 94 |
N |
L |
-0.1603 |
|
| 95 |
M |
L |
0.7237 |
|
| 96 |
P |
L |
0.8426 |
|
| 97 |
I |
L |
1.7947 |
|
| 98 |
T |
L |
1.4649 |
|
| 99 |
F |
L |
1.9274 |
|
| 100 |
G |
L |
0.0000 |
|
| 101 |
Q |
L |
-0.7563 |
|
| 102 |
G |
L |
-0.7071 |
|
| 103 |
T |
L |
0.0000 |
|
| 104 |
K |
L |
-1.8364 |
|
| 105 |
V |
L |
0.0000 |
|
| 106 |
E |
L |
-1.3310 |
|
| 107 |
I |
L |
-0.9666 |
|
| 108 |
K |
L |
-1.2756 |
|
| 109 |
R |
L |
-0.9167 |
|
| 110 |
T |
L |
-0.0976 |
|
| 111 |
V |
L |
0.2099 |
|
| 112 |
A |
L |
-0.1849 |
|
| 113 |
A |
L |
-0.2654 |
|
| 114 |
P |
L |
0.0000 |
|
| 115 |
S |
L |
-0.0917 |
|
| 116 |
V |
L |
0.0000 |
|
| 117 |
F |
L |
1.3561 |
|
| 118 |
I |
L |
1.3304 |
|
| 119 |
F |
L |
1.5234 |
|
| 120 |
P |
L |
-0.0417 |
|
| 121 |
P |
L |
0.0000 |
|
| 122 |
S |
L |
-1.7459 |
|
| 123 |
D |
L |
-3.2093 |
|
| 124 |
E |
L |
-3.4179 |
|
| 125 |
Q |
L |
-2.4469 |
|
| 126 |
L |
L |
-2.5493 |
|
| 127 |
K |
L |
-3.0156 |
|
| 128 |
S |
L |
-1.8663 |
|
| 129 |
G |
L |
-1.4085 |
|
| 130 |
T |
L |
-1.0869 |
|
| 131 |
A |
L |
0.0000 |
|
| 132 |
S |
L |
0.0549 |
|
| 133 |
V |
L |
0.0000 |
|
| 134 |
V |
L |
0.7526 |
|
| 135 |
C |
L |
0.0000 |
|
| 136 |
L |
L |
0.5843 |
|
| 137 |
L |
L |
0.0000 |
|
| 138 |
N |
L |
-0.4676 |
|
| 139 |
N |
L |
-1.2562 |
|
| 140 |
F |
L |
0.0000 |
|
| 141 |
Y |
L |
0.0000 |
|
| 142 |
P |
L |
-1.7056 |
|
| 143 |
R |
L |
-2.9835 |
|
| 144 |
E |
L |
-3.1838 |
|
| 145 |
A |
L |
-2.3378 |
|
| 146 |
K |
L |
-2.4733 |
|
| 147 |
V |
L |
-1.1615 |
|
| 148 |
Q |
L |
-0.6882 |
|
| 149 |
W |
L |
0.0000 |
|
| 150 |
K |
L |
-0.7991 |
|
| 151 |
V |
L |
0.0000 |
|
| 152 |
D |
L |
-2.1022 |
|
| 153 |
N |
L |
-1.6389 |
|
| 154 |
A |
L |
-0.3467 |
|
| 155 |
L |
L |
0.6213 |
|
| 156 |
Q |
L |
-0.1577 |
|
| 157 |
S |
L |
-0.4068 |
|
| 158 |
G |
L |
-0.9253 |
|
| 159 |
N |
L |
-1.1177 |
|
| 160 |
S |
L |
-1.4856 |
|
| 161 |
Q |
L |
-2.3285 |
|
| 162 |
E |
L |
-2.3710 |
|
| 163 |
S |
L |
-1.2090 |
|
| 164 |
V |
L |
-0.9000 |
|
| 165 |
T |
L |
-1.3250 |
|
| 166 |
E |
L |
-2.3957 |
|
| 167 |
Q |
L |
-2.1741 |
|
| 168 |
D |
L |
-2.3390 |
|
| 169 |
S |
L |
-2.1483 |
|
| 170 |
K |
L |
-2.4187 |
|
| 171 |
D |
L |
-1.9097 |
|
| 172 |
S |
L |
-1.9559 |
|
| 173 |
T |
L |
0.0000 |
|
| 174 |
Y |
L |
0.0000 |
|
| 175 |
S |
L |
-1.0223 |
|
| 176 |
L |
L |
0.0000 |
|
| 177 |
S |
L |
-0.4959 |
|
| 178 |
S |
L |
0.0000 |
|
| 179 |
T |
L |
-0.6202 |
|
| 180 |
L |
L |
0.0000 |
|
| 181 |
T |
L |
-0.4444 |
|
| 182 |
L |
L |
-0.6656 |
|
| 183 |
S |
L |
-1.1846 |
|
| 184 |
K |
L |
-2.0300 |
|
| 185 |
A |
L |
-1.7997 |
|
| 186 |
D |
L |
-2.4740 |
|
| 187 |
Y |
L |
0.0000 |
|
| 188 |
E |
L |
-3.3166 |
|
| 189 |
K |
L |
-3.5179 |
|
| 190 |
H |
L |
-3.0560 |
|
| 191 |
K |
L |
-3.1929 |
|
| 192 |
V |
L |
-1.5845 |
|
| 193 |
Y |
L |
0.0000 |
|
| 194 |
A |
L |
-0.7789 |
|
| 195 |
C |
L |
0.0000 |
|
| 196 |
E |
L |
-1.0811 |
|
| 197 |
V |
L |
0.0000 |
|
| 198 |
T |
L |
-1.2767 |
|
| 199 |
H |
L |
0.0000 |
|
| 200 |
Q |
L |
-1.8026 |
|
| 201 |
G |
L |
-0.4896 |
|
| 202 |
L |
L |
-0.2713 |
|
| 203 |
S |
L |
-0.4773 |
|
| 204 |
S |
L |
-0.4194 |
|
| 205 |
P |
L |
-0.5637 |
|
| 206 |
V |
L |
-0.0281 |
|
| 207 |
T |
L |
-0.4141 |
|
| 208 |
K |
L |
-0.2375 |
|
| 209 |
S |
L |
-0.4170 |
|
| 210 |
F |
L |
-0.7463 |
|
| 211 |
N |
L |
-2.1278 |
|
| 212 |
R |
L |
-2.4040 |
|
| 213 |
G |
L |
-1.5314 |
|