Project name: 1yy9:D

Chain sequence(s)	D: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9713
• Maximal score value: 2.4576
• Average score: -0.4814
• Total score value: -105.9064

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	D	-1.5036
2	V	D	-0.8250
3	Q	D	-1.7217
4	L	D	0.0000
5	K	D	-1.7637
6	Q	D	0.0000
7	S	D	-0.7281
8	G	D	-0.2412
9	P	D	-0.2218
10	G	D	0.0710
11	L	D	0.1147
12	V	D	0.0000
13	Q	D	-1.5907
14	P	D	-1.5217
15	S	D	-1.6319
16	Q	D	-2.0810
17	S	D	-1.7971
18	L	D	0.0000
19	S	D	-0.8006
20	I	D	0.0000
21	T	D	-0.5713
22	C	D	0.0000
23	T	D	-1.1267
24	V	D	0.0000
25	S	D	-1.3280
26	G	D	-1.0775
27	F	D	-0.5472
28	S	D	-0.8238
29	L	D	0.0000
30	T	D	-0.8841
31	N	D	-0.6027
32	Y	D	0.2948
33	G	D	0.0912
34	V	D	0.0000
35	H	D	0.0000
36	W	D	0.0000
37	V	D	0.0000
38	R	D	0.0000
39	Q	D	-0.0312
40	S	D	0.0000
41	P	D	-0.6891
42	G	D	-1.2772
43	K	D	-1.6037
44	G	D	-0.5146
45	L	D	0.8592
46	E	D	0.1104
47	W	D	0.3365
48	L	D	0.0000
49	G	D	0.0000
50	V	D	0.0000
51	I	D	0.0000
52	W	D	-0.6876
53	S	D	-0.6366
54	G	D	-1.1851
55	G	D	-1.5243
56	N	D	-2.0996
57	T	D	-1.7715
58	D	D	-2.0133
59	Y	D	-0.8991
60	N	D	-0.7538
61	T	D	-0.5689
62	P	D	-0.4590
63	F	D	0.0000
64	T	D	-0.6705
65	S	D	-0.6191
66	R	D	-1.0262
67	L	D	0.0000
68	S	D	-1.0860
69	I	D	0.0000
70	N	D	-1.7510
71	K	D	-1.6747
72	D	D	-1.8309
73	N	D	-2.1783
74	S	D	-1.6867
75	K	D	-2.3902
76	S	D	-1.7002
77	Q	D	-1.6178
78	V	D	0.0000
79	F	D	-0.5105
80	F	D	0.0000
81	K	D	-1.3975
82	M	D	0.0000
83	N	D	-2.0071
84	S	D	-1.6361
85	L	D	0.0000
86	Q	D	-2.0188
87	S	D	-1.4467
88	N	D	-1.8809
89	D	D	0.0000
90	T	D	-0.4405
91	A	D	0.0000
92	I	D	0.7979
93	Y	D	0.0000
94	Y	D	0.2036
95	C	D	0.0000
96	A	D	0.0000
97	R	D	0.0000
98	A	D	0.0000
99	L	D	1.8567
100	T	D	1.4484
101	Y	D	1.8889
102	Y	D	1.7400
103	D	D	0.6986
104	Y	D	1.1114
105	E	D	0.3686
106	F	D	0.7625
107	A	D	0.9039
108	Y	D	0.3566
109	W	D	0.0039
110	G	D	0.0000
111	Q	D	-1.3229
112	G	D	-0.3862
113	T	D	0.1238
114	L	D	0.7497
115	V	D	0.0000
116	T	D	0.0001
117	V	D	0.0000
118	S	D	-0.5539
119	A	D	-0.5820
120	A	D	-0.2927
121	S	D	-0.4548
122	T	D	-0.5576
123	K	D	-1.1443
124	G	D	-1.3584
125	P	D	0.0000
126	S	D	-0.1072
127	V	D	0.0000
128	F	D	0.8903
129	P	D	0.0657
130	L	D	0.5957
131	A	D	-0.7376
132	P	D	-0.9555
133	S	D	-0.9675
134	S	D	-1.4722
135	K	D	-2.0465
136	S	D	-1.2397
137	T	D	-0.8899
138	S	D	-0.8353
139	G	D	-0.4308
140	G	D	-0.5519
141	T	D	-0.4669
142	A	D	-0.5660
143	A	D	0.0755
144	L	D	0.0000
145	G	D	0.0000
146	C	D	0.0000
147	L	D	0.7427
148	V	D	0.0000
149	K	D	-0.1414
150	D	D	-0.5442
151	Y	D	0.0000
152	F	D	0.0000
153	P	D	0.0000
154	E	D	-0.3842
155	P	D	-0.6150
156	V	D	-0.6092
157	T	D	-0.5456
158	V	D	-0.2562
159	S	D	-0.4373
160	W	D	0.0000
161	N	D	-0.7358
162	S	D	-0.6816
163	G	D	-0.5441
164	A	D	-0.2284
165	L	D	0.0318
166	T	D	-0.2116
167	S	D	-0.3129
168	G	D	-0.3522
169	V	D	0.0745
170	H	D	-0.4484
171	T	D	0.1482
172	F	D	0.9734
173	P	D	0.6798
174	A	D	1.2613
175	V	D	2.4576
176	L	D	2.0089
177	Q	D	0.6403
178	S	D	0.0433
179	S	D	-0.2518
180	G	D	0.1432
181	L	D	0.2573
182	Y	D	0.8326
183	S	D	0.0000
184	L	D	0.0000
185	S	D	0.6807
186	S	D	0.0000
187	V	D	0.4349
188	V	D	0.0000
189	T	D	-0.2394
190	V	D	0.0000
191	P	D	-0.0923
192	S	D	0.0000
193	S	D	-0.5116
194	S	D	-0.2701
195	L	D	0.7555
196	G	D	-0.1106
197	T	D	-0.4623
198	Q	D	-1.3026
199	T	D	-1.2314
200	Y	D	0.0000
201	I	D	-1.5513
202	C	D	0.0000
203	N	D	-1.6003
204	V	D	0.0000
205	N	D	-1.8961
206	H	D	0.0000
207	K	D	-2.7180
208	P	D	-1.5612
209	S	D	-1.8387
210	N	D	-2.6095
211	T	D	-2.0394
212	K	D	-2.6941
213	V	D	-1.8110
214	D	D	-2.6479
215	K	D	-1.9551
216	R	D	-2.8590
217	V	D	0.0000
218	E	D	-2.9713
219	P	D	-2.1400
220	K	D	-2.5854