Project name: 5wux:L
Status: done
submitted: 2019-03-20 20:39:49, status changed: 2019-03-20 20:49:19
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSSLSASVGDRVTITCKASQNVGTNVAWYQQKPGKAPKALIYSASFLYSGVPYRFSGSGSGTDFTLTISSLQPEDFATYYCQQYNIYPLTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.4104
-
Maximal score value
-
2.3937
-
Average score
-
-0.7091
-
Total score value
-
-151.0337
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.5087 |
|
| 2 |
I |
L |
-0.9397 |
|
| 3 |
Q |
L |
-1.8502 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-1.0720 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.6770 |
|
| 8 |
P |
L |
-0.6020 |
|
| 9 |
S |
L |
-1.0296 |
|
| 10 |
S |
L |
-1.0588 |
|
| 11 |
L |
L |
-0.6851 |
|
| 12 |
S |
L |
-0.8044 |
|
| 13 |
A |
L |
-0.8784 |
|
| 14 |
S |
L |
-0.7058 |
|
| 15 |
V |
L |
0.0585 |
|
| 16 |
G |
L |
-0.7751 |
|
| 17 |
D |
L |
-1.8401 |
|
| 18 |
R |
L |
-2.4100 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6549 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.7017 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
K |
L |
-2.3687 |
|
| 25 |
A |
L |
-1.9308 |
|
| 26 |
S |
L |
-2.0722 |
|
| 27 |
Q |
L |
-2.5946 |
|
| 28 |
N |
L |
-2.4682 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
G |
L |
-1.2629 |
|
| 31 |
T |
L |
-0.8747 |
|
| 32 |
N |
L |
-0.5576 |
|
| 33 |
V |
L |
0.0000 |
|
| 34 |
A |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.0933 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.5123 |
|
| 39 |
K |
L |
-1.8790 |
|
| 40 |
P |
L |
-1.6566 |
|
| 41 |
G |
L |
-1.6748 |
|
| 42 |
K |
L |
-2.3468 |
|
| 43 |
A |
L |
-1.4370 |
|
| 44 |
P |
L |
-1.4464 |
|
| 45 |
K |
L |
-1.6413 |
|
| 46 |
A |
L |
-0.4374 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
1.2435 |
|
| 50 |
S |
L |
0.4657 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
0.7559 |
|
| 53 |
F |
L |
2.2175 |
|
| 54 |
L |
L |
1.8058 |
|
| 55 |
Y |
L |
1.1501 |
|
| 56 |
S |
L |
0.3109 |
|
| 57 |
G |
L |
-0.1912 |
|
| 58 |
V |
L |
0.0000 |
|
| 59 |
P |
L |
0.4078 |
|
| 60 |
Y |
L |
1.0978 |
|
| 61 |
R |
L |
-0.1373 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
0.2886 |
|
| 64 |
G |
L |
0.2037 |
|
| 65 |
S |
L |
-0.3016 |
|
| 66 |
G |
L |
-0.9809 |
|
| 67 |
S |
L |
-1.2257 |
|
| 68 |
G |
L |
-1.5373 |
|
| 69 |
T |
L |
-1.9658 |
|
| 70 |
D |
L |
-2.0879 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.6405 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.6236 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.2431 |
|
| 77 |
S |
L |
-1.0721 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-0.9964 |
|
| 80 |
P |
L |
-1.4534 |
|
| 81 |
E |
L |
-1.7402 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
0.0000 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
0.0000 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.0184 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
Y |
L |
1.4845 |
|
| 92 |
N |
L |
0.5207 |
|
| 93 |
I |
L |
2.3937 |
|
| 94 |
Y |
L |
2.2685 |
|
| 95 |
P |
L |
1.4393 |
|
| 96 |
L |
L |
1.8949 |
|
| 97 |
T |
L |
0.8993 |
|
| 98 |
F |
L |
1.1987 |
|
| 99 |
G |
L |
-0.3264 |
|
| 100 |
Q |
L |
-1.2676 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-2.1005 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-1.3092 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.0373 |
|
| 108 |
R |
L |
-0.7912 |
|
| 109 |
T |
L |
-0.1362 |
|
| 110 |
V |
L |
0.2000 |
|
| 111 |
A |
L |
-0.0996 |
|
| 112 |
A |
L |
-0.3103 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.3068 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.1004 |
|
| 117 |
I |
L |
1.1750 |
|
| 118 |
F |
L |
1.5042 |
|
| 119 |
P |
L |
-0.1348 |
|
| 120 |
P |
L |
-0.6101 |
|
| 121 |
S |
L |
-1.8361 |
|
| 122 |
D |
L |
-3.2912 |
|
| 123 |
E |
L |
-3.4104 |
|
| 124 |
Q |
L |
-2.4414 |
|
| 125 |
L |
L |
-2.5722 |
|
| 126 |
K |
L |
-3.0414 |
|
| 127 |
S |
L |
-1.9053 |
|
| 128 |
G |
L |
-1.7468 |
|
| 129 |
T |
L |
-1.4341 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
-0.0792 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7342 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.4102 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.7704 |
|
| 138 |
N |
L |
-1.5536 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.7643 |
|
| 142 |
R |
L |
-3.0850 |
|
| 143 |
E |
L |
-3.1579 |
|
| 144 |
A |
L |
-2.3751 |
|
| 145 |
K |
L |
-2.5496 |
|
| 146 |
V |
L |
-1.4465 |
|
| 147 |
Q |
L |
-0.6439 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.4265 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.5057 |
|
| 152 |
N |
L |
-1.3538 |
|
| 153 |
A |
L |
-0.1558 |
|
| 154 |
L |
L |
0.7399 |
|
| 155 |
Q |
L |
-0.2105 |
|
| 156 |
S |
L |
-0.6852 |
|
| 157 |
G |
L |
-1.1907 |
|
| 158 |
N |
L |
-1.3873 |
|
| 159 |
S |
L |
-1.6232 |
|
| 160 |
Q |
L |
-2.3643 |
|
| 161 |
E |
L |
-2.5190 |
|
| 162 |
S |
L |
-1.3036 |
|
| 163 |
V |
L |
-0.9590 |
|
| 164 |
T |
L |
-1.1477 |
|
| 165 |
E |
L |
-2.1523 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.3842 |
|
| 168 |
S |
L |
-2.2551 |
|
| 169 |
K |
L |
-2.6472 |
|
| 170 |
D |
L |
-2.0747 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-1.0619 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.5327 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.6558 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.7301 |
|
| 181 |
L |
L |
0.0000 |
|
| 182 |
S |
L |
-1.3222 |
|
| 183 |
K |
L |
-2.1276 |
|
| 184 |
A |
L |
-1.8749 |
|
| 185 |
D |
L |
-2.6036 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-2.7925 |
|
| 188 |
K |
L |
-3.3043 |
|
| 189 |
H |
L |
-2.8431 |
|
| 190 |
K |
L |
-3.0348 |
|
| 191 |
V |
L |
-1.3896 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.6170 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.1577 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.5053 |
|
| 200 |
G |
L |
-0.4339 |
|
| 201 |
L |
L |
-0.2146 |
|
| 202 |
S |
L |
-0.4214 |
|
| 203 |
S |
L |
-0.3591 |
|
| 204 |
P |
L |
-0.4387 |
|
| 205 |
V |
L |
0.1261 |
|
| 206 |
T |
L |
-0.3461 |
|
| 207 |
K |
L |
-0.4634 |
|
| 208 |
S |
L |
-0.3808 |
|
| 209 |
F |
L |
-0.8483 |
|
| 210 |
N |
L |
-2.0384 |
|
| 211 |
R |
L |
-2.4683 |
|
| 212 |
G |
L |
-2.1134 |
|
| 213 |
E |
L |
-2.5427 |
|