Project name: 4hix:L
Status: done
submitted: 2019-03-21 14:48:04, status changed: 2019-03-21 14:57:38
Settings
|
Chain sequence(s)
|
L: YVVMTQSPLSLPVTPGEPASISCKSSQSLLDSDGKTYLNWLLQKPGQSPQRLIYLVSKLDSGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCWQGTHFPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.4709
-
Maximal score value
-
1.6879
-
Average score
-
-0.8299
-
Total score value
-
-181.75
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Y |
L |
1.6879 |
|
| 2 |
V |
L |
0.0000 |
|
| 3 |
V |
L |
1.5498 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-0.2980 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.1274 |
|
| 8 |
P |
L |
0.3195 |
|
| 9 |
L |
L |
0.8885 |
|
| 10 |
S |
L |
0.1548 |
|
| 11 |
L |
L |
-0.1406 |
|
| 12 |
P |
L |
-0.7541 |
|
| 13 |
V |
L |
0.0000 |
|
| 14 |
T |
L |
-1.6923 |
|
| 15 |
P |
L |
-1.9542 |
|
| 16 |
G |
L |
-2.0228 |
|
| 17 |
E |
L |
-2.5752 |
|
| 18 |
P |
L |
-2.1800 |
|
| 19 |
A |
L |
0.0000 |
|
| 20 |
S |
L |
-0.6878 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
S |
L |
-0.8722 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
K |
L |
-2.0778 |
|
| 25 |
S |
L |
0.0000 |
|
| 26 |
S |
L |
-0.3235 |
|
| 27 |
Q |
L |
-0.6073 |
|
| 27A |
S |
L |
-0.6059 |
|
| 27B |
L |
L |
0.0000 |
|
| 27C |
L |
L |
0.2421 |
|
| 27D |
D |
L |
-1.2182 |
|
| 27E |
S |
L |
-1.4323 |
|
| 28 |
D |
L |
-2.4876 |
|
| 29 |
G |
L |
-1.8453 |
|
| 30 |
K |
L |
-1.7838 |
|
| 31 |
T |
L |
-0.4970 |
|
| 32 |
Y |
L |
0.0315 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
N |
L |
-0.0987 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
L |
L |
0.0000 |
|
| 37 |
L |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.4239 |
|
| 39 |
K |
L |
-1.7257 |
|
| 40 |
P |
L |
-1.2819 |
|
| 41 |
G |
L |
-1.3920 |
|
| 42 |
Q |
L |
-1.9465 |
|
| 43 |
S |
L |
-1.5517 |
|
| 44 |
P |
L |
-1.6045 |
|
| 45 |
Q |
L |
-2.2198 |
|
| 46 |
R |
L |
-1.8315 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
-0.1178 |
|
| 50 |
L |
L |
-0.0882 |
|
| 51 |
V |
L |
-0.2346 |
|
| 52 |
S |
L |
-0.7017 |
|
| 53 |
K |
L |
-1.2899 |
|
| 54 |
L |
L |
-1.0406 |
|
| 55 |
D |
L |
-1.0592 |
|
| 56 |
S |
L |
-0.8371 |
|
| 57 |
G |
L |
-0.9409 |
|
| 58 |
V |
L |
0.0000 |
|
| 59 |
P |
L |
-1.2114 |
|
| 60 |
D |
L |
-2.0454 |
|
| 61 |
R |
L |
-2.1347 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-1.2449 |
|
| 64 |
G |
L |
0.0000 |
|
| 65 |
S |
L |
-0.8161 |
|
| 66 |
G |
L |
-1.1292 |
|
| 67 |
S |
L |
-0.7722 |
|
| 68 |
G |
L |
-0.7604 |
|
| 69 |
T |
L |
-1.5418 |
|
| 70 |
D |
L |
-2.6325 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-1.0466 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
K |
L |
-1.4702 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-2.3497 |
|
| 77 |
R |
L |
-3.1463 |
|
| 78 |
V |
L |
0.0000 |
|
| 79 |
E |
L |
-2.7023 |
|
| 80 |
A |
L |
-2.4137 |
|
| 81 |
E |
L |
-2.6562 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
V |
L |
0.0000 |
|
| 84 |
G |
L |
0.0000 |
|
| 85 |
V |
L |
-0.2715 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
-0.0876 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
W |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
G |
L |
-0.5208 |
|
| 92 |
T |
L |
-0.5246 |
|
| 93 |
H |
L |
0.2870 |
|
| 94 |
F |
L |
1.2572 |
|
| 95 |
P |
L |
0.2474 |
|
| 96 |
R |
L |
-0.9432 |
|
| 97 |
T |
L |
0.1846 |
|
| 98 |
F |
L |
0.5406 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
Q |
L |
-0.5483 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-0.6815 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-1.1626 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.5088 |
|
| 108 |
R |
L |
-1.1493 |
|
| 109 |
T |
L |
-0.2142 |
|
| 110 |
V |
L |
0.1078 |
|
| 111 |
A |
L |
-0.2318 |
|
| 112 |
A |
L |
-0.2701 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1266 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.1103 |
|
| 117 |
I |
L |
1.1162 |
|
| 118 |
F |
L |
1.4284 |
|
| 119 |
P |
L |
-0.0137 |
|
| 120 |
P |
L |
0.0000 |
|
| 121 |
S |
L |
-1.7469 |
|
| 122 |
D |
L |
-3.2447 |
|
| 123 |
E |
L |
-3.4709 |
|
| 124 |
Q |
L |
-2.5297 |
|
| 125 |
L |
L |
-2.4477 |
|
| 126 |
K |
L |
-3.1316 |
|
| 127 |
S |
L |
-2.0169 |
|
| 128 |
G |
L |
-1.5994 |
|
| 129 |
T |
L |
-1.3638 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0425 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.6715 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.4530 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.6740 |
|
| 138 |
N |
L |
-1.3467 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.7803 |
|
| 142 |
R |
L |
-2.9093 |
|
| 143 |
E |
L |
-3.2206 |
|
| 144 |
A |
L |
-2.3349 |
|
| 145 |
K |
L |
-2.5062 |
|
| 146 |
V |
L |
-1.1698 |
|
| 147 |
Q |
L |
-0.8575 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.8681 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-2.0639 |
|
| 152 |
N |
L |
-1.4712 |
|
| 153 |
A |
L |
-0.4562 |
|
| 154 |
L |
L |
0.3414 |
|
| 155 |
Q |
L |
-0.3238 |
|
| 156 |
S |
L |
-0.5064 |
|
| 157 |
G |
L |
-0.9866 |
|
| 158 |
N |
L |
-0.9283 |
|
| 159 |
S |
L |
-1.4493 |
|
| 160 |
Q |
L |
-2.3053 |
|
| 161 |
E |
L |
-2.3580 |
|
| 162 |
S |
L |
-1.2671 |
|
| 163 |
V |
L |
-0.5401 |
|
| 164 |
T |
L |
-0.8118 |
|
| 165 |
E |
L |
-1.3059 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.2944 |
|
| 168 |
S |
L |
-2.3750 |
|
| 169 |
K |
L |
-2.8733 |
|
| 170 |
D |
L |
-2.1870 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.8510 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.5381 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.6701 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.4584 |
|
| 181 |
L |
L |
-0.5751 |
|
| 182 |
S |
L |
-0.9196 |
|
| 183 |
K |
L |
-1.9304 |
|
| 184 |
A |
L |
-1.6345 |
|
| 185 |
D |
L |
-2.0945 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.0176 |
|
| 188 |
K |
L |
-3.2939 |
|
| 189 |
H |
L |
-2.9577 |
|
| 190 |
K |
L |
-3.0157 |
|
| 191 |
V |
L |
-1.6882 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-1.0464 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.2563 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.7965 |
|
| 200 |
G |
L |
-0.4866 |
|
| 201 |
L |
L |
-0.2767 |
|
| 202 |
S |
L |
-0.4343 |
|
| 203 |
S |
L |
-0.4334 |
|
| 204 |
P |
L |
-0.5595 |
|
| 205 |
V |
L |
-0.0288 |
|
| 206 |
T |
L |
-0.4947 |
|
| 207 |
K |
L |
-0.5063 |
|
| 208 |
S |
L |
-0.4773 |
|
| 209 |
F |
L |
-0.8995 |
|
| 210 |
N |
L |
-2.2445 |
|
| 211 |
R |
L |
-2.5167 |
|
| 212 |
G |
L |
-2.1279 |
|
| 213 |
E |
L |
-2.1555 |
|
| 214 |
C |
L |
-1.4060 |
|