Project name: 3ixt:A

Chain sequence(s)	H: QVTLRESGPALVKPTQTLTLTCTFSGFSLSTAGMSVGWIRQPPGKALEWLADIWWDDKKHYNPSLKDRLTISKDTSKNQVVLKVTNMDPADTATYYCARDMIFNFYFDVWGQGTTVTVSSASTKGPSVFPLAPSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.329
• Maximal score value: 3.4168
• Average score: -0.4827
• Total score value: -102.8247

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.2112
2	V	H	-0.5901
3	T	H	-0.7818
4	L	H	0.0000
5	R	H	-2.0452
6	E	H	0.0000
7	S	H	-0.6311
8	G	H	-0.3071
9	P	H	-0.3632
10	A	H	-0.4120
11	L	H	-0.2797
12	V	H	0.0000
13	K	H	-2.2978
14	P	H	-1.9808
15	T	H	-1.9340
16	Q	H	-2.1506
17	T	H	-1.5181
18	L	H	0.0000
19	T	H	-0.4867
20	L	H	0.0000
21	T	H	-0.4908
22	C	H	0.0000
23	T	H	-1.1487
24	F	H	0.0000
25	S	H	-0.9393
26	G	H	-0.7524
27	F	H	-0.2737
28	S	H	-0.3697
29	L	H	0.0000
30	S	H	-0.6883
31	T	H	-0.1861
32	A	H	0.0485
33	G	H	0.0000
34	M	H	0.6315
35	S	H	0.0000
35A	V	H	0.0000
35B	G	H	0.0000
36	W	H	0.0000
37	I	H	0.0000
38	R	H	0.0000
39	Q	H	-0.7032
40	P	H	0.0000
41	P	H	-1.1327
42	G	H	-1.3768
43	K	H	-1.9059
44	A	H	-0.5867
45	L	H	0.4349
46	E	H	-0.0416
47	W	H	0.3724
48	L	H	0.0000
49	A	H	0.0000
50	D	H	0.0000
51	I	H	0.0000
52	W	H	0.0000
53	W	H	-1.4007
54	D	H	-2.9293
55	D	H	-3.3290
56	K	H	-3.3010
57	K	H	-2.1808
58	H	H	-0.9510
59	Y	H	-0.5747
60	N	H	-0.7032
61	P	H	-1.0355
62	S	H	-0.8677
63	L	H	0.0000
64	K	H	-2.0575
65	D	H	-2.4443
66	R	H	-1.9430
67	L	H	0.0000
68	T	H	-0.8115
69	I	H	0.0000
70	S	H	-0.9881
71	K	H	-1.1838
72	D	H	-1.4210
73	T	H	-1.1990
74	S	H	-1.4313
75	K	H	-2.2475
76	N	H	-1.5960
77	Q	H	-1.4043
78	V	H	0.0000
79	V	H	-0.1819
80	L	H	0.0000
81	K	H	-0.8114
82	V	H	0.0000
82A	T	H	-1.7579
82B	N	H	-2.2405
82C	M	H	0.0000
83	D	H	-2.1457
84	P	H	-1.1305
85	A	H	-0.5582
86	D	H	0.0000
87	T	H	-0.4374
88	A	H	0.0000
89	T	H	-0.2451
90	Y	H	0.0000
91	Y	H	-0.2372
92	C	H	0.0000
93	A	H	0.0000
94	R	H	0.0000
95	D	H	0.0000
96	M	H	2.3475
97	I	H	3.2950
98	F	H	3.2681
99	N	H	2.6046
100	F	H	3.4168
100A	Y	H	2.6585
100B	F	H	1.1790
101	D	H	0.1022
102	V	H	0.1050
103	W	H	-0.0111
104	G	H	-0.8999
105	Q	H	-1.5083
106	G	H	-0.9750
107	T	H	-0.6570
108	T	H	-0.3623
109	V	H	0.0000
110	T	H	-0.5065
111	V	H	0.0000
112	S	H	-0.9114
113	S	H	-0.7923
114	A	H	-0.5755
115	S	H	-0.7529
116	T	H	-0.8780
117	K	H	-1.6494
118	G	H	-1.7828
119	P	H	-0.8649
120	S	H	-0.2905
121	V	H	0.0000
122	F	H	0.8815
123	P	H	-0.0523
124	L	H	0.4727
125	A	H	-0.4942
126	P	H	0.0000
127	S	H	-0.4096
135	T	H	-0.2697
136	A	H	-0.1887
137	A	H	0.0718
138	L	H	0.0000
139	G	H	0.0000
140	C	H	0.0000
141	L	H	0.6338
142	V	H	0.0000
143	K	H	-0.3985
144	D	H	-1.0079
145	Y	H	0.0000
146	F	H	0.0000
147	P	H	0.0000
148	E	H	-0.6504
149	P	H	-0.6906
150	V	H	-0.6179
151	T	H	-0.4997
152	V	H	-0.0754
153	S	H	-0.3465
154	W	H	0.0000
155	N	H	-0.8629
156	S	H	-0.7056
157	G	H	-0.5467
158	A	H	-0.2557
159	L	H	-0.0407
160	T	H	-0.3115
161	S	H	-0.4196
162	G	H	-0.4963
163	V	H	-0.0286
164	H	H	-0.4357
165	T	H	0.1703
166	F	H	1.0617
167	P	H	0.7717
168	A	H	1.3088
169	V	H	2.5556
170	L	H	2.1941
171	Q	H	0.6903
172	S	H	0.1065
173	S	H	-0.2534
174	G	H	0.1535
175	L	H	0.1517
176	Y	H	0.7334
177	S	H	0.0000
178	L	H	0.0000
179	S	H	0.6515
180	S	H	0.0000
181	V	H	0.4206
182	V	H	0.0000
183	T	H	-0.2423
184	V	H	0.0000
185	P	H	-0.5212
186	S	H	-0.4748
187	S	H	-0.5656
188	S	H	-0.6517
189	L	H	-0.8958
190	G	H	-1.1878
191	T	H	-0.9564
192	Q	H	-1.4153
193	T	H	-1.2310
194	Y	H	0.0000
195	I	H	-1.3608
196	C	H	0.0000
197	N	H	-1.5592
198	V	H	0.0000
199	N	H	-1.7733
200	H	H	0.0000
201	K	H	-2.7509
202	P	H	-1.6059
203	S	H	-1.9199
204	N	H	-2.5301
205	T	H	-2.1488
206	K	H	-2.6788
207	V	H	-1.7560
208	D	H	-2.7439
209	K	H	-2.1973
210	K	H	-2.6337
211	V	H	0.0000
212	E	H	-2.5326
213	P	H	-1.1779