Project name: 3ixt:L
Status: done
submitted: 2019-03-20 20:11:09, status changed: 2019-03-20 20:24:56
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSTLSASVGDRVTITCSASSRVGYMHWYQQKPGKAPKLLIYDTSKLASGVPSRFSGSGSGTEFTLTISSLQPDDFATYYCFQGSGYPFTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.8527
-
Maximal score value
-
1.5601
-
Average score
-
-0.7683
-
Total score value
-
-162.1145
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.6194 |
|
| 2 |
I |
L |
-1.1108 |
|
| 3 |
Q |
L |
-1.3211 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-0.6682 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.6346 |
|
| 8 |
P |
L |
-0.6292 |
|
| 9 |
S |
L |
-0.8757 |
|
| 10 |
T |
L |
-0.9057 |
|
| 11 |
L |
L |
-0.6664 |
|
| 12 |
S |
L |
-0.7578 |
|
| 13 |
A |
L |
-0.9042 |
|
| 14 |
S |
L |
-0.7927 |
|
| 15 |
V |
L |
0.0537 |
|
| 16 |
G |
L |
-0.8406 |
|
| 17 |
D |
L |
-1.8781 |
|
| 18 |
R |
L |
-2.3253 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6191 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.6092 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
S |
L |
-1.3925 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-1.4879 |
|
| 27 |
S |
L |
-1.7974 |
|
| 29 |
R |
L |
-2.2427 |
|
| 30 |
V |
L |
0.0000 |
|
| 31 |
G |
L |
-0.4922 |
|
| 32 |
Y |
L |
0.5690 |
|
| 33 |
M |
L |
0.0000 |
|
| 34 |
H |
L |
0.4281 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
0.2223 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.1946 |
|
| 39 |
K |
L |
0.0000 |
|
| 40 |
P |
L |
-1.3296 |
|
| 41 |
G |
L |
-1.5814 |
|
| 42 |
K |
L |
-2.2191 |
|
| 43 |
A |
L |
-1.2912 |
|
| 44 |
P |
L |
-1.1694 |
|
| 45 |
K |
L |
-1.3800 |
|
| 46 |
L |
L |
0.0329 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
0.3042 |
|
| 50 |
D |
L |
-0.3064 |
|
| 51 |
T |
L |
-0.2746 |
|
| 52 |
S |
L |
-0.7299 |
|
| 53 |
K |
L |
-1.2101 |
|
| 54 |
L |
L |
-0.1211 |
|
| 55 |
A |
L |
-0.1808 |
|
| 56 |
S |
L |
-0.3114 |
|
| 57 |
G |
L |
-0.3640 |
|
| 58 |
V |
L |
-0.1548 |
|
| 59 |
P |
L |
-0.2975 |
|
| 60 |
S |
L |
-0.3420 |
|
| 61 |
R |
L |
-0.6891 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.4635 |
|
| 64 |
G |
L |
-0.5840 |
|
| 65 |
S |
L |
-0.8587 |
|
| 66 |
G |
L |
-1.0241 |
|
| 67 |
S |
L |
-1.1432 |
|
| 68 |
G |
L |
-1.4398 |
|
| 69 |
T |
L |
-1.7439 |
|
| 70 |
E |
L |
-2.3925 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.7023 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.5842 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.3177 |
|
| 77 |
S |
L |
-1.1357 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-1.2795 |
|
| 80 |
P |
L |
-1.9858 |
|
| 81 |
D |
L |
-2.6162 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
-1.4932 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
0.0000 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.3189 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
F |
L |
1.1619 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
G |
L |
0.6714 |
|
| 92 |
S |
L |
0.0670 |
|
| 93 |
G |
L |
0.0652 |
|
| 94 |
Y |
L |
1.1069 |
|
| 95 |
P |
L |
0.5710 |
|
| 96 |
F |
L |
1.4626 |
|
| 97 |
T |
L |
0.8814 |
|
| 98 |
F |
L |
1.3498 |
|
| 99 |
G |
L |
0.1406 |
|
| 100 |
G |
L |
-0.5801 |
|
| 101 |
G |
L |
-0.5113 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-1.9009 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-1.3304 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.1026 |
|
| 108 |
R |
L |
-0.7124 |
|
| 109 |
T |
L |
-0.1654 |
|
| 110 |
V |
L |
0.2131 |
|
| 111 |
A |
L |
-0.2191 |
|
| 112 |
A |
L |
-0.2751 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1367 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.3222 |
|
| 117 |
I |
L |
1.3611 |
|
| 118 |
F |
L |
1.5601 |
|
| 119 |
P |
L |
-0.0402 |
|
| 120 |
P |
L |
-0.6816 |
|
| 121 |
S |
L |
-1.7423 |
|
| 122 |
D |
L |
-3.2002 |
|
| 123 |
E |
L |
-3.4057 |
|
| 124 |
Q |
L |
-2.4871 |
|
| 125 |
L |
L |
-2.5362 |
|
| 126 |
K |
L |
-3.0320 |
|
| 127 |
S |
L |
-1.9356 |
|
| 128 |
G |
L |
-1.4374 |
|
| 129 |
T |
L |
-1.2501 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0370 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7597 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.6603 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.5844 |
|
| 138 |
N |
L |
-1.3258 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.8080 |
|
| 142 |
R |
L |
-2.9506 |
|
| 143 |
E |
L |
-3.2945 |
|
| 144 |
A |
L |
-2.2967 |
|
| 145 |
K |
L |
-2.3259 |
|
| 146 |
V |
L |
-1.2068 |
|
| 147 |
Q |
L |
-0.8016 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.7638 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.8707 |
|
| 152 |
N |
L |
-1.4296 |
|
| 153 |
A |
L |
-0.3557 |
|
| 154 |
L |
L |
0.5433 |
|
| 155 |
Q |
L |
-0.1960 |
|
| 156 |
S |
L |
-0.4697 |
|
| 157 |
G |
L |
-0.9942 |
|
| 158 |
N |
L |
-0.9300 |
|
| 159 |
S |
L |
-1.4090 |
|
| 160 |
Q |
L |
-2.2192 |
|
| 161 |
E |
L |
-2.1213 |
|
| 162 |
S |
L |
-1.1580 |
|
| 163 |
V |
L |
-0.5602 |
|
| 164 |
T |
L |
-1.1657 |
|
| 165 |
E |
L |
-2.2027 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.4098 |
|
| 168 |
S |
L |
-2.4977 |
|
| 169 |
K |
L |
-2.9035 |
|
| 170 |
D |
L |
-2.3569 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.9039 |
|
| 175 |
L |
L |
-0.6240 |
|
| 176 |
S |
L |
-0.3368 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.5750 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.5188 |
|
| 181 |
L |
L |
-0.7867 |
|
| 182 |
S |
L |
-1.3703 |
|
| 183 |
K |
L |
-2.3795 |
|
| 184 |
A |
L |
-2.0534 |
|
| 185 |
D |
L |
-2.7028 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.8527 |
|
| 188 |
K |
L |
-3.7416 |
|
| 189 |
H |
L |
-3.1849 |
|
| 190 |
K |
L |
-3.2964 |
|
| 191 |
V |
L |
-1.8554 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
-0.9461 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.8860 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.2885 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.8173 |
|
| 200 |
G |
L |
-0.4650 |
|
| 201 |
L |
L |
-0.2771 |
|
| 202 |
S |
L |
-0.4677 |
|
| 203 |
S |
L |
-0.4412 |
|
| 204 |
P |
L |
-0.6064 |
|
| 205 |
V |
L |
-0.1281 |
|
| 206 |
T |
L |
-0.4432 |
|
| 207 |
K |
L |
-0.2787 |
|
| 208 |
S |
L |
-0.4286 |
|
| 209 |
F |
L |
-0.8363 |
|
| 210 |
N |
L |
-2.2729 |
|
| 211 |
R |
L |
-2.7865 |
|
| 212 |
G |
L |
-1.6539 |
|