Project name: 5f88:B
Status: done
submitted: 2019-03-20 15:51:55, status changed: 2019-03-20 17:24:50
Settings
|
Chain sequence(s)
|
B: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.8763
-
Maximal score value
-
2.4848
-
Average score
-
-0.548
-
Total score value
-
-118.3751
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
B |
-1.4567 |
|
| 2 |
V |
B |
-0.8011 |
|
| 3 |
Q |
B |
-1.8197 |
|
| 4 |
L |
B |
0.0000 |
|
| 5 |
K |
B |
-2.3568 |
|
| 6 |
Q |
B |
0.0000 |
|
| 7 |
S |
B |
-0.8924 |
|
| 8 |
G |
B |
-1.2618 |
|
| 9 |
P |
B |
-0.5707 |
|
| 10 |
G |
B |
-0.4923 |
|
| 11 |
L |
B |
-0.0933 |
|
| 12 |
V |
B |
-0.7784 |
|
| 13 |
Q |
B |
-1.4976 |
|
| 14 |
P |
B |
-1.4620 |
|
| 15 |
S |
B |
-1.5599 |
|
| 16 |
Q |
B |
-1.9220 |
|
| 17 |
S |
B |
-1.9312 |
|
| 18 |
L |
B |
0.0000 |
|
| 19 |
S |
B |
-0.9150 |
|
| 20 |
I |
B |
0.0000 |
|
| 21 |
T |
B |
-0.6385 |
|
| 22 |
C |
B |
0.0000 |
|
| 23 |
T |
B |
-1.2365 |
|
| 24 |
V |
B |
0.0000 |
|
| 25 |
S |
B |
-1.1363 |
|
| 26 |
G |
B |
-0.9870 |
|
| 27 |
F |
B |
-0.5358 |
|
| 28 |
S |
B |
-0.8538 |
|
| 29 |
L |
B |
0.0000 |
|
| 30 |
T |
B |
-0.8865 |
|
| 31 |
N |
B |
-0.8549 |
|
| 32 |
Y |
B |
0.3801 |
|
| 33 |
G |
B |
0.0000 |
|
| 34 |
V |
B |
0.0000 |
|
| 35 |
H |
B |
0.0000 |
|
| 36 |
W |
B |
0.0000 |
|
| 37 |
V |
B |
0.0000 |
|
| 38 |
R |
B |
0.0000 |
|
| 39 |
Q |
B |
-0.1979 |
|
| 40 |
S |
B |
-0.8715 |
|
| 41 |
P |
B |
-1.1064 |
|
| 42 |
G |
B |
-1.6727 |
|
| 43 |
K |
B |
-1.9969 |
|
| 44 |
G |
B |
-0.5988 |
|
| 45 |
L |
B |
0.8229 |
|
| 46 |
E |
B |
0.0000 |
|
| 47 |
W |
B |
0.4640 |
|
| 48 |
L |
B |
0.0000 |
|
| 49 |
G |
B |
0.0000 |
|
| 50 |
V |
B |
0.0000 |
|
| 51 |
I |
B |
0.0000 |
|
| 52 |
W |
B |
-0.5665 |
|
| 53 |
S |
B |
-0.6195 |
|
| 54 |
G |
B |
-1.2064 |
|
| 55 |
G |
B |
-1.5021 |
|
| 56 |
N |
B |
-1.9446 |
|
| 57 |
T |
B |
-1.5182 |
|
| 58 |
D |
B |
-1.5464 |
|
| 59 |
Y |
B |
-0.6785 |
|
| 60 |
N |
B |
-0.6414 |
|
| 61 |
T |
B |
-0.5248 |
|
| 62 |
P |
B |
-0.4668 |
|
| 63 |
F |
B |
0.0000 |
|
| 64 |
T |
B |
-0.5996 |
|
| 65 |
S |
B |
-0.7060 |
|
| 66 |
R |
B |
-1.2953 |
|
| 67 |
L |
B |
0.0000 |
|
| 68 |
S |
B |
-1.3282 |
|
| 69 |
I |
B |
0.0000 |
|
| 70 |
N |
B |
-1.8349 |
|
| 71 |
K |
B |
-1.4836 |
|
| 72 |
D |
B |
-1.8007 |
|
| 73 |
N |
B |
-2.1536 |
|
| 74 |
S |
B |
-1.6560 |
|
| 75 |
K |
B |
-2.3385 |
|
| 76 |
S |
B |
-1.5639 |
|
| 77 |
Q |
B |
-1.5408 |
|
| 78 |
V |
B |
0.0000 |
|
| 79 |
F |
B |
-0.5246 |
|
| 80 |
F |
B |
0.0000 |
|
| 81 |
K |
B |
-2.0850 |
|
| 82 |
M |
B |
0.0000 |
|
| 83 |
N |
B |
-2.3329 |
|
| 84 |
S |
B |
-1.6513 |
|
| 85 |
L |
B |
0.0000 |
|
| 86 |
Q |
B |
-2.0337 |
|
| 87 |
S |
B |
-1.4715 |
|
| 88 |
N |
B |
-2.0380 |
|
| 89 |
D |
B |
0.0000 |
|
| 90 |
T |
B |
-0.6469 |
|
| 91 |
A |
B |
0.0000 |
|
| 92 |
I |
B |
0.6332 |
|
| 93 |
Y |
B |
0.0000 |
|
| 94 |
Y |
B |
-0.0823 |
|
| 95 |
C |
B |
0.0000 |
|
| 96 |
A |
B |
0.0000 |
|
| 97 |
R |
B |
0.0000 |
|
| 98 |
A |
B |
0.0000 |
|
| 99 |
L |
B |
1.1218 |
|
| 100 |
T |
B |
1.0204 |
|
| 101 |
Y |
B |
1.6496 |
|
| 102 |
Y |
B |
1.5745 |
|
| 103 |
D |
B |
0.3704 |
|
| 104 |
Y |
B |
0.4137 |
|
| 105 |
E |
B |
-0.7807 |
|
| 106 |
F |
B |
0.1253 |
|
| 107 |
A |
B |
0.4714 |
|
| 108 |
Y |
B |
0.3530 |
|
| 109 |
W |
B |
0.0378 |
|
| 110 |
G |
B |
0.0000 |
|
| 111 |
Q |
B |
-1.5626 |
|
| 112 |
G |
B |
-0.6780 |
|
| 113 |
T |
B |
0.0000 |
|
| 114 |
L |
B |
0.2096 |
|
| 115 |
V |
B |
0.0000 |
|
| 116 |
T |
B |
-0.3036 |
|
| 117 |
V |
B |
0.0000 |
|
| 118 |
S |
B |
-0.6693 |
|
| 119 |
A |
B |
-0.3520 |
|
| 120 |
A |
B |
-0.3172 |
|
| 121 |
S |
B |
-0.5145 |
|
| 122 |
T |
B |
-0.7690 |
|
| 123 |
K |
B |
-1.2665 |
|
| 124 |
G |
B |
-1.4353 |
|
| 125 |
P |
B |
-0.6124 |
|
| 126 |
S |
B |
-0.1401 |
|
| 127 |
V |
B |
0.0000 |
|
| 128 |
F |
B |
0.7680 |
|
| 129 |
P |
B |
-0.2000 |
|
| 130 |
L |
B |
0.3202 |
|
| 131 |
A |
B |
-0.9370 |
|
| 132 |
P |
B |
0.0000 |
|
| 133 |
S |
B |
-0.7466 |
|
| 138 |
S |
B |
-0.6596 |
|
| 139 |
G |
B |
-0.8589 |
|
| 140 |
G |
B |
-0.9399 |
|
| 141 |
T |
B |
-0.6585 |
|
| 142 |
A |
B |
-0.3979 |
|
| 143 |
A |
B |
0.0698 |
|
| 144 |
L |
B |
0.0000 |
|
| 145 |
G |
B |
0.0000 |
|
| 146 |
C |
B |
0.0000 |
|
| 147 |
L |
B |
0.6414 |
|
| 148 |
V |
B |
0.0000 |
|
| 149 |
K |
B |
-0.2385 |
|
| 150 |
D |
B |
-0.6111 |
|
| 151 |
Y |
B |
0.0000 |
|
| 152 |
F |
B |
0.0000 |
|
| 153 |
P |
B |
0.0000 |
|
| 154 |
E |
B |
-0.1109 |
|
| 155 |
P |
B |
-0.5289 |
|
| 156 |
V |
B |
-0.5906 |
|
| 157 |
T |
B |
-0.5202 |
|
| 158 |
V |
B |
-0.1845 |
|
| 159 |
S |
B |
-0.4601 |
|
| 160 |
W |
B |
0.0000 |
|
| 161 |
N |
B |
-0.9391 |
|
| 162 |
S |
B |
-0.6788 |
|
| 163 |
G |
B |
-0.5398 |
|
| 164 |
A |
B |
-0.2343 |
|
| 165 |
L |
B |
-0.0375 |
|
| 166 |
T |
B |
-0.3090 |
|
| 167 |
S |
B |
-0.3805 |
|
| 168 |
G |
B |
-0.4778 |
|
| 169 |
V |
B |
-0.0222 |
|
| 170 |
H |
B |
-0.5023 |
|
| 171 |
T |
B |
0.1073 |
|
| 172 |
F |
B |
0.8070 |
|
| 173 |
P |
B |
0.6694 |
|
| 174 |
A |
B |
1.2569 |
|
| 175 |
V |
B |
2.4848 |
|
| 176 |
L |
B |
2.1809 |
|
| 177 |
Q |
B |
0.6917 |
|
| 178 |
S |
B |
0.0796 |
|
| 179 |
S |
B |
-0.2265 |
|
| 180 |
G |
B |
0.1789 |
|
| 181 |
L |
B |
0.2927 |
|
| 182 |
Y |
B |
0.8979 |
|
| 183 |
S |
B |
0.0000 |
|
| 184 |
L |
B |
0.0000 |
|
| 185 |
S |
B |
0.5919 |
|
| 186 |
S |
B |
0.0000 |
|
| 187 |
V |
B |
0.4556 |
|
| 188 |
V |
B |
0.0000 |
|
| 189 |
T |
B |
-0.2067 |
|
| 190 |
V |
B |
0.0000 |
|
| 191 |
P |
B |
-0.5848 |
|
| 192 |
S |
B |
-0.6467 |
|
| 193 |
S |
B |
-0.6415 |
|
| 194 |
S |
B |
-0.6890 |
|
| 195 |
L |
B |
-0.8597 |
|
| 196 |
G |
B |
-0.9972 |
|
| 197 |
T |
B |
-0.7838 |
|
| 198 |
Q |
B |
-1.3159 |
|
| 199 |
T |
B |
-1.2144 |
|
| 200 |
Y |
B |
0.0000 |
|
| 201 |
I |
B |
-1.4860 |
|
| 202 |
C |
B |
0.0000 |
|
| 203 |
N |
B |
-1.5057 |
|
| 204 |
V |
B |
0.0000 |
|
| 205 |
N |
B |
-1.8117 |
|
| 206 |
H |
B |
0.0000 |
|
| 207 |
K |
B |
-2.7947 |
|
| 208 |
P |
B |
-1.5997 |
|
| 209 |
S |
B |
-1.8125 |
|
| 210 |
N |
B |
-2.5290 |
|
| 211 |
T |
B |
-2.0181 |
|
| 212 |
K |
B |
-2.6555 |
|
| 213 |
V |
B |
-1.7126 |
|
| 214 |
D |
B |
-2.6252 |
|
| 215 |
K |
B |
-2.2093 |
|
| 216 |
R |
B |
-2.6939 |
|
| 217 |
V |
B |
0.0000 |
|
| 218 |
E |
B |
-2.8763 |
|
| 219 |
P |
B |
-1.8508 |
|
| 220 |
K |
B |
-2.2370 |
|