Project name: 5u6a:B

Chain sequence(s)	B: EVQLVESGGGLVQPGGSLRLSSCAASGFNNIKDTYIHWVRQSPGKGLEWVARIYPTTNGYTRYADSVKKGRFTISADTSKNTAYLQMMNSLRRAEDTAIYYCSRWGGDGFYAMDYWGQGTLVTVSSSASTKGPSVFPLAPSSKKSTSGGTAALGCLVKKDYFPEEPVTVSWNSGALTSSGVHTFPAVLQSSGLYSSLSSVVTTVPSSSSLGTQTYICNVNNHKPSNTKVDKKKVEPKSC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8455
• Maximal score value: 2.4918
• Average score: -0.5681
• Total score value: -126.6813

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	B	-2.0599
2	V	B	-1.1849
3	Q	B	-1.0654
4	L	B	0.0000
5	V	B	0.3595
6	E	B	0.0000
7	S	B	-0.5664
8	G	B	-0.9375
9	G	B	-0.5274
10	G	B	-0.5243
11	L	B	-0.1461
12	V	B	0.0000
13	Q	B	-1.6880
14	P	B	-1.7972
15	G	B	-1.4653
16	G	B	-1.1636
17	S	B	-1.1355
18	L	B	-1.1159
19	R	B	-1.9708
20	L	B	0.0000
21	S	B	-0.4493
22	C	B	0.0000
23	A	B	-0.2636
24	A	B	0.0000
25	S	B	-1.1360
26	G	B	-1.3561
27	F	B	-1.4115
28	N	B	-1.8513
29	I	B	0.0000
30	K	B	-2.3714
31	D	B	-2.6659
32	T	B	0.0000
33	Y	B	-0.0180
34	I	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.4550
40	S	B	-1.0823
41	P	B	-1.1334
42	G	B	-1.7374
43	K	B	-2.2024
44	G	B	-0.7531
45	L	B	0.5808
46	E	B	-0.1304
47	W	B	0.3010
48	V	B	0.0000
49	A	B	0.0000
50	R	B	-0.9520
51	I	B	0.0000
52	Y	B	-0.4604
53	P	B	-1.0411
54	T	B	-1.1937
55	N	B	-1.1006
56	G	B	-0.4863
57	Y	B	0.3533
58	T	B	-0.6474
59	R	B	-2.1252
60	Y	B	-1.8632
61	A	B	-1.7523
62	D	B	-2.6367
63	S	B	-1.7655
64	V	B	0.0000
65	K	B	-2.8455
66	G	B	-1.7729
67	R	B	-1.3871
68	F	B	0.0000
69	T	B	-1.1233
70	I	B	0.0000
71	S	B	-0.1524
72	A	B	-0.6651
73	D	B	-1.1923
74	T	B	-1.3835
75	S	B	-1.4361
76	K	B	-2.1359
77	N	B	-1.6154
78	T	B	-0.8273
79	A	B	0.0000
80	Y	B	-0.4135
81	L	B	0.0000
82	Q	B	-1.0953
83	M	B	0.0000
84	N	B	-1.4209
85	S	B	-1.2512
86	L	B	0.0000
87	R	B	-2.4739
88	A	B	-1.8085
89	E	B	-2.6533
90	D	B	0.0000
91	T	B	-0.8802
92	A	B	0.0000
93	I	B	0.3847
94	Y	B	0.0000
95	Y	B	0.1791
96	C	B	0.0000
97	S	B	0.0000
98	R	B	0.0000
99	W	B	0.6735
100	G	B	0.3763
101	G	B	0.0000
102	D	B	-1.5002
103	G	B	-0.2292
104	F	B	1.7630
105	Y	B	1.9167
106	A	B	1.3030
107	M	B	1.0060
108	D	B	0.4424
109	Y	B	0.4553
110	W	B	0.4281
111	G	B	-0.1507
112	Q	B	-0.8660
113	G	B	-0.2670
114	T	B	-0.0557
115	L	B	0.0775
116	V	B	0.0000
117	T	B	-0.4608
118	V	B	0.0000
119	S	B	-0.8221
120	S	B	-0.7280
121	A	B	-0.4453
122	S	B	-0.5367
123	T	B	-0.5733
124	K	B	-1.1342
125	G	B	-1.4454
126	P	B	-0.6293
127	S	B	-0.1252
128	V	B	0.0000
129	F	B	1.0741
130	P	B	0.2135
131	L	B	0.3572
132	A	B	-1.0220
133	P	B	0.0000
134	S	B	-1.3108
135	S	B	-1.1480
136	K	B	-1.8937
137	S	B	-0.9944
138	T	B	-0.9929
139	S	B	-0.9455
140	G	B	-0.8556
141	G	B	-0.9158
142	T	B	-0.6364
143	A	B	0.0000
144	A	B	-0.1762
145	L	B	0.0000
146	G	B	0.0000
147	C	B	0.0000
148	L	B	0.6540
149	V	B	0.0000
150	K	B	-0.3480
151	D	B	-0.5594
152	Y	B	0.0000
153	F	B	0.0000
154	P	B	0.0000
155	E	B	-0.5939
156	P	B	-0.6973
157	V	B	-0.6312
158	T	B	-0.5084
159	V	B	-0.1530
160	S	B	-0.3408
161	W	B	0.0000
162	N	B	-0.7496
163	S	B	-0.6578
164	G	B	-0.4853
165	A	B	-0.2305
166	L	B	-0.0189
167	T	B	-0.2837
168	S	B	-0.3601
169	G	B	-0.4579
170	V	B	0.0324
171	H	B	-0.4051
172	T	B	0.1863
173	F	B	1.0086
174	P	B	0.7462
175	A	B	1.3050
176	V	B	2.4918
177	L	B	2.2210
178	Q	B	0.7236
179	S	B	0.1085
180	S	B	-0.2215
181	G	B	0.2013
182	L	B	0.2622
183	Y	B	0.8475
184	S	B	0.0000
185	L	B	0.0000
186	S	B	0.6527
187	S	B	0.0000
188	V	B	0.4181
189	V	B	0.0000
190	T	B	-0.2367
191	V	B	0.0000
192	P	B	-0.6168
193	S	B	-0.5429
194	S	B	-0.5241
195	S	B	-0.4989
196	L	B	-0.6796
197	G	B	-1.0340
198	T	B	-0.6663
199	Q	B	-1.1716
200	T	B	-1.0305
201	Y	B	0.0000
202	I	B	-1.2941
203	C	B	0.0000
204	N	B	-1.4583
205	V	B	0.0000
206	N	B	-1.7989
207	H	B	0.0000
208	K	B	-2.7610
209	P	B	-1.5983
210	S	B	-1.8261
211	N	B	-2.5621
212	T	B	-2.0628
213	K	B	-2.7223
214	V	B	-1.7760
215	D	B	-2.5814
216	K	B	-2.0750
217	K	B	-2.2876
218	V	B	0.0000
219	E	B	-2.7834
220	P	B	-1.8289
221	K	B	-2.0962
222	S	B	-0.9470
223	C	B	0.1614