Project name: 5j13:B
Status: done
submitted: 2019-03-21 13:05:37, status changed: 2019-03-21 13:18:35
Settings
|
Chain sequence(s)
|
B: SYVLTQPPSVSVAPGQTARITCGGNNLGSKSVHWYQQKPGQAPVLVVYDDSDRPSWIPERFSGSNSGNTATLTISRGEAGDEADYYCQVWDSSSDHVVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTEC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.1767
-
Maximal score value
-
2.2394
-
Average score
-
-0.8128
-
Total score value
-
-173.1216
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 4 |
S |
B |
-0.1250 |
|
| 5 |
Y |
B |
0.7894 |
|
| 6 |
V |
B |
1.7448 |
|
| 7 |
L |
B |
0.0000 |
|
| 8 |
T |
B |
0.2004 |
|
| 9 |
Q |
B |
0.0000 |
|
| 10 |
P |
B |
-0.4709 |
|
| 11 |
P |
B |
-0.6461 |
|
| 12 |
S |
B |
-0.4671 |
|
| 13 |
V |
B |
-0.4400 |
|
| 14 |
S |
B |
-0.6579 |
|
| 15 |
V |
B |
0.0000 |
|
| 16 |
A |
B |
-1.0564 |
|
| 17 |
P |
B |
-1.6363 |
|
| 18 |
G |
B |
-2.1678 |
|
| 19 |
Q |
B |
-2.5293 |
|
| 20 |
T |
B |
-2.0571 |
|
| 21 |
A |
B |
0.0000 |
|
| 22 |
R |
B |
-1.9731 |
|
| 23 |
I |
B |
0.0000 |
|
| 24 |
T |
B |
-0.5578 |
|
| 25 |
C |
B |
0.0000 |
|
| 26 |
G |
B |
-0.8764 |
|
| 27 |
G |
B |
-1.1800 |
|
| 28 |
N |
B |
-2.1871 |
|
| 29 |
N |
B |
-2.7793 |
|
| 30 |
L |
B |
0.0000 |
|
| 31 |
G |
B |
-1.9440 |
|
| 32 |
S |
B |
-1.3842 |
|
| 33 |
K |
B |
-1.1862 |
|
| 34 |
S |
B |
-1.0200 |
|
| 35 |
V |
B |
0.0000 |
|
| 36 |
H |
B |
-0.5876 |
|
| 37 |
W |
B |
0.0000 |
|
| 38 |
Y |
B |
0.5944 |
|
| 39 |
Q |
B |
-0.3803 |
|
| 40 |
Q |
B |
-1.1253 |
|
| 41 |
K |
B |
-1.5719 |
|
| 42 |
P |
B |
-1.3618 |
|
| 43 |
G |
B |
-1.3577 |
|
| 44 |
Q |
B |
-1.6563 |
|
| 45 |
A |
B |
-0.7313 |
|
| 46 |
P |
B |
-0.3260 |
|
| 47 |
V |
B |
0.6628 |
|
| 48 |
L |
B |
0.8395 |
|
| 49 |
V |
B |
0.0000 |
|
| 50 |
V |
B |
0.0000 |
|
| 51 |
Y |
B |
-1.3470 |
|
| 52 |
D |
B |
-2.5474 |
|
| 53 |
D |
B |
-2.0332 |
|
| 54 |
S |
B |
-1.8472 |
|
| 55 |
D |
B |
-2.4763 |
|
| 56 |
R |
B |
-1.8566 |
|
| 57 |
P |
B |
0.0000 |
|
| 58 |
S |
B |
-0.1380 |
|
| 59 |
W |
B |
0.8766 |
|
| 60 |
I |
B |
0.1008 |
|
| 61 |
P |
B |
-0.9392 |
|
| 62 |
E |
B |
-2.0721 |
|
| 63 |
R |
B |
-1.9228 |
|
| 64 |
F |
B |
0.0000 |
|
| 65 |
S |
B |
-1.3070 |
|
| 66 |
G |
B |
0.0000 |
|
| 67 |
S |
B |
-1.0265 |
|
| 68 |
N |
B |
-1.3409 |
|
| 69 |
S |
B |
-1.3633 |
|
| 70 |
G |
B |
-1.9719 |
|
| 71 |
N |
B |
-2.6412 |
|
| 72 |
T |
B |
-1.4926 |
|
| 73 |
A |
B |
0.0000 |
|
| 74 |
T |
B |
-0.7390 |
|
| 75 |
L |
B |
0.0000 |
|
| 76 |
T |
B |
-1.1125 |
|
| 77 |
I |
B |
0.0000 |
|
| 78 |
S |
B |
-2.2662 |
|
| 79 |
R |
B |
-3.0051 |
|
| 80 |
G |
B |
0.0000 |
|
| 81 |
E |
B |
-2.8558 |
|
| 82 |
A |
B |
-1.4865 |
|
| 83 |
G |
B |
-1.2801 |
|
| 84 |
D |
B |
0.0000 |
|
| 85 |
E |
B |
-1.3562 |
|
| 86 |
A |
B |
0.0000 |
|
| 87 |
D |
B |
-1.2277 |
|
| 88 |
Y |
B |
0.0000 |
|
| 89 |
Y |
B |
0.2996 |
|
| 90 |
C |
B |
0.0000 |
|
| 91 |
Q |
B |
0.0000 |
|
| 92 |
V |
B |
0.0000 |
|
| 93 |
W |
B |
0.8710 |
|
| 94 |
D |
B |
0.0000 |
|
| 95 |
S |
B |
-0.8171 |
|
| 96 |
S |
B |
-0.9564 |
|
| 97 |
S |
B |
-1.0713 |
|
| 98 |
D |
B |
-1.8926 |
|
| 99 |
H |
B |
-0.6654 |
|
| 100 |
V |
B |
1.6305 |
|
| 101 |
V |
B |
1.8384 |
|
| 102 |
F |
B |
2.2394 |
|
| 103 |
G |
B |
0.8392 |
|
| 104 |
G |
B |
-0.0492 |
|
| 105 |
G |
B |
-0.3301 |
|
| 106 |
T |
B |
0.0000 |
|
| 107 |
K |
B |
-0.9315 |
|
| 108 |
L |
B |
0.0000 |
|
| 109 |
T |
B |
0.0000 |
|
| 110 |
V |
B |
0.0000 |
|
| 111 |
L |
B |
-0.4518 |
|
| 112 |
G |
B |
-0.8457 |
|
| 113 |
Q |
B |
-1.1025 |
|
| 114 |
P |
B |
-1.2127 |
|
| 115 |
K |
B |
-2.1086 |
|
| 116 |
A |
B |
-1.2452 |
|
| 117 |
A |
B |
-0.7313 |
|
| 118 |
P |
B |
0.0000 |
|
| 119 |
S |
B |
-0.4737 |
|
| 120 |
V |
B |
0.0000 |
|
| 121 |
T |
B |
0.2300 |
|
| 122 |
L |
B |
0.7446 |
|
| 123 |
F |
B |
1.7887 |
|
| 124 |
P |
B |
0.8929 |
|
| 125 |
P |
B |
0.0000 |
|
| 126 |
S |
B |
-0.8510 |
|
| 127 |
S |
B |
-1.3286 |
|
| 128 |
E |
B |
-2.7312 |
|
| 129 |
E |
B |
-2.3073 |
|
| 130 |
L |
B |
-2.3168 |
|
| 131 |
Q |
B |
-2.5299 |
|
| 132 |
A |
B |
-2.1023 |
|
| 133 |
N |
B |
-2.8367 |
|
| 134 |
K |
B |
-2.8898 |
|
| 135 |
A |
B |
0.0000 |
|
| 136 |
T |
B |
-0.0466 |
|
| 137 |
L |
B |
0.0000 |
|
| 138 |
V |
B |
1.1500 |
|
| 139 |
C |
B |
0.0000 |
|
| 140 |
L |
B |
0.9198 |
|
| 141 |
I |
B |
0.0000 |
|
| 142 |
S |
B |
-0.8167 |
|
| 143 |
D |
B |
-1.9434 |
|
| 144 |
F |
B |
0.0000 |
|
| 145 |
Y |
B |
0.0000 |
|
| 146 |
P |
B |
0.0000 |
|
| 147 |
G |
B |
-0.8127 |
|
| 148 |
A |
B |
-0.1065 |
|
| 149 |
V |
B |
0.1315 |
|
| 150 |
T |
B |
0.0115 |
|
| 151 |
V |
B |
-0.0549 |
|
| 152 |
A |
B |
-0.3791 |
|
| 153 |
W |
B |
0.0000 |
|
| 154 |
K |
B |
-0.8901 |
|
| 155 |
A |
B |
0.0000 |
|
| 156 |
D |
B |
-1.3302 |
|
| 157 |
S |
B |
-0.8594 |
|
| 158 |
S |
B |
-0.7853 |
|
| 159 |
P |
B |
-0.9102 |
|
| 160 |
V |
B |
-0.8460 |
|
| 161 |
K |
B |
-1.7837 |
|
| 162 |
A |
B |
-0.9783 |
|
| 163 |
G |
B |
-0.8037 |
|
| 164 |
V |
B |
-0.6858 |
|
| 165 |
E |
B |
-1.6476 |
|
| 166 |
T |
B |
-0.6681 |
|
| 167 |
T |
B |
-0.4658 |
|
| 168 |
T |
B |
-0.2932 |
|
| 169 |
P |
B |
-0.6651 |
|
| 170 |
S |
B |
-1.5729 |
|
| 171 |
K |
B |
-3.1314 |
|
| 172 |
Q |
B |
-3.0799 |
|
| 173 |
S |
B |
-2.1013 |
|
| 174 |
N |
B |
-2.5766 |
|
| 175 |
N |
B |
-3.0865 |
|
| 176 |
K |
B |
-2.7572 |
|
| 177 |
Y |
B |
-1.8601 |
|
| 178 |
A |
B |
-1.0639 |
|
| 179 |
A |
B |
0.0000 |
|
| 180 |
S |
B |
0.0058 |
|
| 181 |
S |
B |
0.0000 |
|
| 182 |
Y |
B |
0.2339 |
|
| 183 |
L |
B |
0.0000 |
|
| 184 |
S |
B |
-0.6792 |
|
| 185 |
L |
B |
0.0000 |
|
| 186 |
T |
B |
-1.9438 |
|
| 187 |
P |
B |
-2.5628 |
|
| 188 |
E |
B |
-3.1767 |
|
| 189 |
Q |
B |
-2.3451 |
|
| 190 |
W |
B |
0.0000 |
|
| 191 |
K |
B |
-3.0651 |
|
| 192 |
S |
B |
-2.4034 |
|
| 193 |
H |
B |
-2.3384 |
|
| 194 |
R |
B |
-2.6899 |
|
| 195 |
S |
B |
-1.7433 |
|
| 196 |
Y |
B |
0.0000 |
|
| 197 |
S |
B |
-1.0045 |
|
| 198 |
C |
B |
0.0000 |
|
| 199 |
Q |
B |
-1.0565 |
|
| 200 |
V |
B |
0.0000 |
|
| 201 |
T |
B |
-0.4799 |
|
| 202 |
H |
B |
0.0000 |
|
| 203 |
E |
B |
-1.1541 |
|
| 204 |
G |
B |
-0.9201 |
|
| 205 |
S |
B |
-0.6121 |
|
| 206 |
T |
B |
-0.6729 |
|
| 207 |
V |
B |
-0.8955 |
|
| 208 |
E |
B |
-2.1582 |
|
| 209 |
K |
B |
-1.4949 |
|
| 210 |
T |
B |
-0.7894 |
|
| 211 |
V |
B |
0.0000 |
|
| 212 |
A |
B |
-1.3292 |
|
| 213 |
P |
B |
0.0000 |
|
| 214 |
T |
B |
-1.4400 |
|
| 215 |
E |
B |
-1.7003 |
|
| 216 |
C |
B |
-0.2284 |
|