Project name: 6and:L
Status: done
submitted: 2019-03-20 20:40:51, status changed: 2019-03-20 20:54:25
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSSLSASVGDRVTITCRSSQSIVFLEWYQQKPGKAPKLLIYKVSNRFSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCFQGSQFPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.4345
-
Maximal score value
-
1.8439
-
Average score
-
-0.7582
-
Total score value
-
-160.7368
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.8813 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
Q |
L |
-1.9091 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-1.1832 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.5893 |
|
| 8 |
P |
L |
-0.4764 |
|
| 9 |
S |
L |
-0.9074 |
|
| 10 |
S |
L |
-0.9288 |
|
| 11 |
L |
L |
-0.5773 |
|
| 12 |
S |
L |
-0.9146 |
|
| 13 |
A |
L |
0.0000 |
|
| 14 |
S |
L |
-1.0761 |
|
| 15 |
V |
L |
-0.3863 |
|
| 16 |
G |
L |
-0.9184 |
|
| 17 |
D |
L |
-1.9492 |
|
| 18 |
R |
L |
-2.3597 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6036 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.9263 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.7741 |
|
| 25 |
S |
L |
0.0000 |
|
| 26 |
S |
L |
-1.9262 |
|
| 27 |
Q |
L |
-1.7239 |
|
| 28 |
S |
L |
-0.7158 |
|
| 29 |
I |
L |
0.0000 |
|
| 30 |
V |
L |
1.8439 |
|
| 32 |
F |
L |
1.6512 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
E |
L |
0.3778 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.0119 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.5158 |
|
| 39 |
K |
L |
-1.8075 |
|
| 40 |
P |
L |
-1.4095 |
|
| 41 |
G |
L |
-1.4840 |
|
| 42 |
K |
L |
-2.3609 |
|
| 43 |
A |
L |
-1.4312 |
|
| 44 |
P |
L |
-1.3964 |
|
| 45 |
K |
L |
-1.5398 |
|
| 46 |
L |
L |
-0.2671 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
-0.0729 |
|
| 50 |
K |
L |
-0.7919 |
|
| 51 |
V |
L |
-0.4747 |
|
| 52 |
S |
L |
-0.9745 |
|
| 53 |
N |
L |
-1.2024 |
|
| 54 |
R |
L |
-1.0127 |
|
| 55 |
F |
L |
0.1593 |
|
| 56 |
S |
L |
-0.0926 |
|
| 57 |
G |
L |
-0.3869 |
|
| 58 |
V |
L |
-0.3725 |
|
| 59 |
P |
L |
-0.4146 |
|
| 60 |
S |
L |
-0.6754 |
|
| 61 |
R |
L |
-0.9095 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.6426 |
|
| 64 |
G |
L |
0.0000 |
|
| 65 |
S |
L |
-0.8646 |
|
| 66 |
G |
L |
-1.1422 |
|
| 67 |
S |
L |
-0.6720 |
|
| 68 |
G |
L |
-0.5357 |
|
| 69 |
T |
L |
-1.5675 |
|
| 70 |
D |
L |
-2.7467 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.8049 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.5819 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.3449 |
|
| 77 |
S |
L |
-1.2561 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-0.9458 |
|
| 80 |
P |
L |
-1.3670 |
|
| 81 |
E |
L |
-2.0777 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
-0.8832 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
-1.0908 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
-0.0074 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
F |
L |
1.3600 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
G |
L |
1.1620 |
|
| 92 |
S |
L |
1.1505 |
|
| 93 |
Q |
L |
0.3239 |
|
| 94 |
F |
L |
1.5727 |
|
| 95 |
P |
L |
0.9703 |
|
| 96 |
Y |
L |
1.5587 |
|
| 97 |
T |
L |
0.8846 |
|
| 98 |
F |
L |
1.4647 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
Q |
L |
-0.9932 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-2.0008 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-1.4856 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.7314 |
|
| 108 |
R |
L |
-1.1258 |
|
| 109 |
T |
L |
-0.1279 |
|
| 110 |
V |
L |
0.4151 |
|
| 111 |
A |
L |
-0.0694 |
|
| 112 |
A |
L |
-0.1918 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1179 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.3949 |
|
| 117 |
I |
L |
1.2710 |
|
| 118 |
F |
L |
1.5052 |
|
| 119 |
P |
L |
0.0695 |
|
| 120 |
P |
L |
-0.6409 |
|
| 121 |
S |
L |
-1.7830 |
|
| 122 |
D |
L |
-3.3135 |
|
| 123 |
E |
L |
-3.4094 |
|
| 124 |
Q |
L |
-2.3946 |
|
| 125 |
L |
L |
-2.4755 |
|
| 126 |
K |
L |
-3.0469 |
|
| 127 |
S |
L |
-1.9211 |
|
| 128 |
G |
L |
-1.4957 |
|
| 129 |
T |
L |
-1.3257 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0578 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7655 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.5581 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.5513 |
|
| 138 |
N |
L |
-1.3390 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.8139 |
|
| 142 |
R |
L |
-3.0127 |
|
| 143 |
E |
L |
-3.2343 |
|
| 144 |
A |
L |
-2.3269 |
|
| 145 |
K |
L |
-2.4591 |
|
| 146 |
V |
L |
-1.1814 |
|
| 147 |
Q |
L |
-0.7038 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.6020 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.7298 |
|
| 152 |
N |
L |
-1.4859 |
|
| 153 |
A |
L |
-0.2621 |
|
| 154 |
L |
L |
0.6454 |
|
| 155 |
Q |
L |
-0.3597 |
|
| 156 |
S |
L |
-0.7108 |
|
| 157 |
G |
L |
-1.4347 |
|
| 158 |
N |
L |
-1.8484 |
|
| 159 |
S |
L |
-1.8523 |
|
| 160 |
Q |
L |
-2.4719 |
|
| 161 |
E |
L |
-2.3335 |
|
| 162 |
S |
L |
-1.3308 |
|
| 163 |
V |
L |
-0.8155 |
|
| 164 |
T |
L |
-1.1849 |
|
| 165 |
E |
L |
-2.1791 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.0209 |
|
| 168 |
S |
L |
-2.1290 |
|
| 169 |
K |
L |
-2.6083 |
|
| 170 |
D |
L |
-2.1204 |
|
| 171 |
S |
L |
-2.0370 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.9522 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.4756 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.7306 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.7646 |
|
| 181 |
L |
L |
-0.8644 |
|
| 182 |
S |
L |
-1.0516 |
|
| 183 |
K |
L |
-2.0507 |
|
| 184 |
A |
L |
-1.8320 |
|
| 185 |
D |
L |
-2.5242 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.2105 |
|
| 188 |
K |
L |
-3.4345 |
|
| 189 |
H |
L |
-2.8171 |
|
| 190 |
K |
L |
-2.6281 |
|
| 191 |
V |
L |
-1.0569 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.7412 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.2015 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.7905 |
|
| 200 |
G |
L |
-0.4221 |
|
| 201 |
L |
L |
-0.2367 |
|
| 202 |
S |
L |
-0.4612 |
|
| 203 |
S |
L |
-0.4138 |
|
| 204 |
P |
L |
-0.6208 |
|
| 205 |
V |
L |
0.0476 |
|
| 206 |
T |
L |
-0.3739 |
|
| 207 |
K |
L |
-0.2705 |
|
| 208 |
S |
L |
-0.1990 |
|
| 209 |
F |
L |
-0.6126 |
|
| 210 |
N |
L |
-1.7045 |
|
| 211 |
R |
L |
-2.2420 |
|
| 212 |
G |
L |
-2.1722 |
|
| 213 |
E |
L |
-2.4388 |
|