Project name: 2xa8:L
Status: done
submitted: 2019-03-20 20:06:51, status changed: 2019-03-20 20:18:13
Settings
|
Chain sequence(s)
|
L: DIQLTQSPSSLSASVGDRVTITCRASQSVDYDGDSYMNWYQQKPGKAPKLLIYAASYLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSHEDPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6736
-
Maximal score value
-
1.5925
-
Average score
-
-0.8449
-
Total score value
-
-184.1856
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-2.7286 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
Q |
L |
-2.1125 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
T |
L |
-1.1840 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.8583 |
|
| 8 |
P |
L |
-0.4576 |
|
| 9 |
S |
L |
-0.7813 |
|
| 10 |
S |
L |
-0.5946 |
|
| 11 |
L |
L |
-0.4593 |
|
| 12 |
S |
L |
-0.7084 |
|
| 13 |
A |
L |
-1.2847 |
|
| 14 |
S |
L |
-1.3638 |
|
| 15 |
V |
L |
-0.5396 |
|
| 16 |
G |
L |
-1.2119 |
|
| 17 |
D |
L |
-2.6604 |
|
| 18 |
R |
L |
-2.7627 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.5589 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.8729 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.7437 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-2.0521 |
|
| 27 |
Q |
L |
-2.3460 |
|
| 28 |
S |
L |
-1.2381 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
D |
L |
-1.0756 |
|
| 31 |
Y |
L |
-0.3036 |
|
| 32 |
D |
L |
-1.7340 |
|
| 33 |
G |
L |
-1.3847 |
|
| 34 |
D |
L |
-1.1309 |
|
| 35 |
S |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.1065 |
|
| 37 |
M |
L |
0.0000 |
|
| 38 |
N |
L |
0.0000 |
|
| 39 |
W |
L |
0.0000 |
|
| 40 |
Y |
L |
0.1307 |
|
| 41 |
Q |
L |
0.0000 |
|
| 42 |
Q |
L |
-1.3106 |
|
| 43 |
K |
L |
-1.7933 |
|
| 44 |
P |
L |
-1.4947 |
|
| 45 |
G |
L |
-1.4989 |
|
| 46 |
K |
L |
-2.3495 |
|
| 47 |
A |
L |
-1.3365 |
|
| 48 |
P |
L |
-1.1957 |
|
| 49 |
K |
L |
-1.3208 |
|
| 50 |
L |
L |
-0.0422 |
|
| 51 |
L |
L |
0.0000 |
|
| 52 |
I |
L |
0.0000 |
|
| 53 |
Y |
L |
1.2187 |
|
| 54 |
A |
L |
0.4288 |
|
| 55 |
A |
L |
0.0000 |
|
| 56 |
S |
L |
0.4665 |
|
| 57 |
Y |
L |
1.5309 |
|
| 58 |
L |
L |
0.9804 |
|
| 59 |
E |
L |
0.0445 |
|
| 60 |
S |
L |
-0.2840 |
|
| 61 |
G |
L |
-0.5341 |
|
| 62 |
V |
L |
-0.3789 |
|
| 63 |
P |
L |
-0.4505 |
|
| 64 |
S |
L |
-0.4989 |
|
| 65 |
R |
L |
-0.8159 |
|
| 66 |
F |
L |
0.0000 |
|
| 67 |
S |
L |
-0.0882 |
|
| 68 |
G |
L |
0.0739 |
|
| 69 |
S |
L |
-0.5215 |
|
| 70 |
G |
L |
-1.1104 |
|
| 71 |
S |
L |
-1.2705 |
|
| 72 |
G |
L |
-1.2333 |
|
| 73 |
T |
L |
-1.8048 |
|
| 74 |
D |
L |
-2.1826 |
|
| 75 |
F |
L |
0.0000 |
|
| 76 |
T |
L |
-0.8095 |
|
| 77 |
L |
L |
0.0000 |
|
| 78 |
T |
L |
-0.6123 |
|
| 79 |
I |
L |
0.0000 |
|
| 80 |
S |
L |
-1.4939 |
|
| 81 |
S |
L |
-1.5376 |
|
| 82 |
L |
L |
0.0000 |
|
| 83 |
Q |
L |
-1.3176 |
|
| 84 |
P |
L |
-1.6863 |
|
| 85 |
E |
L |
-2.2958 |
|
| 86 |
D |
L |
0.0000 |
|
| 87 |
F |
L |
-1.0399 |
|
| 88 |
A |
L |
0.0000 |
|
| 89 |
T |
L |
-0.5912 |
|
| 90 |
Y |
L |
0.0000 |
|
| 91 |
Y |
L |
0.0581 |
|
| 92 |
C |
L |
0.0000 |
|
| 93 |
Q |
L |
0.0000 |
|
| 94 |
Q |
L |
0.0000 |
|
| 95 |
S |
L |
-0.4270 |
|
| 96 |
H |
L |
-1.2889 |
|
| 97 |
E |
L |
-2.6730 |
|
| 98 |
D |
L |
-2.5349 |
|
| 99 |
P |
L |
-1.2142 |
|
| 100 |
Y |
L |
-0.2355 |
|
| 101 |
T |
L |
-0.1665 |
|
| 102 |
F |
L |
0.9102 |
|
| 103 |
G |
L |
-0.5610 |
|
| 104 |
Q |
L |
-1.1661 |
|
| 105 |
G |
L |
0.0000 |
|
| 106 |
T |
L |
0.0000 |
|
| 107 |
K |
L |
-0.8851 |
|
| 108 |
V |
L |
0.0000 |
|
| 109 |
E |
L |
-1.0742 |
|
| 110 |
I |
L |
0.0000 |
|
| 111 |
K |
L |
-1.8526 |
|
| 112 |
R |
L |
-1.0437 |
|
| 113 |
T |
L |
-0.2661 |
|
| 114 |
V |
L |
0.0544 |
|
| 115 |
A |
L |
-0.0317 |
|
| 116 |
A |
L |
-0.2472 |
|
| 117 |
P |
L |
0.0000 |
|
| 118 |
S |
L |
-0.1284 |
|
| 119 |
V |
L |
0.0000 |
|
| 120 |
F |
L |
1.0494 |
|
| 121 |
I |
L |
1.1531 |
|
| 122 |
F |
L |
1.5925 |
|
| 123 |
P |
L |
0.2282 |
|
| 124 |
P |
L |
0.0000 |
|
| 125 |
S |
L |
-1.6320 |
|
| 126 |
D |
L |
-3.1288 |
|
| 127 |
E |
L |
-3.3800 |
|
| 128 |
Q |
L |
-2.4627 |
|
| 129 |
L |
L |
-2.5845 |
|
| 130 |
K |
L |
-3.0488 |
|
| 131 |
S |
L |
-1.9841 |
|
| 132 |
G |
L |
-1.4782 |
|
| 133 |
T |
L |
-1.4123 |
|
| 134 |
A |
L |
0.0000 |
|
| 135 |
S |
L |
0.0688 |
|
| 136 |
V |
L |
0.0000 |
|
| 137 |
V |
L |
0.7120 |
|
| 138 |
C |
L |
0.0000 |
|
| 139 |
L |
L |
0.4704 |
|
| 140 |
L |
L |
0.0000 |
|
| 141 |
N |
L |
-0.5639 |
|
| 142 |
N |
L |
-1.1756 |
|
| 143 |
F |
L |
0.0000 |
|
| 144 |
Y |
L |
0.0000 |
|
| 145 |
P |
L |
-1.8923 |
|
| 146 |
R |
L |
-2.8415 |
|
| 147 |
E |
L |
-3.1481 |
|
| 148 |
A |
L |
-2.2740 |
|
| 149 |
K |
L |
-2.2900 |
|
| 150 |
V |
L |
-1.1405 |
|
| 151 |
Q |
L |
-0.8114 |
|
| 152 |
W |
L |
0.0000 |
|
| 153 |
K |
L |
-0.8142 |
|
| 154 |
V |
L |
0.0000 |
|
| 155 |
D |
L |
-2.0188 |
|
| 156 |
N |
L |
-1.6688 |
|
| 157 |
A |
L |
-0.5564 |
|
| 158 |
L |
L |
0.0193 |
|
| 159 |
Q |
L |
-0.4385 |
|
| 160 |
S |
L |
-0.6877 |
|
| 161 |
G |
L |
-1.0194 |
|
| 162 |
N |
L |
-0.9101 |
|
| 163 |
S |
L |
-1.4800 |
|
| 164 |
Q |
L |
-2.3399 |
|
| 165 |
E |
L |
-2.3466 |
|
| 166 |
S |
L |
-1.3520 |
|
| 167 |
V |
L |
-0.9591 |
|
| 168 |
T |
L |
-1.1288 |
|
| 169 |
E |
L |
-2.0808 |
|
| 170 |
Q |
L |
0.0000 |
|
| 171 |
D |
L |
-1.9965 |
|
| 172 |
S |
L |
-2.2312 |
|
| 173 |
K |
L |
-2.5500 |
|
| 174 |
D |
L |
-2.1031 |
|
| 175 |
S |
L |
0.0000 |
|
| 176 |
T |
L |
0.0000 |
|
| 177 |
Y |
L |
0.0000 |
|
| 178 |
S |
L |
-0.8967 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
S |
L |
-0.5470 |
|
| 181 |
S |
L |
0.0000 |
|
| 182 |
T |
L |
-0.6135 |
|
| 183 |
L |
L |
0.0000 |
|
| 184 |
T |
L |
-0.5159 |
|
| 185 |
L |
L |
-0.7143 |
|
| 186 |
S |
L |
-1.3224 |
|
| 187 |
K |
L |
-2.2471 |
|
| 188 |
A |
L |
-2.0016 |
|
| 189 |
D |
L |
-2.6835 |
|
| 190 |
Y |
L |
0.0000 |
|
| 191 |
E |
L |
-3.4778 |
|
| 192 |
K |
L |
-3.6736 |
|
| 193 |
H |
L |
-3.0481 |
|
| 194 |
K |
L |
-3.1727 |
|
| 195 |
V |
L |
-1.4882 |
|
| 196 |
Y |
L |
0.0000 |
|
| 197 |
A |
L |
0.0000 |
|
| 198 |
C |
L |
0.0000 |
|
| 199 |
E |
L |
-0.8585 |
|
| 200 |
V |
L |
0.0000 |
|
| 201 |
T |
L |
-1.2299 |
|
| 202 |
H |
L |
0.0000 |
|
| 203 |
Q |
L |
-1.7763 |
|
| 204 |
G |
L |
-0.4642 |
|
| 205 |
L |
L |
-0.2068 |
|
| 206 |
S |
L |
-0.4307 |
|
| 207 |
S |
L |
-0.4126 |
|
| 208 |
P |
L |
-0.5669 |
|
| 209 |
V |
L |
-0.0508 |
|
| 210 |
T |
L |
-0.4956 |
|
| 211 |
K |
L |
-0.5579 |
|
| 212 |
S |
L |
-0.3583 |
|
| 213 |
F |
L |
-0.7113 |
|
| 214 |
N |
L |
-1.7821 |
|
| 215 |
R |
L |
-2.3268 |
|
| 216 |
G |
L |
-1.8922 |
|
| 217 |
E |
L |
-2.1513 |
|
| 218 |
C |
L |
-0.8205 |
|