Project name: 4hjg:A
Status: done
submitted: 2019-03-20 20:17:50, status changed: 2019-03-20 20:28:22
Settings
|
Chain sequence(s)
|
A: DIQMTQSPIILLSSASVGDDRRVTITCRASQDVNTAVAWYQQRTNGSPRLLIYSASFLYSSGVPSRFSGSRSGTDFTTLTISSLQPEDIADYYCQQHYTTPPTFGAGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKKVDNALQSGNSQESVTEEQDSKDSTYSLSSTLTLSKADYEKHKVVYACEVTHQGLSSPVTKSFNRGEC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.5971
-
Maximal score value
-
2.5097
-
Average score
-
-0.6552
-
Total score value
-
-140.2109
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-2.2835 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
Q |
A |
-1.7813 |
|
| 4 |
M |
A |
0.0000 |
|
| 5 |
T |
A |
-0.9259 |
|
| 6 |
Q |
A |
0.0000 |
|
| 7 |
S |
A |
0.2793 |
|
| 8 |
P |
A |
1.0224 |
|
| 9 |
I |
A |
2.1878 |
|
| 10 |
L |
A |
1.5636 |
|
| 11 |
L |
A |
0.6820 |
|
| 12 |
S |
A |
-0.3423 |
|
| 13 |
A |
A |
-0.9928 |
|
| 14 |
S |
A |
-0.9034 |
|
| 15 |
V |
A |
-0.0741 |
|
| 16 |
G |
A |
-1.0428 |
|
| 17 |
D |
A |
-2.4625 |
|
| 18 |
R |
A |
-2.6813 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
T |
A |
-0.5349 |
|
| 21 |
I |
A |
0.0000 |
|
| 22 |
T |
A |
-0.5566 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.8261 |
|
| 25 |
A |
A |
0.0000 |
|
| 26 |
S |
A |
-2.1627 |
|
| 27 |
Q |
A |
-2.7150 |
|
| 28 |
D |
A |
-2.6455 |
|
| 29 |
V |
A |
0.0000 |
|
| 30 |
N |
A |
-1.9579 |
|
| 31 |
T |
A |
-1.0079 |
|
| 32 |
A |
A |
-0.4928 |
|
| 33 |
V |
A |
0.0000 |
|
| 34 |
A |
A |
0.8154 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
0.0182 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-1.6687 |
|
| 39 |
R |
A |
-2.4191 |
|
| 40 |
T |
A |
-1.7542 |
|
| 41 |
N |
A |
-1.9068 |
|
| 42 |
G |
A |
-1.6011 |
|
| 43 |
S |
A |
-1.1305 |
|
| 44 |
P |
A |
-1.1014 |
|
| 45 |
R |
A |
-0.7731 |
|
| 46 |
L |
A |
0.4212 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
Y |
A |
1.6550 |
|
| 50 |
S |
A |
0.3713 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
0.9242 |
|
| 53 |
F |
A |
2.5097 |
|
| 54 |
L |
A |
1.9364 |
|
| 55 |
Y |
A |
1.6635 |
|
| 56 |
S |
A |
0.4379 |
|
| 57 |
G |
A |
-0.2762 |
|
| 58 |
V |
A |
0.0000 |
|
| 59 |
P |
A |
-0.2584 |
|
| 60 |
S |
A |
-0.3422 |
|
| 61 |
R |
A |
-0.7597 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
0.0328 |
|
| 64 |
G |
A |
0.1121 |
|
| 65 |
S |
A |
-0.5709 |
|
| 66 |
R |
A |
-1.6292 |
|
| 67 |
S |
A |
-1.3749 |
|
| 68 |
G |
A |
-1.8369 |
|
| 69 |
T |
A |
-2.2549 |
|
| 70 |
D |
A |
-2.1003 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.7961 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
T |
A |
-0.6320 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
S |
A |
-1.5909 |
|
| 77 |
S |
A |
-1.3603 |
|
| 78 |
L |
A |
0.0000 |
|
| 79 |
Q |
A |
-0.8863 |
|
| 80 |
P |
A |
-1.4178 |
|
| 81 |
E |
A |
-1.8713 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
I |
A |
0.0000 |
|
| 84 |
A |
A |
0.0000 |
|
| 85 |
D |
A |
-0.9033 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
0.3333 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.5329 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
H |
A |
-0.5521 |
|
| 92 |
Y |
A |
-0.1150 |
|
| 93 |
T |
A |
-0.2945 |
|
| 94 |
T |
A |
-0.6037 |
|
| 95 |
P |
A |
-0.6801 |
|
| 96 |
P |
A |
-0.4721 |
|
| 97 |
T |
A |
0.0670 |
|
| 98 |
F |
A |
1.4014 |
|
| 99 |
G |
A |
0.0000 |
|
| 100 |
A |
A |
0.5561 |
|
| 101 |
G |
A |
0.5543 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
0.0299 |
|
| 104 |
V |
A |
0.0000 |
|
| 105 |
E |
A |
0.0000 |
|
| 106 |
I |
A |
0.0000 |
|
| 107 |
K |
A |
-0.8768 |
|
| 108 |
R |
A |
-0.6730 |
|
| 109 |
T |
A |
-0.0713 |
|
| 110 |
V |
A |
0.3925 |
|
| 111 |
A |
A |
-0.0828 |
|
| 112 |
A |
A |
-0.2706 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
-0.0382 |
|
| 115 |
V |
A |
0.0000 |
|
| 116 |
F |
A |
1.5948 |
|
| 117 |
I |
A |
1.4132 |
|
| 118 |
F |
A |
1.5445 |
|
| 119 |
P |
A |
-0.1871 |
|
| 120 |
P |
A |
0.0000 |
|
| 121 |
S |
A |
-1.7950 |
|
| 122 |
D |
A |
-3.2390 |
|
| 123 |
E |
A |
-3.4303 |
|
| 124 |
Q |
A |
-2.5058 |
|
| 125 |
L |
A |
-2.6198 |
|
| 126 |
K |
A |
-3.1061 |
|
| 127 |
S |
A |
-1.9899 |
|
| 128 |
G |
A |
-1.3456 |
|
| 129 |
T |
A |
-0.9993 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
0.0575 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.8350 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.6069 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.5703 |
|
| 138 |
N |
A |
-1.3595 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
0.0000 |
|
| 141 |
P |
A |
-1.2193 |
|
| 142 |
R |
A |
-1.7660 |
|
| 143 |
E |
A |
-2.6776 |
|
| 144 |
A |
A |
-2.1177 |
|
| 145 |
K |
A |
-2.3896 |
|
| 146 |
V |
A |
0.0000 |
|
| 147 |
Q |
A |
-0.8647 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.7445 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-1.9896 |
|
| 152 |
N |
A |
-1.5872 |
|
| 153 |
A |
A |
-0.3096 |
|
| 154 |
L |
A |
0.6859 |
|
| 155 |
Q |
A |
-0.1353 |
|
| 156 |
S |
A |
-0.4236 |
|
| 157 |
G |
A |
-0.9847 |
|
| 158 |
N |
A |
-0.9283 |
|
| 159 |
S |
A |
-1.3803 |
|
| 160 |
Q |
A |
-2.1734 |
|
| 161 |
E |
A |
-2.0207 |
|
| 162 |
S |
A |
-0.8725 |
|
| 163 |
V |
A |
0.1762 |
|
| 164 |
T |
A |
-0.3336 |
|
| 165 |
E |
A |
-1.0586 |
|
| 166 |
Q |
A |
0.0000 |
|
| 167 |
D |
A |
-2.1957 |
|
| 168 |
S |
A |
-2.3216 |
|
| 169 |
K |
A |
-2.7415 |
|
| 170 |
D |
A |
-2.2374 |
|
| 171 |
S |
A |
0.0000 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
0.0000 |
|
| 174 |
S |
A |
-0.5599 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.2598 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.5379 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.4741 |
|
| 181 |
L |
A |
-0.6610 |
|
| 182 |
S |
A |
-1.2656 |
|
| 183 |
K |
A |
-2.1635 |
|
| 184 |
A |
A |
-1.9032 |
|
| 185 |
D |
A |
-2.5279 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.4899 |
|
| 188 |
K |
A |
-3.5971 |
|
| 189 |
H |
A |
-2.9405 |
|
| 190 |
K |
A |
-3.3668 |
|
| 191 |
V |
A |
-1.6979 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
0.0000 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-1.0918 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.2706 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.6615 |
|
| 200 |
G |
A |
-0.4980 |
|
| 201 |
L |
A |
-0.2464 |
|
| 202 |
S |
A |
-0.4559 |
|
| 203 |
S |
A |
-0.4393 |
|
| 204 |
P |
A |
-0.5705 |
|
| 205 |
V |
A |
-0.0884 |
|
| 206 |
T |
A |
-0.4744 |
|
| 207 |
K |
A |
-0.4366 |
|
| 208 |
S |
A |
-0.4329 |
|
| 209 |
F |
A |
0.0000 |
|
| 210 |
N |
A |
-2.1231 |
|
| 211 |
R |
A |
-2.6533 |
|
| 212 |
G |
A |
-2.0822 |
|
| 213 |
E |
A |
-2.2609 |
|
| 214 |
C |
A |
-0.4375 |
|