Project name: 5nhw:L
Status: done
submitted: 2019-03-21 13:06:39, status changed: 2019-03-21 13:18:15
Settings
|
Chain sequence(s)
|
L: SALTQPASVSGSPGQSITISCTGTSSDVGSYNYVNWYQQHPGKAPKLMIYGVSKRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCGTFAGGSYYGVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTEA
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.1844
-
Maximal score value
-
1.8546
-
Average score
-
-0.6954
-
Total score value
-
-149.5097
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 2 |
S |
L |
0.1207 |
|
| 3 |
A |
L |
0.2446 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
T |
L |
-0.0684 |
|
| 6 |
Q |
L |
-0.2066 |
|
| 7 |
P |
L |
-0.3302 |
|
| 8 |
A |
L |
-0.5172 |
|
| 9 |
S |
L |
-0.6188 |
|
| 10 |
V |
L |
-0.3013 |
|
| 11 |
S |
L |
-0.6885 |
|
| 12 |
G |
L |
0.0000 |
|
| 13 |
S |
L |
-0.8738 |
|
| 14 |
P |
L |
-1.1991 |
|
| 15 |
G |
L |
-1.4566 |
|
| 16 |
Q |
L |
-1.7594 |
|
| 17 |
S |
L |
-1.0113 |
|
| 18 |
I |
L |
-0.2796 |
|
| 19 |
T |
L |
-0.0412 |
|
| 20 |
I |
L |
0.0000 |
|
| 21 |
S |
L |
-0.2262 |
|
| 22 |
C |
L |
0.0000 |
|
| 23 |
T |
L |
-0.4766 |
|
| 24 |
G |
L |
-0.4929 |
|
| 25 |
T |
L |
-0.6070 |
|
| 26 |
S |
L |
-0.6851 |
|
| 27 |
S |
L |
-0.4733 |
|
| 28 |
D |
L |
0.0000 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
G |
L |
-1.0243 |
|
| 31 |
S |
L |
-0.5652 |
|
| 32 |
Y |
L |
-0.1273 |
|
| 33 |
N |
L |
-1.0099 |
|
| 34 |
Y |
L |
0.0000 |
|
| 35 |
V |
L |
0.0000 |
|
| 36 |
N |
L |
0.0000 |
|
| 37 |
W |
L |
0.0000 |
|
| 38 |
Y |
L |
0.0506 |
|
| 39 |
Q |
L |
0.0000 |
|
| 40 |
Q |
L |
-1.5237 |
|
| 41 |
H |
L |
-1.8073 |
|
| 42 |
P |
L |
-1.3394 |
|
| 43 |
G |
L |
-1.5078 |
|
| 44 |
K |
L |
-2.3392 |
|
| 45 |
A |
L |
-1.4188 |
|
| 46 |
P |
L |
-1.3376 |
|
| 47 |
K |
L |
-1.4483 |
|
| 48 |
L |
L |
-0.2305 |
|
| 49 |
M |
L |
0.0000 |
|
| 50 |
I |
L |
0.0000 |
|
| 51 |
Y |
L |
-0.5425 |
|
| 52 |
G |
L |
-0.8254 |
|
| 53 |
V |
L |
0.0000 |
|
| 54 |
S |
L |
-1.6170 |
|
| 55 |
K |
L |
-2.3032 |
|
| 56 |
R |
L |
-2.1194 |
|
| 57 |
P |
L |
-0.9678 |
|
| 58 |
S |
L |
-0.8630 |
|
| 59 |
G |
L |
-0.8457 |
|
| 60 |
V |
L |
-1.0589 |
|
| 61 |
S |
L |
-1.0867 |
|
| 62 |
N |
L |
-1.7435 |
|
| 63 |
R |
L |
-1.2210 |
|
| 64 |
F |
L |
0.0000 |
|
| 65 |
S |
L |
-1.1533 |
|
| 66 |
G |
L |
-0.9012 |
|
| 67 |
S |
L |
-0.9812 |
|
| 68 |
K |
L |
-1.1569 |
|
| 69 |
S |
L |
-0.8780 |
|
| 70 |
G |
L |
-1.0762 |
|
| 71 |
N |
L |
-1.0446 |
|
| 72 |
T |
L |
-0.7763 |
|
| 73 |
A |
L |
0.0000 |
|
| 74 |
S |
L |
-0.4082 |
|
| 75 |
L |
L |
0.0000 |
|
| 76 |
T |
L |
-0.2434 |
|
| 77 |
I |
L |
0.0000 |
|
| 78 |
S |
L |
-1.1188 |
|
| 79 |
G |
L |
-1.1912 |
|
| 80 |
L |
L |
0.0000 |
|
| 81 |
Q |
L |
-1.8097 |
|
| 82 |
A |
L |
-1.5517 |
|
| 83 |
E |
L |
-2.3107 |
|
| 84 |
D |
L |
0.0000 |
|
| 85 |
E |
L |
-1.8699 |
|
| 86 |
A |
L |
0.0000 |
|
| 87 |
D |
L |
-1.0049 |
|
| 88 |
Y |
L |
0.0000 |
|
| 89 |
Y |
L |
0.2088 |
|
| 90 |
C |
L |
0.0000 |
|
| 91 |
G |
L |
0.0000 |
|
| 92 |
T |
L |
0.0000 |
|
| 93 |
F |
L |
1.6067 |
|
| 94 |
A |
L |
0.9021 |
|
| 95 |
G |
L |
0.0545 |
|
| 96 |
G |
L |
-0.2060 |
|
| 97 |
S |
L |
0.1562 |
|
| 98 |
Y |
L |
1.1301 |
|
| 99 |
Y |
L |
1.5037 |
|
| 100 |
G |
L |
1.1869 |
|
| 101 |
V |
L |
1.5079 |
|
| 102 |
F |
L |
1.8546 |
|
| 103 |
G |
L |
0.0000 |
|
| 104 |
G |
L |
-0.0304 |
|
| 105 |
G |
L |
-0.2431 |
|
| 106 |
T |
L |
0.0000 |
|
| 107 |
K |
L |
-1.1056 |
|
| 108 |
L |
L |
0.0000 |
|
| 109 |
T |
L |
0.0000 |
|
| 110 |
V |
L |
0.0000 |
|
| 111 |
L |
L |
-0.7588 |
|
| 112 |
G |
L |
-0.9800 |
|
| 113 |
Q |
L |
-1.2658 |
|
| 114 |
P |
L |
-1.3540 |
|
| 115 |
K |
L |
-2.2882 |
|
| 116 |
A |
L |
-1.3470 |
|
| 117 |
A |
L |
-0.8056 |
|
| 118 |
P |
L |
-0.3112 |
|
| 119 |
S |
L |
-0.1496 |
|
| 120 |
V |
L |
0.0475 |
|
| 121 |
T |
L |
0.5709 |
|
| 122 |
L |
L |
0.9240 |
|
| 123 |
F |
L |
1.7222 |
|
| 124 |
P |
L |
0.6899 |
|
| 125 |
P |
L |
0.0000 |
|
| 126 |
S |
L |
-1.0451 |
|
| 127 |
S |
L |
-1.6728 |
|
| 128 |
E |
L |
-2.8764 |
|
| 129 |
E |
L |
-2.5204 |
|
| 130 |
L |
L |
-2.4491 |
|
| 131 |
Q |
L |
-2.6577 |
|
| 132 |
A |
L |
-2.2395 |
|
| 133 |
N |
L |
-2.9475 |
|
| 134 |
K |
L |
-3.0925 |
|
| 135 |
A |
L |
0.0000 |
|
| 136 |
T |
L |
-0.0993 |
|
| 137 |
L |
L |
0.0000 |
|
| 138 |
V |
L |
1.1489 |
|
| 139 |
C |
L |
0.0000 |
|
| 140 |
L |
L |
1.0567 |
|
| 141 |
I |
L |
0.0000 |
|
| 142 |
S |
L |
-0.5487 |
|
| 143 |
D |
L |
-1.5745 |
|
| 144 |
F |
L |
0.0000 |
|
| 145 |
Y |
L |
0.0000 |
|
| 146 |
P |
L |
0.0000 |
|
| 147 |
G |
L |
-1.0523 |
|
| 148 |
A |
L |
-0.3322 |
|
| 149 |
V |
L |
-0.0822 |
|
| 150 |
T |
L |
-0.1076 |
|
| 151 |
V |
L |
0.2186 |
|
| 152 |
A |
L |
-0.3412 |
|
| 153 |
W |
L |
0.0000 |
|
| 154 |
K |
L |
-0.8292 |
|
| 155 |
A |
L |
0.0000 |
|
| 156 |
D |
L |
-1.1084 |
|
| 157 |
S |
L |
-0.7585 |
|
| 158 |
S |
L |
-0.4837 |
|
| 159 |
P |
L |
-0.7457 |
|
| 160 |
V |
L |
-0.7797 |
|
| 161 |
K |
L |
-1.8162 |
|
| 162 |
A |
L |
-1.0278 |
|
| 163 |
G |
L |
-0.9175 |
|
| 164 |
V |
L |
-0.9681 |
|
| 165 |
E |
L |
-1.8094 |
|
| 166 |
T |
L |
-0.7035 |
|
| 167 |
T |
L |
-0.4615 |
|
| 168 |
T |
L |
-0.1276 |
|
| 169 |
P |
L |
-0.5497 |
|
| 170 |
S |
L |
-1.2670 |
|
| 171 |
K |
L |
-2.5631 |
|
| 172 |
Q |
L |
-2.0638 |
|
| 173 |
S |
L |
-1.6338 |
|
| 174 |
N |
L |
-2.3248 |
|
| 175 |
N |
L |
-2.4577 |
|
| 176 |
K |
L |
-2.2355 |
|
| 177 |
Y |
L |
-1.4463 |
|
| 178 |
A |
L |
-0.7025 |
|
| 179 |
A |
L |
0.0000 |
|
| 180 |
S |
L |
0.1171 |
|
| 181 |
S |
L |
0.0000 |
|
| 182 |
Y |
L |
0.2969 |
|
| 183 |
L |
L |
0.0000 |
|
| 184 |
S |
L |
-0.6707 |
|
| 185 |
L |
L |
-1.1061 |
|
| 186 |
T |
L |
-1.8791 |
|
| 187 |
P |
L |
-2.5741 |
|
| 188 |
E |
L |
-3.1844 |
|
| 189 |
Q |
L |
-2.3162 |
|
| 190 |
W |
L |
0.0000 |
|
| 191 |
K |
L |
-3.0597 |
|
| 192 |
S |
L |
-2.3900 |
|
| 193 |
H |
L |
-2.3155 |
|
| 194 |
R |
L |
-2.4189 |
|
| 195 |
S |
L |
-1.4139 |
|
| 196 |
Y |
L |
0.0000 |
|
| 197 |
S |
L |
0.0000 |
|
| 198 |
C |
L |
0.0000 |
|
| 199 |
Q |
L |
-0.5194 |
|
| 200 |
V |
L |
0.0000 |
|
| 201 |
T |
L |
-0.5198 |
|
| 202 |
H |
L |
0.0000 |
|
| 203 |
E |
L |
-2.2652 |
|
| 204 |
G |
L |
-1.4436 |
|
| 205 |
S |
L |
-0.8141 |
|
| 206 |
T |
L |
-0.4057 |
|
| 207 |
V |
L |
0.0805 |
|
| 208 |
E |
L |
-0.9466 |
|
| 209 |
K |
L |
-0.6573 |
|
| 210 |
T |
L |
-0.2897 |
|
| 211 |
V |
L |
0.0609 |
|
| 212 |
A |
L |
-1.1403 |
|
| 213 |
P |
L |
-1.3544 |
|
| 214 |
T |
L |
-1.4974 |
|
| 215 |
E |
L |
-1.8242 |
|
| 216 |
A |
L |
-1.0369 |
|