Project name: mab1

Chain sequence(s)	H: QVQLVQSGAEVKKPGSSVKVSCKASGGTFSTYGISWVRQAPGQGLEWMGGIIPIFDTGNSAQSFQGRVTITADESTSTAYMELSSLRSEDTAVYYCARSSRIYDLNPSLTAYYDMDVWGQGTMVTVS; L: SVLTQPPSVSAAPGQKVTISCSGSSSNIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAWVFGGGTKLTVLRT
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.7808
• Maximal score value: 1.8507
• Average score: -0.5838
• Total score value: -138.949

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.1416
2	V	H	-0.3467
3	Q	H	-1.1045
4	L	H	0.0000
5	V	H	-0.4152
6	Q	H	0.0000
7	S	H	-0.7774
8	G	H	-0.6756
9	A	H	-0.0293
10	E	H	-0.2559
11	V	H	0.8251
12	K	H	-0.9309
13	K	H	-2.0700
14	P	H	-1.9698
15	G	H	-1.5438
16	S	H	-1.2372
17	S	H	-1.4133
18	V	H	0.0000
19	K	H	-2.1148
20	V	H	0.0000
21	S	H	-0.7467
22	C	H	0.0000
23	K	H	-1.6585
24	A	H	0.0000
25	S	H	-1.0928
26	G	H	-1.1885
27	G	H	-1.1944
28	T	H	-1.0914
29	F	H	0.0000
30	S	H	-0.1233
31	T	H	1.0347
32	Y	H	0.7853
33	G	H	0.0000
34	I	H	0.0000
35	S	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.5632
40	A	H	-1.0159
41	P	H	-1.0880
42	G	H	-1.2220
43	Q	H	-1.7695
44	G	H	-1.0174
45	L	H	0.0000
46	E	H	-0.5878
47	W	H	-0.1823
48	M	H	0.0000
49	G	H	0.0000
50	G	H	-0.5830
51	I	H	0.0000
52	I	H	0.0000
52A	P	H	0.0000
53	I	H	0.5849
54	F	H	0.7478
55	D	H	-1.4256
56	T	H	-0.8840
57	G	H	-1.4056
58	N	H	-1.8816
59	S	H	-1.6069
60	A	H	-1.2146
61	Q	H	-1.8170
62	S	H	-1.2375
63	F	H	0.0000
64	Q	H	-2.2254
65	G	H	-1.5103
66	R	H	-1.3315
67	V	H	0.0000
68	T	H	-1.0125
69	I	H	-0.6548
70	T	H	-0.7556
71	A	H	-1.2554
72	D	H	-2.0463
73	E	H	-2.2375
74	S	H	-1.3446
75	T	H	-1.3519
76	S	H	0.0000
77	T	H	0.0000
78	A	H	0.0000
79	Y	H	-0.6189
80	M	H	0.0000
81	E	H	-1.5971
82	L	H	0.0000
82A	S	H	-1.1748
82B	S	H	-1.1567
82C	L	H	0.0000
83	R	H	-2.7808
84	S	H	-2.2483
85	E	H	-2.4996
86	D	H	0.0000
87	T	H	-0.6971
88	A	H	0.0000
89	V	H	0.3023
90	Y	H	0.0000
91	Y	H	0.0000
92	C	H	0.0000
93	A	H	0.0000
94	R	H	-0.2057
95	S	H	0.0000
96	S	H	0.3267
97	R	H	0.7915
98	I	H	1.8507
99	Y	H	1.4998
100	D	H	-0.7816
100A	L	H	-0.2702
100B	N	H	-1.2160
100C	P	H	-0.9857
100D	S	H	-0.4422
100E	L	H	0.0642
100F	T	H	-0.2896
100G	A	H	0.0000
100H	Y	H	0.4519
100I	Y	H	0.2923
100J	D	H	0.0000
100K	M	H	0.0000
101	D	H	-0.6511
102	V	H	-0.3634
103	W	H	-0.3986
104	G	H	0.0000
105	Q	H	-1.0992
106	G	H	-0.4614
107	T	H	0.0000
108	M	H	0.3624
109	V	H	0.0000
110	T	H	-0.2300
111	V	H	0.0000
112	S	H	-1.0794
2	S	L	-0.0078
3	V	L	0.9425
4	L	L	0.0000
5	T	L	-0.1001
6	Q	L	0.0000
7	P	L	-0.6004
8	P	L	-0.9023
10	S	L	-0.9898
11	V	L	-0.4000
12	S	L	-0.5291
13	A	L	0.0000
14	A	L	-0.9271
15	P	L	-1.4669
16	G	L	-1.7709
17	Q	L	-2.2706
18	K	L	-2.4895
19	V	L	0.0000
20	T	L	-0.4970
21	I	L	0.0000
22	S	L	-0.3188
23	C	L	0.0000
24	S	L	-0.2944
25	G	L	-0.2953
26	S	L	-0.5753
27	S	L	-0.9274
28	S	L	-0.6222
29	N	L	0.0000
30	I	L	0.0000
30A	G	L	-1.2519
30B	N	L	-1.4005
31	N	L	0.0000
32	Y	L	0.0690
33	V	L	0.0000
34	S	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	Q	L	0.0000
38	Q	L	0.0000
39	L	L	-0.4426
40	P	L	-0.5428
41	G	L	-0.4420
42	T	L	-0.5888
43	A	L	-0.5580
44	P	L	0.0000
45	K	L	-1.2333
46	L	L	0.0000
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	-0.3867
50	D	L	-1.2964
51	N	L	-1.5742
52	N	L	-2.4608
53	K	L	-2.6953
54	R	L	-1.7470
55	P	L	-0.7585
56	S	L	-0.5390
57	G	L	-0.7487
58	I	L	-0.8876
59	P	L	-1.2762
60	D	L	-2.3361
61	R	L	-1.6801
62	F	L	0.0000
63	S	L	-1.5074
64	G	L	-1.3301
65	S	L	-1.3595
66	K	L	-1.0920
67	S	L	-0.8323
68	G	L	-1.0759
69	T	L	-0.9730
70	S	L	-0.7234
71	A	L	0.0000
72	T	L	-0.5815
73	L	L	0.0000
74	G	L	-0.6213
75	I	L	0.0000
76	T	L	-1.8634
77	G	L	-1.7710
78	L	L	0.0000
79	Q	L	-1.9930
80	T	L	-1.4248
81	G	L	-1.3647
82	D	L	0.0000
83	E	L	-2.3952
84	A	L	0.0000
85	D	L	-1.3771
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	G	L	0.0000
90	T	L	0.0000
91	W	L	0.2293
92	D	L	0.0000
93	S	L	-0.2118
94	S	L	0.0540
95	L	L	0.4306
95A	S	L	-0.0206
95B	A	L	0.0000
96	W	L	0.0000
97	V	L	0.0000
98	F	L	0.0000
99	G	L	0.0000
100	G	L	-0.7651
101	G	L	-1.0230
102	T	L	0.0000
103	K	L	-2.2914
104	L	L	0.0000
105	T	L	-0.8645
106	V	L	-0.7966
107	L	L	0.1365
108	R	L	-1.3033
109	T	L	-0.7405