Project name: 6ayn;A

Chain sequence(s)	A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEEQLKSGTASVVCLLNNFYPRREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.6206
• Maximal score value: 1.7608
• Average score: -0.8246
• Total score value: -174.8148

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	A	-1.3976
2	I	A	0.0000
3	L	A	0.7455
4	L	A	0.0000
5	T	A	-0.3405
6	Q	A	-0.1477
7	S	A	-0.0132
8	P	A	0.7393
9	V	A	1.7608
10	I	A	1.1457
11	L	A	0.4220
12	S	A	-0.4481
13	V	A	0.0000
14	S	A	-1.8086
15	P	A	-1.9740
16	G	A	-2.2667
17	E	A	-2.8695
18	R	A	-3.1818
19	V	A	0.0000
20	S	A	-0.7336
21	F	A	0.0000
22	S	A	-0.9099
23	C	A	0.0000
24	R	A	-2.7085
25	A	A	0.0000
26	S	A	-1.1392
27	Q	A	-1.7852
28	S	A	-1.6373
29	I	A	0.0000
30	G	A	-1.0599
31	T	A	-0.7785
32	N	A	-0.9726
33	I	A	0.0000
34	H	A	0.0000
35	W	A	0.0000
36	Y	A	0.0018
37	Q	A	0.0000
38	Q	A	-1.5899
39	R	A	-2.4443
40	T	A	-1.9899
41	N	A	-2.0462
42	G	A	-1.6279
43	S	A	-1.1033
44	P	A	-0.9985
45	R	A	-0.6895
46	L	A	-0.0575
47	L	A	0.0000
48	I	A	0.0000
49	K	A	-0.9785
50	Y	A	-0.4314
51	A	A	0.0000
52	S	A	-1.1959
53	E	A	-1.9755
54	S	A	-1.1428
55	I	A	-0.4974
56	S	A	-0.2476
57	G	A	-0.4043
58	I	A	-0.1571
59	P	A	-0.3101
60	S	A	-0.6267
61	R	A	-1.3057
62	F	A	0.0000
63	S	A	-0.9722
64	G	A	0.0000
65	S	A	-0.8136
66	G	A	-1.1320
67	S	A	-1.1602
68	G	A	-1.4398
69	T	A	-2.1369
70	D	A	-2.9391
71	F	A	0.0000
72	T	A	-0.9245
73	L	A	0.0000
74	S	A	0.0000
75	I	A	0.0000
76	N	A	-2.8007
77	S	A	-2.5116
78	V	A	0.0000
79	E	A	-2.8817
80	S	A	0.0000
81	E	A	-2.7952
82	D	A	0.0000
83	I	A	-1.8910
84	A	A	0.0000
85	D	A	-1.0112
86	Y	A	0.0000
87	Y	A	0.1733
88	C	A	0.0000
89	Q	A	0.3186
90	Q	A	0.0000
91	N	A	-1.2422
92	N	A	-1.4934
93	N	A	-1.1916
94	W	A	0.1128
95	P	A	-0.1168
96	T	A	-0.4245
97	T	A	0.3530
98	F	A	1.5043
99	G	A	0.6641
100	A	A	0.6946
101	G	A	0.2967
102	T	A	0.0000
103	K	A	-0.4498
104	L	A	0.0000
105	E	A	-1.0582
106	L	A	0.0000
107	K	A	-1.5845
108	R	A	-1.2063
109	T	A	-0.2153
110	V	A	0.1567
111	A	A	-0.0111
112	A	A	-0.1964
113	P	A	0.0000
114	S	A	-0.0183
115	V	A	0.4520
116	F	A	1.4516
117	I	A	1.3628
118	F	A	1.4828
119	P	A	-0.0368
120	P	A	-0.7268
121	S	A	-1.8577
122	D	A	-3.2597
123	E	A	-3.4531
124	Q	A	-2.5170
125	L	A	-2.5916
126	K	A	-3.0520
127	S	A	-1.9171
128	G	A	-1.3468
129	T	A	-1.1714
130	A	A	0.0000
131	S	A	0.0290
132	V	A	0.0000
133	V	A	0.7146
134	C	A	0.0000
135	L	A	0.5890
136	L	A	0.0000
137	N	A	-0.5104
138	N	A	-1.2397
139	F	A	0.0000
140	Y	A	-1.2668
141	P	A	-1.7530
142	R	A	-2.8897
143	E	A	-3.2192
144	A	A	-2.3175
145	K	A	-2.1559
146	V	A	-1.1327
147	Q	A	-0.6876
148	W	A	0.0000
149	K	A	-0.6436
150	V	A	0.0000
151	D	A	-1.9082
152	N	A	-1.4906
153	A	A	-0.2576
154	L	A	0.6841
155	Q	A	-0.1408
156	S	A	-0.4266
157	G	A	-1.0518
158	N	A	-1.0507
159	S	A	-1.4695
160	Q	A	-2.3182
161	E	A	-2.3465
162	S	A	-1.3640
163	V	A	-0.8690
164	T	A	-1.2668
165	E	A	-2.4902
166	Q	A	0.0000
167	D	A	-2.3429
168	S	A	-2.7019
169	K	A	-2.9320
170	D	A	-2.1892
171	S	A	0.0000
172	T	A	0.0000
173	Y	A	0.0000
174	S	A	-1.0014
175	L	A	0.0000
176	S	A	-0.4695
177	S	A	0.0000
178	T	A	-0.6143
179	L	A	0.0000
180	T	A	-0.4056
181	L	A	-0.7150
182	S	A	-1.2445
183	K	A	-2.0791
184	A	A	-1.9455
185	D	A	-2.6759
186	Y	A	0.0000
187	E	A	-3.3109
188	K	A	-3.6206
189	H	A	-3.0720
190	K	A	-3.1665
191	V	A	-1.5395
192	Y	A	0.0000
193	A	A	0.0000
194	C	A	0.0000
195	E	A	-0.9978
196	V	A	0.0000
197	T	A	-1.2718
198	H	A	0.0000
199	Q	A	-1.5771
200	G	A	-0.4438
201	L	A	-0.2106
202	S	A	-0.4421
203	S	A	-0.4416
204	P	A	-0.7083
205	V	A	-0.1905
206	T	A	-0.4691
207	K	A	-0.3759
208	S	A	-0.3798
209	F	A	-0.7170
210	N	A	-1.9865
211	R	A	-2.3204
212	G	A	-1.3042