Project name: a09b501569fe552

Chain sequence(s)	A: AQVLTQTASSVSAAVGGTVTISCQSSQSVYNKNWLGWYQQKPGQPPRLLIYGASTLASGVPSRFSGSGSGTQFTLTISDVQCDDAATYYCAGGYSNNIVSFGGGTRVVVEVATLAPTVLIFPPSPAELATGTATIVCVANKYFPDGTVTWQVDGKPLTTGIETSKTPQNSDDCTYNLSSTLTLKSDEYNSHDEYTCQVAQGSGSPVVQSFNRGDCGGGSICGGGGSGGGGSGGGGSGGGGSDYKDDDDK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.9911
• Maximal score value: 2.0027
• Average score: -0.6399
• Total score value: -159.33

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	-0.1952
2	Q	A	0.3440
3	V	A	1.3269
4	L	A	0.0000
5	T	A	-0.2345
6	Q	A	0.0000
7	T	A	-0.4206
8	A	A	-0.0921
9	S	A	-0.3134
10	S	A	-0.0270
11	V	A	0.5287
12	S	A	0.4074
13	A	A	0.3004
14	A	A	0.3527
15	V	A	-0.0791
16	G	A	-0.6538
17	G	A	-0.5297
18	T	A	-0.5511
19	V	A	0.0035
20	T	A	0.0096
21	I	A	0.0000
22	S	A	-0.4661
23	C	A	0.0000
24	Q	A	-1.2103
25	S	A	0.0000
26	S	A	-0.6081
27	Q	A	-0.8933
28	S	A	-0.2076
29	V	A	0.6291
30	Y	A	0.6080
31	N	A	-1.1381
32	K	A	-1.7566
33	N	A	0.0000
34	W	A	0.2407
35	L	A	0.0000
36	G	A	0.6749
37	W	A	0.0000
38	Y	A	-0.0554
39	Q	A	-0.8526
40	Q	A	-1.3705
41	K	A	-1.6634
42	P	A	-1.1868
43	G	A	-1.3756
44	Q	A	-2.1123
45	P	A	-1.5847
46	P	A	-1.5107
47	R	A	-1.8520
48	L	A	-0.0709
49	L	A	0.0000
50	I	A	0.0000
51	Y	A	1.1556
52	G	A	0.2788
53	A	A	0.0000
54	S	A	0.0272
55	T	A	0.2577
56	L	A	0.4923
57	A	A	0.1414
58	S	A	-0.2155
59	G	A	-0.4114
60	V	A	-0.3571
61	P	A	-0.5620
62	S	A	-0.7287
63	R	A	-1.2242
64	F	A	0.0000
65	S	A	-0.4653
66	G	A	-0.2101
67	S	A	-0.4380
68	G	A	-0.8384
69	S	A	-1.1673
70	G	A	-1.0000
71	T	A	-1.0774
72	Q	A	-1.1429
73	F	A	0.0000
74	T	A	-0.5099
75	L	A	0.0000
76	T	A	-0.3664
77	I	A	0.0000
78	S	A	-1.0179
79	D	A	-1.2937
80	V	A	0.0000
81	Q	A	-1.7474
82	C	A	-1.9864
83	D	A	-2.7467
84	D	A	0.0000
85	A	A	-1.1443
86	A	A	0.0000
87	T	A	-0.2468
88	Y	A	0.0000
89	Y	A	-0.0633
90	C	A	0.0000
91	A	A	0.7759
92	G	A	0.0000
93	G	A	0.1476
94	Y	A	0.2309
95	S	A	-0.3243
96	N	A	-1.2592
97	N	A	-0.7624
98	I	A	1.1735
99	V	A	0.9403
100	S	A	0.4603
101	F	A	0.0000
102	G	A	-0.3344
103	G	A	-0.3450
104	G	A	0.0000
105	T	A	-0.0656
106	R	A	0.0000
107	V	A	0.5084
108	V	A	0.0000
109	V	A	1.1019
110	E	A	0.5098
111	V	A	1.8082
112	A	A	1.2290
113	T	A	0.6624
114	L	A	0.7677
115	A	A	0.0000
116	P	A	-0.0654
117	T	A	0.7275
118	V	A	1.5384
119	L	A	0.0000
120	I	A	1.6432
121	F	A	1.0000
122	P	A	0.2256
123	P	A	-0.1198
124	S	A	-0.3258
125	P	A	-0.1460
126	A	A	-0.2530
127	E	A	-0.7059
128	L	A	1.0388
129	A	A	0.2493
130	T	A	-0.7809
131	G	A	-1.2140
132	T	A	0.0000
133	A	A	0.0307
134	T	A	0.0000
135	I	A	1.0113
136	V	A	0.0000
137	C	A	0.4625
138	V	A	0.0000
139	A	A	-0.5582
140	N	A	-1.4171
141	K	A	0.0000
142	Y	A	0.3578
143	F	A	0.6836
144	P	A	-0.9471
145	D	A	-1.6742
146	G	A	-1.0082
147	T	A	-0.5525
148	V	A	0.0647
149	T	A	0.1281
150	W	A	0.0000
151	Q	A	-1.6611
152	V	A	0.0000
153	D	A	-3.2866
154	G	A	-2.5447
155	K	A	-2.6749
156	P	A	-1.4190
157	L	A	-0.5509
158	T	A	-0.3713
159	T	A	-0.2885
160	G	A	-0.5154
161	I	A	-0.4996
162	E	A	-1.7258
163	T	A	-1.2513
164	S	A	-1.5966
165	K	A	-2.0184
166	T	A	-1.3921
167	P	A	-1.2584
168	Q	A	-1.5758
169	N	A	-2.8067
170	S	A	-2.7504
171	D	A	-3.5256
172	D	A	-3.4906
173	C	A	0.0000
174	T	A	-1.4254
175	Y	A	0.0000
176	N	A	-1.4299
177	L	A	0.0000
178	S	A	-0.5382
179	S	A	0.0000
180	T	A	-0.2530
181	L	A	0.0000
182	T	A	-0.6984
183	L	A	-1.4633
184	K	A	-2.8159
185	S	A	0.0000
186	D	A	-3.5216
187	E	A	-3.3903
188	Y	A	0.0000
189	N	A	-2.7781
190	S	A	-2.3747
191	H	A	-2.8045
192	D	A	-2.9768
193	E	A	-2.8670
194	Y	A	0.0000
195	T	A	0.0000
196	C	A	0.0000
197	Q	A	0.2259
198	V	A	0.0000
199	A	A	-0.3953
200	Q	A	-0.6668
201	G	A	-0.7505
202	S	A	-0.3809
203	G	A	-0.7109
204	S	A	-0.2251
205	P	A	0.0361
206	V	A	0.7573
207	V	A	1.5086
208	Q	A	0.8988
209	S	A	0.3930
210	F	A	-0.3975
211	N	A	-2.1572
212	R	A	-2.3328
213	G	A	-2.2993
214	D	A	-2.7474
215	C	A	-1.5705
216	G	A	-1.5667
217	G	A	-1.2236
218	G	A	-0.5917
219	S	A	0.2965
220	I	A	2.0027
221	C	A	1.2304
222	G	A	-0.1913
223	G	A	-0.8354
224	G	A	-1.1244
225	G	A	-1.2069
226	S	A	-1.0594
227	G	A	-1.2403
228	G	A	-1.1729
229	G	A	-1.1183
230	G	A	-1.0113
231	S	A	-0.8690
232	G	A	-1.0584
233	G	A	-1.1003
234	G	A	-1.1405
235	G	A	-1.0089
236	S	A	-0.9673
237	G	A	-1.0655
238	G	A	-1.0950
239	G	A	-1.3273
240	G	A	-1.2152
241	S	A	-1.4044
242	D	A	-2.1422
243	Y	A	-2.1715
244	K	A	-4.3977
245	D	A	-4.6059
246	D	A	-4.6133
247	D	A	-4.9911
248	D	A	-4.6958
249	K	A	-3.7175