Project name: 4kaq:L

Chain sequence(s)	L: VLSQSPAILSASPGEKVTMTCRASSSVSYIHWFQQKPGSSPKPWIYATSNLASGVPVRFSGSSGSGTSYSLTISRVEAEDAATYYCQQWTSNPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPRREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADDYEKHKVYACEVTHQGLSSPVTKSFNRGEC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.6104
• Maximal score value: 1.6528
• Average score: -0.7501
• Total score value: -158.279

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
3	V	L	1.5774
4	L	L	0.5106
5	S	L	-0.4254
6	Q	L	-0.6052
7	S	L	-0.3387
8	P	L	0.2399
9	A	L	0.4208
10	I	L	1.2074
11	L	L	0.4120
12	S	L	-0.5877
13	A	L	0.0000
14	S	L	-2.2705
15	P	L	-2.4594
16	G	L	-3.0091
17	E	L	-3.4913
18	K	L	-3.4085
19	V	L	0.0000
20	T	L	-0.4503
21	M	L	0.0000
22	T	L	-0.6463
23	C	L	0.0000
24	R	L	-1.6542
25	A	L	-0.5536
26	S	L	-0.1654
27	S	L	-0.3407
28	S	L	-0.5969
29	V	L	0.0417
30	S	L	0.3761
31	Y	L	1.0485
32	I	L	0.0000
33	H	L	0.6241
34	W	L	0.0000
35	F	L	0.0000
36	Q	L	0.0000
37	Q	L	-1.2390
38	K	L	-1.7630
39	P	L	-1.2955
40	G	L	-1.1072
41	S	L	-1.0108
42	S	L	-0.9870
43	P	L	-1.1191
44	K	L	-1.4478
45	P	L	-0.4895
46	W	L	-0.2905
47	I	L	0.0000
48	Y	L	0.5102
49	A	L	0.2792
50	T	L	-0.0167
51	S	L	-0.5196
52	N	L	-0.8943
53	L	L	0.2578
54	A	L	-0.2139
55	S	L	-0.4300
56	G	L	-0.2409
57	V	L	0.0000
58	P	L	0.6689
59	V	L	1.6528
60	R	L	-0.1506
61	F	L	0.0000
62	S	L	-0.0952
63	G	L	-0.4326
64	S	L	-0.5363
65	G	L	-0.6047
66	S	L	-0.5481
67	G	L	-0.6019
68	T	L	-0.8471
69	S	L	-1.0239
70	Y	L	0.0000
71	S	L	-0.5805
72	L	L	0.0000
73	T	L	-0.7422
74	I	L	0.0000
75	S	L	-1.9860
76	R	L	-3.5890
77	V	L	0.0000
78	E	L	-3.3203
79	A	L	-2.7480
80	E	L	-3.0713
81	D	L	0.0000
82	A	L	-2.1080
83	A	L	0.0000
84	T	L	0.0000
85	Y	L	0.0000
86	Y	L	-0.0505
87	C	L	0.0000
88	Q	L	0.0000
89	Q	L	0.0000
90	W	L	1.0199
91	T	L	0.2218
92	S	L	-0.4461
93	N	L	-1.3086
94	P	L	-0.7165
95	P	L	0.2636
96	T	L	0.9258
97	F	L	1.5619
98	G	L	0.4211
99	G	L	-0.2142
100	G	L	-0.2013
101	T	L	0.0000
102	K	L	-0.9496
103	L	L	0.0000
104	E	L	-1.4119
105	I	L	0.0000
106	K	L	-1.8771
107	R	L	-1.1942
108	T	L	-0.0405
109	V	L	0.5238
110	A	L	-0.0617
111	A	L	-0.1866
112	P	L	0.0000
113	S	L	-0.1655
114	V	L	0.0000
115	F	L	0.9751
116	I	L	1.0823
117	F	L	1.4090
118	P	L	0.0903
119	P	L	-0.9416
120	S	L	-1.8265
121	D	L	-3.2754
122	E	L	-3.4672
123	Q	L	-2.4839
124	L	L	-2.3660
125	K	L	-3.0645
126	S	L	-1.9463
127	G	L	-1.5193
128	T	L	-1.4218
129	A	L	0.0000
130	S	L	0.0143
131	V	L	0.0000
132	V	L	0.6771
133	C	L	0.0000
134	L	L	0.3904
135	L	L	0.0000
136	N	L	-0.6045
137	N	L	-1.3242
138	F	L	0.0000
139	Y	L	0.0000
140	P	L	-1.7818
141	R	L	-2.9646
142	E	L	-3.2006
143	A	L	-2.2708
144	K	L	-2.2056
145	V	L	-1.1532
146	Q	L	-0.6871
147	W	L	0.0000
148	K	L	-0.5893
149	V	L	0.0000
150	D	L	-1.7231
151	N	L	-1.4978
152	A	L	-0.2475
153	L	L	0.7058
154	Q	L	-0.1760
155	S	L	-0.4079
156	G	L	-0.9807
157	N	L	-0.9162
158	S	L	-1.3985
159	Q	L	-2.2759
160	E	L	-2.3282
161	S	L	-1.1167
162	V	L	-0.8790
163	T	L	-1.2520
164	E	L	-2.4202
165	Q	L	-2.4046
166	D	L	-2.4278
167	S	L	-2.6868
168	K	L	-2.9388
169	D	L	-2.2476
170	S	L	0.0000
171	T	L	0.0000
172	Y	L	0.0000
173	S	L	-1.0099
174	L	L	0.0000
175	S	L	-0.4848
176	S	L	0.0000
177	T	L	-0.6178
178	L	L	0.0000
179	T	L	-0.5105
180	L	L	-0.7562
181	S	L	-1.1570
182	K	L	-2.1911
183	A	L	-1.9330
184	D	L	-2.8542
185	Y	L	0.0000
186	E	L	-3.5346
187	K	L	-3.6104
188	H	L	-3.0644
189	K	L	-3.2932
190	V	L	-1.5080
191	Y	L	0.0000
192	A	L	0.0000
193	C	L	0.0000
194	E	L	-0.7705
195	V	L	0.0000
196	T	L	-1.1194
197	H	L	0.0000
198	Q	L	-1.6961
199	G	L	-0.3688
200	L	L	-0.1672
201	S	L	-0.4226
202	S	L	-0.3660
203	P	L	-0.4686
204	V	L	0.0239
205	T	L	-0.5241
206	K	L	-0.6683
207	S	L	-0.5470
208	F	L	-0.6983
209	N	L	-1.8244
210	R	L	-2.4117
211	G	L	-1.9821
212	E	L	-2.1667
213	C	L	-0.3881