Project name: 12_w

Chain sequence(s)	A: KTSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQ
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.5257
• Maximal score value: 0.6681
• Average score: -1.1046
• Total score value: -185.5673

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
102	K	A	-2.6354
103	T	A	-1.7452
104	S	A	0.0000
105	D	A	0.0000
106	L	A	0.0000
107	I	A	0.0000
108	V	A	0.0000
109	L	A	0.0000
110	G	A	0.0000
111	L	A	0.0000
112	P	A	-0.6679
113	W	A	-0.3444
114	K	A	-1.6933
115	T	A	-1.5971
116	T	A	-1.3729
117	E	A	-1.7874
118	Q	A	-2.3865
119	D	A	-2.4571
120	L	A	0.0000
121	K	A	-2.3100
122	E	A	-2.6864
123	Y	A	-1.3054
124	F	A	0.0000
125	S	A	-1.1502
126	T	A	-0.5948
127	F	A	-0.4424
128	G	A	-1.2672
129	E	A	-1.8219
130	V	A	0.0000
131	L	A	0.6681
132	M	A	0.0000
133	V	A	0.0000
134	Q	A	-0.7372
135	V	A	-0.5608
136	K	A	-0.8421
137	K	A	-1.5058
138	D	A	-1.1499
139	L	A	-0.1889
140	K	A	-1.4334
141	T	A	-1.2296
142	G	A	-1.1768
143	H	A	-1.7373
144	S	A	-1.2434
145	K	A	-1.0963
146	G	A	0.0000
147	F	A	0.0000
148	G	A	0.0000
149	F	A	0.0000
150	V	A	0.0000
151	R	A	-0.2744
152	F	A	0.0000
153	T	A	-1.2046
154	E	A	-2.4688
155	Y	A	-1.7732
156	E	A	-2.1780
157	T	A	0.0000
158	Q	A	0.0000
159	V	A	-0.7377
160	K	A	-1.0319
161	V	A	0.0000
162	M	A	-0.8593
163	S	A	-1.2161
164	Q	A	-2.2199
165	R	A	-2.1286
166	H	A	0.0000
167	M	A	-0.2053
168	I	A	0.0000
169	D	A	-2.3331
170	G	A	-1.4148
171	R	A	-1.0582
172	W	A	0.0619
173	C	A	0.0000
174	D	A	-0.9306
175	C	A	0.0000
176	K	A	-1.2993
177	L	A	-0.5920
178	P	A	0.0000
179	N	A	-1.5719
180	S	A	-1.1034
181	K	A	0.0000
182	Q	A	-2.0402
183	S	A	-1.9106
184	Q	A	-2.9223
185	D	A	-3.5199
186	E	A	-2.8134
187	P	A	-1.3468
188	L	A	-0.2594
189	R	A	-2.4402
190	S	A	-3.0446
191	R	A	-2.8114
192	K	A	-2.1364
193	V	A	0.0000
194	F	A	-0.2036
195	V	A	0.0000
196	G	A	0.0000
197	R	A	-0.3843
198	C	A	0.0000
199	T	A	-1.3742
200	E	A	-2.5037
201	D	A	-3.0276
202	M	A	0.0000
203	T	A	-1.9034
204	E	A	-2.0136
205	D	A	-3.2406
206	E	A	-3.0212
207	L	A	0.0000
208	R	A	-3.0663
209	E	A	-3.2674
210	F	A	-1.8722
211	F	A	0.0000
212	S	A	-1.6324
213	Q	A	-1.6900
214	Y	A	-0.4580
215	G	A	-1.3047
216	D	A	-1.9762
217	V	A	0.0000
218	M	A	-0.7441
219	D	A	-1.8494
220	V	A	-1.1797
221	F	A	-0.0367
222	I	A	0.0000
223	P	A	0.0000
224	K	A	-1.6708
225	P	A	-1.3524
226	F	A	-0.8428
227	R	A	-0.6987
228	A	A	0.0000
229	F	A	0.0000
230	A	A	0.0000
231	F	A	0.0000
232	V	A	0.0000
233	T	A	-1.2292
234	F	A	0.0000
235	A	A	-1.5773
236	D	A	-2.4919
237	D	A	-3.5257
238	Q	A	-2.8768
239	I	A	-1.8918
240	A	A	0.0000
241	Q	A	-2.2163
242	S	A	-1.3915
243	L	A	0.0000
244	C	A	0.0000
245	G	A	-1.9052
246	E	A	-2.1172
247	D	A	0.0000
248	L	A	0.0000
249	I	A	-0.1846
250	I	A	0.0000
251	K	A	-2.0132
252	G	A	-0.9177
253	I	A	0.0000
254	S	A	0.0000
255	V	A	0.0000
256	H	A	-0.5190
257	I	A	0.0000
258	S	A	-0.6869
259	N	A	-1.2402
260	A	A	0.0000
261	E	A	-2.7290
262	P	A	-2.5568
263	K	A	-2.5309
264	H	A	-2.3727
265	N	A	-2.9383
266	S	A	-2.7198
267	N	A	-3.2974
268	R	A	-3.3625
269	Q	A	-2.6781