Project name: 5vl3:L
Status: done
submitted: 2019-03-20 20:38:27, status changed: 2019-03-20 20:48:06
Settings
|
Chain sequence(s)
|
L: DIQLTQSPSSLSASVGDRVTMSCKSSQSVLYSANHKNYLAWYQQKPGKAPKLLIYWASTRESGVPSRFSGSGSGTDFTLTISSLQPEDIATYYCHQYLSSWTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKS
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
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Minimal score value
-
-3.7164
-
Maximal score value
-
1.3161
-
Average score
-
-0.7865
-
Total score value
-
-167.5208
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.9359 |
|
| 2 |
I |
L |
-1.0503 |
|
| 3 |
Q |
L |
-1.6710 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
T |
L |
-1.0899 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.8021 |
|
| 8 |
P |
L |
-0.5822 |
|
| 9 |
S |
L |
-0.7926 |
|
| 10 |
S |
L |
-0.7780 |
|
| 11 |
L |
L |
-0.4692 |
|
| 12 |
S |
L |
-0.6908 |
|
| 13 |
A |
L |
-0.7797 |
|
| 14 |
S |
L |
-0.5742 |
|
| 15 |
V |
L |
0.3767 |
|
| 16 |
G |
L |
-0.7511 |
|
| 17 |
D |
L |
-1.5536 |
|
| 18 |
R |
L |
-2.2885 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.5879 |
|
| 21 |
M |
L |
0.0000 |
|
| 22 |
S |
L |
-0.8907 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
K |
L |
-2.6205 |
|
| 25 |
S |
L |
0.0000 |
|
| 26 |
S |
L |
-1.8163 |
|
| 27 |
Q |
L |
-1.9887 |
|
| 27A |
S |
L |
-0.8883 |
|
| 27B |
V |
L |
0.0000 |
|
| 27C |
L |
L |
0.1738 |
|
| 27D |
Y |
L |
0.4546 |
|
| 27E |
S |
L |
-0.2299 |
|
| 27F |
A |
L |
-0.4364 |
|
| 28 |
N |
L |
-1.0739 |
|
| 29 |
H |
L |
-1.2368 |
|
| 30 |
K |
L |
-0.8910 |
|
| 31 |
N |
L |
0.0000 |
|
| 32 |
Y |
L |
0.5342 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
A |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.2614 |
|
| 37 |
Q |
L |
-0.8904 |
|
| 38 |
Q |
L |
-1.6060 |
|
| 39 |
K |
L |
-1.8788 |
|
| 40 |
P |
L |
-1.5889 |
|
| 41 |
G |
L |
-1.6076 |
|
| 42 |
K |
L |
-2.5163 |
|
| 43 |
A |
L |
-1.5468 |
|
| 44 |
P |
L |
-1.5306 |
|
| 45 |
K |
L |
-1.9213 |
|
| 46 |
L |
L |
-0.6640 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
0.2195 |
|
| 50 |
W |
L |
0.2137 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
-0.5678 |
|
| 53 |
T |
L |
-0.5611 |
|
| 54 |
R |
L |
-1.2202 |
|
| 55 |
E |
L |
-1.3505 |
|
| 56 |
S |
L |
-1.0251 |
|
| 57 |
G |
L |
-0.9478 |
|
| 58 |
V |
L |
0.0000 |
|
| 59 |
P |
L |
-0.6546 |
|
| 60 |
S |
L |
-0.6129 |
|
| 61 |
R |
L |
-0.7866 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.5382 |
|
| 64 |
G |
L |
-0.4166 |
|
| 65 |
S |
L |
-0.6695 |
|
| 66 |
G |
L |
-1.1403 |
|
| 67 |
S |
L |
-1.0757 |
|
| 68 |
G |
L |
-1.0048 |
|
| 69 |
T |
L |
-1.6374 |
|
| 70 |
D |
L |
-2.2735 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.7993 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.5812 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.3140 |
|
| 77 |
S |
L |
-1.1972 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-1.1607 |
|
| 80 |
P |
L |
-0.9780 |
|
| 81 |
E |
L |
-2.0124 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
I |
L |
-0.5783 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
0.0000 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.0531 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
H |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
Y |
L |
1.0274 |
|
| 92 |
L |
L |
0.9816 |
|
| 93 |
S |
L |
0.2969 |
|
| 94 |
S |
L |
0.3292 |
|
| 96 |
W |
L |
1.2331 |
|
| 97 |
T |
L |
0.6699 |
|
| 98 |
F |
L |
1.1785 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
G |
L |
-0.5371 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-1.4560 |
|
| 104 |
L |
L |
0.0000 |
|
| 105 |
E |
L |
-1.0675 |
|
| 106 |
I |
L |
-0.6131 |
|
| 107 |
K |
L |
-1.2526 |
|
| 108 |
R |
L |
-1.0197 |
|
| 109 |
T |
L |
-0.1663 |
|
| 110 |
V |
L |
0.3376 |
|
| 112 |
A |
L |
0.0271 |
|
| 113 |
A |
L |
-0.2542 |
|
| 114 |
P |
L |
0.0000 |
|
| 115 |
S |
L |
-0.1509 |
|
| 116 |
V |
L |
0.0000 |
|
| 117 |
F |
L |
0.9905 |
|
| 118 |
I |
L |
1.0240 |
|
| 119 |
F |
L |
1.3161 |
|
| 120 |
P |
L |
0.1673 |
|
| 121 |
P |
L |
-0.6898 |
|
| 122 |
S |
L |
-1.9812 |
|
| 123 |
D |
L |
-3.4214 |
|
| 124 |
E |
L |
-3.7164 |
|
| 125 |
Q |
L |
-3.0530 |
|
| 126 |
L |
L |
-2.6379 |
|
| 127 |
K |
L |
-3.2402 |
|
| 128 |
S |
L |
-2.1299 |
|
| 129 |
G |
L |
-1.4822 |
|
| 130 |
T |
L |
-1.2112 |
|
| 131 |
A |
L |
0.0000 |
|
| 132 |
S |
L |
-0.0428 |
|
| 133 |
V |
L |
0.0000 |
|
| 134 |
V |
L |
0.6538 |
|
| 135 |
C |
L |
0.0000 |
|
| 136 |
L |
L |
0.4449 |
|
| 137 |
L |
L |
0.0000 |
|
| 138 |
N |
L |
-0.6923 |
|
| 139 |
N |
L |
-1.5403 |
|
| 140 |
F |
L |
0.0000 |
|
| 141 |
Y |
L |
0.0000 |
|
| 142 |
P |
L |
-1.7315 |
|
| 143 |
R |
L |
-2.8578 |
|
| 144 |
E |
L |
-3.1160 |
|
| 145 |
A |
L |
-2.2855 |
|
| 146 |
K |
L |
-2.2615 |
|
| 147 |
V |
L |
-1.1162 |
|
| 148 |
Q |
L |
-0.6353 |
|
| 149 |
W |
L |
0.0000 |
|
| 150 |
K |
L |
-0.4134 |
|
| 151 |
V |
L |
0.0000 |
|
| 152 |
D |
L |
-1.4696 |
|
| 153 |
N |
L |
-1.1780 |
|
| 154 |
A |
L |
-0.2604 |
|
| 155 |
L |
L |
0.3899 |
|
| 156 |
Q |
L |
-0.2234 |
|
| 157 |
S |
L |
-0.4744 |
|
| 158 |
G |
L |
-1.0111 |
|
| 159 |
N |
L |
-0.9746 |
|
| 160 |
S |
L |
-1.4358 |
|
| 161 |
Q |
L |
-2.3166 |
|
| 162 |
E |
L |
-2.3272 |
|
| 163 |
S |
L |
-1.3094 |
|
| 164 |
V |
L |
-0.6286 |
|
| 165 |
T |
L |
-1.1616 |
|
| 166 |
E |
L |
-2.4100 |
|
| 167 |
Q |
L |
-2.2728 |
|
| 168 |
D |
L |
-2.8171 |
|
| 169 |
S |
L |
-2.1715 |
|
| 170 |
K |
L |
-2.5998 |
|
| 171 |
D |
L |
-2.2482 |
|
| 172 |
S |
L |
-2.2241 |
|
| 173 |
T |
L |
0.0000 |
|
| 174 |
Y |
L |
0.0000 |
|
| 175 |
S |
L |
-1.0312 |
|
| 176 |
L |
L |
0.0000 |
|
| 177 |
S |
L |
-0.5293 |
|
| 178 |
S |
L |
0.0000 |
|
| 179 |
T |
L |
-0.6239 |
|
| 180 |
L |
L |
0.0000 |
|
| 181 |
T |
L |
-0.4351 |
|
| 182 |
L |
L |
-0.6020 |
|
| 183 |
S |
L |
-1.1288 |
|
| 184 |
K |
L |
-2.0285 |
|
| 185 |
A |
L |
-1.8837 |
|
| 186 |
D |
L |
-2.3500 |
|
| 187 |
Y |
L |
-2.3061 |
|
| 188 |
E |
L |
-3.5029 |
|
| 189 |
K |
L |
-3.6332 |
|
| 190 |
H |
L |
-2.7530 |
|
| 191 |
K |
L |
-2.2395 |
|
| 192 |
V |
L |
-0.3639 |
|
| 193 |
Y |
L |
-0.3232 |
|
| 194 |
A |
L |
0.0000 |
|
| 195 |
C |
L |
0.0000 |
|
| 196 |
E |
L |
-0.7838 |
|
| 197 |
V |
L |
0.0000 |
|
| 198 |
T |
L |
-1.1605 |
|
| 199 |
H |
L |
0.0000 |
|
| 200 |
Q |
L |
-1.6275 |
|
| 201 |
G |
L |
-0.4888 |
|
| 202 |
L |
L |
-0.2632 |
|
| 203 |
S |
L |
-0.4620 |
|
| 204 |
S |
L |
-0.4037 |
|
| 205 |
P |
L |
-0.4927 |
|
| 206 |
V |
L |
-0.0030 |
|
| 207 |
T |
L |
-0.4838 |
|
| 208 |
K |
L |
-0.6389 |
|
| 209 |
S |
L |
-0.1993 |
|