Project name: 5hys:H

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSCAVSGYSITSGYSWNWIRQAPGKGLEWVASITYDGSTNYNPSVKGRITISRDDSKNTFYLQMNSLRAEDTAVYYCARGSHYFGHWHFAVWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.1992
• Maximal score value: 2.5241
• Average score: -0.5927
• Total score value: -131.5815

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.1455
2	V	H	-1.3775
3	Q	H	-1.2989
4	L	H	0.0000
5	V	H	1.2188
6	E	H	0.0000
7	S	H	-0.3023
8	G	H	-1.1202
9	G	H	-0.8373
10	G	H	-0.4500
11	L	H	-0.3143
12	V	H	0.0000
13	Q	H	-1.5969
14	P	H	-1.4516
15	G	H	-1.4345
16	G	H	-1.3137
17	S	H	-1.8349
18	L	H	0.0000
19	R	H	-2.5736
20	L	H	0.0000
21	S	H	-0.6148
22	C	H	0.0000
23	A	H	-0.0772
24	V	H	0.0000
25	S	H	-0.9487
26	G	H	-1.2362
27	Y	H	-0.5203
28	S	H	-0.5554
29	I	H	0.0000
30	T	H	-0.7101
31	S	H	-0.1722
32	G	H	0.0000
33	Y	H	0.0747
34	S	H	0.0000
35	W	H	0.0000
36	N	H	0.0000
37	W	H	0.0000
38	I	H	0.0000
39	R	H	0.0000
40	Q	H	-0.4726
41	A	H	-1.1235
42	P	H	-1.2050
43	G	H	-1.4357
44	K	H	-2.0858
45	G	H	-0.9481
46	L	H	0.5463
47	E	H	-0.1556
48	W	H	0.2804
49	V	H	0.0000
50	A	H	0.0000
51	S	H	-0.5175
52	I	H	0.0000
53	T	H	-0.5115
54	Y	H	-0.1488
55	D	H	-1.5554
56	G	H	-1.1799
57	S	H	-0.9942
58	T	H	-0.9474
59	N	H	-1.5433
60	Y	H	-1.1236
61	N	H	-1.1497
62	P	H	-1.5121
63	S	H	-1.1659
64	V	H	0.0000
65	K	H	-2.8179
66	G	H	-2.4272
67	R	H	-3.1992
68	I	H	0.0000
69	T	H	-1.5722
70	I	H	0.0000
71	S	H	-0.7524
72	R	H	-1.3130
73	D	H	-2.1231
74	D	H	-2.8553
75	S	H	-2.1566
76	K	H	-2.6951
77	N	H	-2.0636
78	T	H	0.0000
79	F	H	0.0000
80	Y	H	0.0000
81	L	H	0.0000
82	Q	H	-2.1884
83	M	H	0.0000
84	N	H	-2.6494
85	S	H	-1.6958
86	L	H	0.0000
87	R	H	-1.7605
88	A	H	-1.3906
89	E	H	-2.0355
90	D	H	0.0000
91	T	H	-0.6653
92	A	H	0.0000
93	V	H	0.3351
94	Y	H	0.0000
95	Y	H	0.4359
96	C	H	0.0000
97	A	H	0.0000
98	R	H	-0.0969
99	G	H	0.0000
100	S	H	-0.3369
101	H	H	-0.2132
102	Y	H	1.2612
103	F	H	1.9046
104	G	H	0.2845
105	H	H	-0.4321
106	W	H	-0.1390
107	H	H	-0.7101
108	F	H	0.1043
109	A	H	0.1461
110	V	H	0.2836
111	W	H	0.4831
112	G	H	0.0348
113	Q	H	-0.7850
114	G	H	-0.1535
115	T	H	-0.0035
116	L	H	0.1787
117	V	H	0.0000
118	T	H	-0.3815
119	V	H	0.0000
120	S	H	-0.6698
121	S	H	-0.6557
122	A	H	-0.4669
123	S	H	-0.6346
124	T	H	-0.8413
125	K	H	-1.4622
126	G	H	-1.7234
127	P	H	0.0000
128	S	H	-0.1842
129	V	H	0.0000
130	F	H	1.0637
131	P	H	0.1694
132	L	H	0.2710
133	A	H	-0.9779
134	P	H	0.0000
135	S	H	-1.5487
136	S	H	-1.4701
137	K	H	-2.0739
138	S	H	-1.1750
139	T	H	-1.0215
140	S	H	-0.9578
141	G	H	-0.8800
142	G	H	-0.9270
143	T	H	-0.6394
144	A	H	0.0000
145	A	H	-0.1798
146	L	H	0.0000
147	G	H	0.0000
148	C	H	0.0000
149	L	H	0.7354
150	V	H	0.0000
151	K	H	-0.2890
152	D	H	-0.7675
153	Y	H	0.0000
154	F	H	0.0000
155	P	H	0.0000
156	E	H	-0.2849
157	P	H	-0.6311
158	V	H	-0.7514
159	T	H	-0.7237
160	V	H	-0.3934
161	S	H	-0.4419
162	W	H	0.0000
163	N	H	-0.7432
164	S	H	-0.6670
165	G	H	-0.5719
166	A	H	-0.2445
167	L	H	0.0225
168	T	H	-0.2893
169	S	H	-0.3173
170	G	H	-0.3648
171	V	H	-0.0566
172	H	H	-0.5184
173	T	H	0.1552
174	F	H	1.0749
175	P	H	0.7856
176	A	H	1.3264
177	V	H	2.5241
178	L	H	2.1122
179	Q	H	0.6689
180	S	H	0.0727
181	S	H	-0.2588
182	G	H	0.1379
183	L	H	0.2549
184	Y	H	0.7989
185	S	H	0.0000
186	L	H	0.0000
187	S	H	0.6694
188	S	H	0.0000
189	V	H	0.3617
190	V	H	0.0000
191	T	H	-0.2815
192	V	H	0.0000
193	P	H	-0.6790
194	S	H	-0.7296
195	S	H	-0.6235
196	S	H	-0.6880
197	L	H	-1.0168
198	G	H	-0.9948
199	T	H	-0.7433
200	Q	H	-1.2314
201	T	H	-1.0151
202	Y	H	0.0000
203	I	H	-1.1526
204	C	H	0.0000
205	N	H	-1.6691
206	V	H	0.0000
207	N	H	-2.3997
208	H	H	0.0000
209	K	H	-2.8487
210	P	H	-1.7114
211	S	H	-1.9388
212	N	H	-2.7354
213	T	H	-2.3089
214	K	H	-2.9089
215	V	H	-1.9278
216	D	H	-2.7654
217	K	H	-2.0572
218	K	H	-2.1169
219	V	H	0.0000
220	E	H	-2.6401
221	P	H	-1.7906
222	K	H	-2.3055