Project name: 5vzy:L
Status: done
submitted: 2019-03-20 20:38:56, status changed: 2019-03-20 20:49:58
Settings
|
Chain sequence(s)
|
L: DIVMTQSPLSLPVTPGEPASISCRSSQSLVYSNGDTYLHWYLQKPGQSPQLLIYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCSQSTHVPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.582
-
Maximal score value
-
1.7788
-
Average score
-
-0.8343
-
Total score value
-
-181.8796
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.0514 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
V |
L |
0.8524 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-0.2548 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.5581 |
|
| 8 |
P |
L |
-0.3622 |
|
| 9 |
L |
L |
-0.2063 |
|
| 10 |
S |
L |
-0.5319 |
|
| 11 |
L |
L |
-0.4923 |
|
| 12 |
P |
L |
-0.8331 |
|
| 13 |
V |
L |
0.0000 |
|
| 14 |
T |
L |
-1.7370 |
|
| 15 |
P |
L |
-2.0209 |
|
| 16 |
G |
L |
-2.4255 |
|
| 17 |
E |
L |
-3.1912 |
|
| 18 |
P |
L |
-2.6189 |
|
| 19 |
A |
L |
-1.4491 |
|
| 20 |
S |
L |
-0.8291 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
S |
L |
-1.0348 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.3445 |
|
| 25 |
S |
L |
0.0000 |
|
| 26 |
S |
L |
-1.0012 |
|
| 27 |
Q |
L |
-1.5214 |
|
| 27A |
S |
L |
-0.6102 |
|
| 27B |
L |
L |
0.0000 |
|
| 27C |
V |
L |
1.0529 |
|
| 27D |
Y |
L |
0.8105 |
|
| 27E |
S |
L |
-0.2954 |
|
| 28 |
N |
L |
-1.2899 |
|
| 29 |
G |
L |
-0.8163 |
|
| 30 |
D |
L |
-0.8185 |
|
| 31 |
T |
L |
0.0207 |
|
| 32 |
Y |
L |
0.2578 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
H |
L |
0.0511 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.0394 |
|
| 37 |
L |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.6802 |
|
| 39 |
K |
L |
-2.3209 |
|
| 40 |
P |
L |
-1.7991 |
|
| 41 |
G |
L |
-1.5209 |
|
| 42 |
Q |
L |
-2.1608 |
|
| 43 |
S |
L |
-1.5230 |
|
| 44 |
P |
L |
-1.3792 |
|
| 45 |
Q |
L |
-1.2825 |
|
| 46 |
L |
L |
-0.0730 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
-0.0336 |
|
| 50 |
K |
L |
-0.8469 |
|
| 51 |
V |
L |
-0.6158 |
|
| 52 |
S |
L |
-0.7894 |
|
| 53 |
N |
L |
-1.1466 |
|
| 54 |
R |
L |
-1.2853 |
|
| 55 |
F |
L |
0.1189 |
|
| 56 |
S |
L |
-0.2015 |
|
| 57 |
G |
L |
-0.6052 |
|
| 58 |
V |
L |
-0.5948 |
|
| 59 |
P |
L |
-1.1270 |
|
| 60 |
D |
L |
-2.3427 |
|
| 61 |
R |
L |
-2.0850 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-1.3839 |
|
| 64 |
G |
L |
-0.9116 |
|
| 65 |
S |
L |
-0.8201 |
|
| 66 |
G |
L |
-1.0020 |
|
| 67 |
S |
L |
-0.6899 |
|
| 68 |
G |
L |
-0.7290 |
|
| 69 |
T |
L |
-1.5256 |
|
| 70 |
D |
L |
-2.1847 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-1.0779 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
K |
L |
-1.7753 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-2.4374 |
|
| 77 |
R |
L |
-3.5820 |
|
| 78 |
V |
L |
0.0000 |
|
| 79 |
E |
L |
-2.7462 |
|
| 80 |
A |
L |
-1.5070 |
|
| 81 |
E |
L |
-2.2712 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
V |
L |
-1.1440 |
|
| 84 |
G |
L |
0.0000 |
|
| 85 |
V |
L |
0.0000 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.0344 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
S |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
S |
L |
0.7886 |
|
| 92 |
T |
L |
0.8277 |
|
| 93 |
H |
L |
0.5753 |
|
| 94 |
V |
L |
1.4991 |
|
| 95 |
P |
L |
1.0905 |
|
| 96 |
W |
L |
1.6092 |
|
| 97 |
T |
L |
1.3831 |
|
| 98 |
F |
L |
1.7788 |
|
| 99 |
G |
L |
0.2886 |
|
| 100 |
Q |
L |
-0.7490 |
|
| 101 |
G |
L |
-0.6365 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-1.8632 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-1.0872 |
|
| 106 |
I |
L |
-0.9487 |
|
| 107 |
K |
L |
-1.3880 |
|
| 108 |
R |
L |
-0.9497 |
|
| 109 |
T |
L |
-0.0754 |
|
| 110 |
V |
L |
0.2539 |
|
| 111 |
A |
L |
-0.1701 |
|
| 112 |
A |
L |
-0.2854 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1281 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.2356 |
|
| 117 |
I |
L |
1.1697 |
|
| 118 |
F |
L |
1.3773 |
|
| 119 |
P |
L |
-0.2236 |
|
| 120 |
P |
L |
-0.7571 |
|
| 121 |
S |
L |
-1.8252 |
|
| 122 |
D |
L |
-3.2742 |
|
| 123 |
E |
L |
-3.4924 |
|
| 124 |
Q |
L |
-2.5441 |
|
| 125 |
L |
L |
-2.5107 |
|
| 126 |
K |
L |
-3.1276 |
|
| 127 |
S |
L |
-1.9896 |
|
| 128 |
G |
L |
-1.4166 |
|
| 129 |
T |
L |
-1.4134 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0259 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7314 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.5176 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.5480 |
|
| 138 |
N |
L |
-1.3285 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.6779 |
|
| 142 |
R |
L |
-2.9058 |
|
| 143 |
E |
L |
-3.1453 |
|
| 144 |
A |
L |
-2.3198 |
|
| 145 |
K |
L |
-2.3036 |
|
| 146 |
V |
L |
-1.1148 |
|
| 147 |
Q |
L |
-0.6669 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.6164 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.8307 |
|
| 152 |
N |
L |
-1.4886 |
|
| 153 |
A |
L |
-0.2665 |
|
| 154 |
L |
L |
0.6834 |
|
| 155 |
Q |
L |
-0.2161 |
|
| 156 |
S |
L |
-0.5727 |
|
| 157 |
G |
L |
-1.0121 |
|
| 158 |
N |
L |
-0.9868 |
|
| 159 |
S |
L |
-1.4243 |
|
| 160 |
Q |
L |
-2.3108 |
|
| 161 |
E |
L |
-2.3230 |
|
| 162 |
S |
L |
-1.1151 |
|
| 163 |
V |
L |
-0.7039 |
|
| 164 |
T |
L |
-1.2344 |
|
| 165 |
E |
L |
-2.3154 |
|
| 166 |
Q |
L |
-2.1709 |
|
| 167 |
D |
L |
-2.4706 |
|
| 168 |
S |
L |
-1.9975 |
|
| 169 |
K |
L |
-2.5712 |
|
| 170 |
D |
L |
-2.2271 |
|
| 171 |
S |
L |
-2.0437 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
-1.6274 |
|
| 174 |
S |
L |
-0.9526 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.4306 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.6102 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.5180 |
|
| 181 |
L |
L |
-0.6693 |
|
| 182 |
S |
L |
-1.0196 |
|
| 183 |
K |
L |
-2.0269 |
|
| 184 |
A |
L |
-1.7459 |
|
| 185 |
D |
L |
-2.3690 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.1197 |
|
| 188 |
K |
L |
-3.3782 |
|
| 189 |
H |
L |
-2.8670 |
|
| 190 |
K |
L |
-3.0132 |
|
| 191 |
V |
L |
-1.4870 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.8074 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.1965 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.6110 |
|
| 200 |
G |
L |
-0.5041 |
|
| 201 |
L |
L |
-0.2986 |
|
| 202 |
S |
L |
-0.4747 |
|
| 203 |
S |
L |
-0.4093 |
|
| 204 |
P |
L |
-0.4859 |
|
| 205 |
V |
L |
0.0250 |
|
| 206 |
T |
L |
-0.3497 |
|
| 207 |
K |
L |
-0.3189 |
|
| 208 |
S |
L |
-0.3583 |
|
| 209 |
F |
L |
-0.8769 |
|
| 210 |
N |
L |
-2.0353 |
|
| 211 |
R |
L |
-2.5644 |
|
| 212 |
G |
L |
-2.1491 |
|
| 213 |
E |
L |
-2.3655 |
|