Project name: 6mi2:A

Chain sequence(s)	A: EVQLVQSGAEVKKPGESLRISCKGSGYSFSTYWISWVRQMPGKGLEWMGKIYPGDSYTNYSPSFQGQVTISADKSISTAYLQWSSLKASDTAMYYCARGYGIFDYWGQGTLVTVSSASTKGPSVFPLAPTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9225
• Maximal score value: 1.8743
• Average score: -0.4733
• Total score value: -98.9251

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.1828
2	V	A	-1.4061
3	Q	A	-1.4475
4	L	A	0.0000
5	V	A	0.4159
6	Q	A	-0.0793
7	S	A	-0.4939
8	G	A	-0.2330
9	A	A	0.3349
10	E	A	0.1408
11	V	A	1.2082
12	K	A	-0.6909
13	K	A	-1.9332
14	P	A	-1.9968
15	G	A	-1.8117
16	E	A	-1.7995
17	S	A	-1.6228
18	L	A	0.0000
19	R	A	-2.0907
20	I	A	0.0000
21	S	A	-0.7129
22	C	A	0.0000
23	K	A	-0.7854
24	G	A	0.0000
25	S	A	-0.8952
26	G	A	-1.3359
27	Y	A	-0.5330
28	S	A	-0.3236
29	F	A	0.0000
30	S	A	-0.7963
31	T	A	0.0462
32	Y	A	0.9225
33	W	A	1.0369
34	I	A	0.0000
35	S	A	0.0000
36	W	A	0.0000
37	V	A	0.0000
38	R	A	-0.4917
39	Q	A	-0.5870
40	M	A	-0.7686
41	P	A	-0.9625
42	G	A	-1.3700
43	K	A	-2.0730
44	G	A	-1.0341
45	L	A	0.3408
46	E	A	-0.6243
47	W	A	0.0308
48	M	A	0.0000
49	G	A	0.0000
50	K	A	0.2680
51	I	A	0.0000
52	Y	A	0.2657
53	P	A	0.0000
54	G	A	-1.1445
55	D	A	-1.7769
56	S	A	-0.8063
57	Y	A	0.6475
58	T	A	0.2288
59	N	A	-0.2492
60	Y	A	-0.6335
61	S	A	-0.6454
62	P	A	-0.8943
63	S	A	-0.9491
64	F	A	0.0000
65	Q	A	-1.8741
66	G	A	-1.5697
67	Q	A	-1.7470
68	V	A	0.0000
69	T	A	-0.9633
70	I	A	0.0000
71	S	A	-0.5821
72	A	A	-0.9921
73	D	A	-1.7787
74	K	A	-2.2046
75	S	A	-0.6840
76	I	A	0.2643
77	S	A	-0.7447
78	T	A	0.0000
79	A	A	0.0000
80	Y	A	-0.7617
81	L	A	0.0000
82	Q	A	-1.5343
83	W	A	0.0000
84	S	A	-1.2704
85	S	A	-1.5347
86	L	A	0.0000
87	K	A	-2.3395
88	A	A	-1.3448
89	S	A	-0.7914
90	D	A	0.0000
91	T	A	-0.0095
92	A	A	0.0000
93	M	A	0.3255
94	Y	A	0.0000
95	Y	A	0.3304
96	C	A	0.0000
97	A	A	0.0000
98	R	A	0.0000
99	G	A	1.2185
100	Y	A	1.6445
101	G	A	1.0435
102	I	A	1.8743
103	F	A	0.9677
104	D	A	-0.5077
105	Y	A	-0.0711
106	W	A	0.2459
107	G	A	0.0000
108	Q	A	-0.7483
109	G	A	-0.1099
110	T	A	0.0000
111	L	A	0.9990
112	V	A	0.0000
113	T	A	0.4609
114	V	A	0.0000
115	S	A	0.0000
116	S	A	-0.5914
117	A	A	-0.4901
118	S	A	-0.8200
119	T	A	-1.2810
120	K	A	-1.9018
121	G	A	-1.9112
122	P	A	0.0000
123	S	A	-0.1169
124	V	A	0.5377
125	F	A	1.5254
126	P	A	0.4792
127	L	A	0.4173
128	A	A	-0.7190
129	P	A	-0.5775
138	T	A	-0.3507
139	A	A	-0.1498
140	A	A	0.1349
141	L	A	0.0000
142	G	A	0.0000
143	C	A	0.0000
144	L	A	0.9021
145	V	A	0.0000
146	K	A	-0.6237
147	D	A	-1.2981
148	Y	A	0.0000
149	F	A	0.0000
150	P	A	-1.5668
151	E	A	-2.0410
152	P	A	-1.5636
153	V	A	-1.0022
154	T	A	-0.6183
155	V	A	-0.3474
156	S	A	-0.3752
157	W	A	0.0000
158	N	A	-0.8301
159	S	A	-0.6617
160	G	A	-0.6011
161	A	A	-0.2695
162	L	A	0.0430
163	T	A	-0.2601
164	S	A	-0.3617
165	G	A	-0.4568
166	V	A	-0.0620
167	H	A	-0.3041
168	T	A	0.3586
169	F	A	1.1587
170	P	A	0.6609
171	A	A	0.7660
172	V	A	1.8377
173	L	A	0.9119
174	Q	A	-0.1889
175	S	A	-0.2885
176	S	A	-0.5297
177	G	A	-0.3332
178	L	A	0.0000
179	Y	A	-0.2511
180	S	A	0.0000
181	L	A	0.0000
182	S	A	0.7283
183	S	A	0.0000
184	V	A	0.5800
185	V	A	0.0000
186	T	A	-0.2374
187	V	A	0.0000
188	P	A	-0.3529
189	S	A	-0.3176
190	S	A	-0.2989
191	S	A	-0.3480
192	L	A	-0.2591
193	G	A	-0.8042
194	T	A	-0.6653
195	Q	A	-1.2845
196	T	A	-1.1796
197	Y	A	-0.9221
198	I	A	-1.4588
199	C	A	0.0000
200	N	A	-1.3808
201	V	A	0.0000
202	N	A	-1.6795
203	H	A	0.0000
204	K	A	-2.9225
205	P	A	-2.0135
206	S	A	-1.9859
207	N	A	-2.4993
208	T	A	-2.0343
209	K	A	-2.3147
210	V	A	-1.0523
211	D	A	-2.1048
212	K	A	-2.1992
213	K	A	-2.3240
214	V	A	0.0000
215	E	A	-2.5974
216	P	A	-1.7516
217	K	A	-2.1514