Project name: a4a983aa6f2b1e1

Chain sequence(s)	A: ATKAVCVLKGDGPVQGIIINFEQKESNGPVKVWGSIKGLTEGLLHGFHVHEFGDNNTAGCTTSAGPHFNPLSRKHGGPKDEEEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCITGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ; F: ATKAVCVLKGGDDGGPPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEEFGDNNTAGCTTSAGPHFNPLSRKHGGPKDEEEERHVGDLGNVTADDKDGVADVSIEDSVISLSGDHCITGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.1805
• Maximal score value: 0.292
• Average score: -1.0416
• Total score value: -318.7391

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	-1.6501
2	T	A	-1.5742
3	K	A	-1.6854
4	A	A	0.0000
5	V	A	0.0000
6	C	A	0.0000
7	V	A	-0.2481
8	L	A	0.0000
9	K	A	-2.5194
10	G	A	-2.3871
11	D	A	-2.6687
12	G	A	-1.9163
13	P	A	-1.6603
14	V	A	0.0000
15	Q	A	-2.2235
16	G	A	0.0000
17	I	A	-0.0639
18	I	A	0.0000
19	N	A	-0.5199
20	F	A	0.0000
21	E	A	-2.2463
22	Q	A	0.0000
23	K	A	-3.2266
24	E	A	-3.2236
25	S	A	-2.2092
26	N	A	-2.2426
27	G	A	-1.9626
28	P	A	-1.7425
29	V	A	0.0000
30	K	A	-1.8680
31	V	A	0.0000
32	W	A	-0.5351
33	G	A	-0.3282
34	S	A	-0.9222
35	I	A	0.0000
36	K	A	-2.1113
37	G	A	-1.5609
38	L	A	0.0000
39	T	A	-2.2323
40	E	A	-3.2172
41	G	A	-1.4290
42	L	A	-0.3929
43	H	A	0.0000
44	G	A	0.0000
45	F	A	0.0000
46	H	A	0.0000
47	V	A	0.0000
48	H	A	0.0000
49	E	A	-0.6076
50	F	A	-0.3151
51	G	A	0.0000
52	D	A	-0.4525
53	N	A	-0.2752
54	T	A	-0.1598
55	A	A	-0.1574
56	G	A	-0.8346
57	C	A	-0.7151
58	T	A	-0.3575
59	S	A	-0.4496
60	A	A	0.0000
61	G	A	-0.5303
62	P	A	-0.6564
63	H	A	0.0000
64	F	A	0.0000
65	N	A	-0.9098
66	P	A	-0.5810
67	L	A	-0.2786
68	S	A	-1.2708
69	R	A	-3.2917
70	K	A	-3.5383
71	H	A	0.0000
72	G	A	0.0000
73	G	A	0.0000
74	P	A	-1.6855
75	K	A	-2.5957
76	D	A	-2.8698
77	E	A	-3.6976
78	E	A	-4.0355
79	R	A	0.0000
80	H	A	0.0000
81	V	A	0.0000
82	G	A	0.0000
83	D	A	0.0000
84	L	A	0.0000
85	G	A	0.0000
86	N	A	-0.1539
87	V	A	0.0000
88	T	A	-0.8789
89	A	A	0.0000
90	D	A	-4.0542
91	K	A	-3.9848
92	D	A	-3.6394
93	G	A	-3.0624
94	V	A	-2.4426
95	A	A	0.0000
96	D	A	-2.0742
97	V	A	0.0000
98	S	A	-0.8856
99	I	A	-0.9702
100	E	A	-2.0011
101	D	A	0.0000
102	S	A	-0.9162
103	V	A	-0.4649
104	I	A	0.0000
105	S	A	0.0000
106	L	A	0.0000
107	S	A	-1.1673
108	G	A	-1.7215
109	D	A	-2.0496
110	H	A	-1.2556
111	C	A	-0.9559
112	I	A	0.0000
113	T	A	-0.0680
114	G	A	0.0000
115	R	A	-0.1380
116	T	A	0.0000
117	L	A	0.0000
118	V	A	0.0000
119	V	A	0.0000
120	H	A	0.0000
121	E	A	-2.0420
122	K	A	-1.9679
123	A	A	-0.7717
124	D	A	0.0000
125	D	A	-1.2011
126	L	A	-1.0717
127	G	A	-2.5562
128	K	A	-2.3141
129	G	A	-2.4044
130	G	A	-2.3875
131	N	A	-3.2120
132	E	A	-3.5058
133	E	A	-3.2291
134	S	A	0.0000
135	T	A	-3.3478
136	K	A	-3.2923
137	T	A	-1.8091
138	G	A	0.0000
139	N	A	-2.0278
140	A	A	0.0000
141	G	A	-1.3960
142	S	A	-1.2579
143	R	A	-1.3031
144	L	A	-1.5087
145	A	A	0.0000
146	C	A	0.0000
147	G	A	0.0000
148	V	A	0.2162
149	I	A	0.0000
150	G	A	0.0000
151	I	A	-0.0815
152	A	A	-0.9187
153	Q	A	-1.3380
1	A	F	-1.5821
2	T	F	-1.5331
3	K	F	-1.6217
4	A	F	0.0000
5	V	F	0.0000
6	C	F	0.0000
7	V	F	-0.3471
8	L	F	0.0000
9	K	F	-2.5154
10	G	F	-2.4042
11	D	F	-2.7882
12	G	F	-2.2525
13	P	F	-2.4229
14	V	F	0.0000
15	Q	F	-2.6389
16	G	F	0.0000
17	I	F	-0.2537
18	I	F	0.0000
19	N	F	-0.6720
20	F	F	0.0000
21	E	F	-2.4147
22	Q	F	0.0000
23	K	F	-3.2851
24	E	F	-3.2922
25	S	F	-2.2079
26	N	F	-2.2915
27	G	F	-2.0244
28	P	F	-1.9048
29	V	F	0.0000
30	K	F	-2.5266
31	V	F	0.0000
32	W	F	-0.8131
33	G	F	-0.4295
34	S	F	-1.1624
35	I	F	0.0000
36	K	F	-2.9295
37	G	F	-2.4344
38	L	F	0.0000
39	T	F	-2.5815
40	E	F	-3.3569
41	G	F	-1.6186
42	L	F	-0.6271
43	H	F	0.0000
44	G	F	0.0000
45	F	F	0.0000
46	H	F	0.0000
47	V	F	0.0000
48	H	F	0.0000
49	E	F	-0.5544
50	F	F	-0.2872
51	G	F	0.0000
52	D	F	-0.4292
53	N	F	-0.2498
54	T	F	-0.1281
55	A	F	-0.1610
56	G	F	-0.5883
57	C	F	-0.4896
58	T	F	-0.3452
59	S	F	-0.4357
60	A	F	0.0000
61	G	F	-0.4543
62	P	F	-0.5401
63	H	F	0.0000
64	F	F	0.0000
65	N	F	-0.5564
66	P	F	-0.2162
67	L	F	0.2920
68	S	F	-0.4631
69	R	F	-1.8152
70	K	F	-2.7768
71	H	F	0.0000
72	G	F	0.0000
73	G	F	0.0000
74	P	F	-1.5469
75	K	F	-2.4145
76	D	F	-2.4323
77	E	F	-2.9921
78	E	F	-2.5593
79	R	F	0.0000
80	H	F	0.0000
81	V	F	0.0000
82	G	F	0.0000
83	D	F	0.0000
84	L	F	0.0000
85	G	F	0.0000
86	N	F	-0.2681
87	V	F	0.0000
88	T	F	-0.9031
89	A	F	0.0000
90	D	F	-4.1805
91	K	F	-4.0790
92	D	F	-3.8455
93	G	F	0.0000
94	V	F	-2.8673
95	A	F	0.0000
96	D	F	-2.2078
97	V	F	0.0000
98	S	F	-1.0673
99	I	F	-1.1688
100	E	F	-2.2674
101	D	F	0.0000
102	S	F	-0.9449
103	V	F	-0.3626
104	I	F	0.0000
105	S	F	-1.0623
106	L	F	0.0000
107	S	F	-1.1416
108	G	F	-1.5893
109	D	F	-1.9951
110	H	F	-1.0191
111	C	F	-0.7437
112	I	F	0.0000
113	T	F	-0.0015
114	G	F	0.0000
115	R	F	-0.1299
116	T	F	0.0000
117	L	F	0.0000
118	V	F	0.0000
119	V	F	0.0000
120	H	F	0.0000
121	E	F	-2.5788
122	K	F	-2.6085
123	A	F	-1.0932
124	D	F	0.0000
125	D	F	-1.3230
126	L	F	-1.2263
127	G	F	-2.6450
128	K	F	-2.3988
129	G	F	-2.5478
130	G	F	-2.5082
131	N	F	-3.4156
132	E	F	-3.8147
133	E	F	-3.8549
134	S	F	0.0000
135	T	F	-3.4476
136	K	F	-3.3733
137	T	F	-1.9970
138	G	F	0.0000
139	N	F	-2.3260
140	A	F	0.0000
141	G	F	-1.6679
142	S	F	-1.4575
143	R	F	-1.4241
144	L	F	-1.6889
145	A	F	0.0000
146	C	F	0.0000
147	G	F	0.0000
148	V	F	0.2180
149	I	F	0.0000
150	G	F	0.0000
151	I	F	-0.0245
152	A	F	-0.8625
153	Q	F	-1.3072