Project name: a5d1350832a3086

Chain sequence(s)	A: SSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHH
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.4266
• Maximal score value: 0.9678
• Average score: -1.0171
• Total score value: -207.4915

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
94	S	A	-0.3933
95	S	A	-0.3718
96	S	A	-0.2273
97	V	A	0.0855
98	P	A	-0.5225
99	S	A	-0.9169
100	Q	A	-1.2220
101	K	A	-1.7796
102	T	A	-0.9265
103	Y	A	-0.1100
104	Q	A	-1.2020
105	G	A	-0.8593
106	S	A	-0.6658
107	Y	A	-0.7911
108	G	A	-1.1557
109	F	A	0.0000
110	R	A	-1.1440
111	L	A	0.0000
112	G	A	-0.1208
113	F	A	0.0000
114	L	A	0.9678
115	H	A	-0.4190
116	S	A	-0.5101
117	G	A	-1.1692
118	T	A	-1.5339
119	A	A	-1.3059
120	K	A	-2.3486
121	S	A	-1.6224
122	V	A	-0.9582
123	T	A	-0.3698
124	C	A	0.0000
125	T	A	0.0000
126	Y	A	-0.3854
127	S	A	0.0000
128	P	A	-0.3866
129	A	A	-0.0048
130	L	A	0.0442
131	N	A	-0.4462
132	K	A	-0.7513
133	M	A	0.0000
134	F	A	0.0000
135	C	A	0.0000
136	Q	A	-0.1187
137	L	A	0.5388
138	A	A	0.2145
139	K	A	-0.1225
140	T	A	-0.5399
141	C	A	0.0000
142	P	A	-0.3305
143	V	A	0.0000
144	Q	A	-0.1459
145	L	A	0.0000
146	W	A	-0.5081
147	V	A	-0.8543
148	D	A	-1.8356
149	S	A	-0.8789
150	T	A	-0.4535
151	P	A	-0.5752
152	P	A	-0.6702
153	P	A	-0.9986
154	G	A	-1.2858
155	T	A	0.0000
156	R	A	-1.4822
157	V	A	0.0000
158	R	A	-0.8887
159	A	A	0.0000
160	M	A	-0.0856
161	A	A	0.1592
162	I	A	0.1489
163	Y	A	0.0000
164	K	A	-1.8073
165	Q	A	-1.7788
166	S	A	-1.5634
167	Q	A	-1.9297
168	H	A	-1.4852
169	M	A	-0.9818
170	T	A	-0.7016
171	E	A	-1.3575
172	V	A	0.6363
173	V	A	0.0000
174	R	A	-2.4397
175	R	A	-2.7447
176	C	A	0.0000
177	P	A	-2.0121
178	H	A	-2.1266
179	H	A	-2.0748
180	E	A	-2.5527
181	R	A	-2.6625
182	C	A	-1.2450
183	S	A	-2.0253
184	D	A	-2.7276
185	S	A	-1.7570
186	D	A	-2.1649
187	G	A	-1.1699
188	L	A	0.1780
189	A	A	0.0000
190	P	A	-0.8989
191	P	A	-1.8681
192	Q	A	-1.7815
193	H	A	0.0000
194	L	A	0.0000
195	I	A	0.0000
196	R	A	-0.8039
197	V	A	0.0000
198	E	A	-2.2233
199	G	A	-1.5804
200	N	A	-1.4956
201	L	A	-0.5638
202	R	A	-1.7017
203	V	A	-1.2929
204	E	A	-1.9056
205	Y	A	-1.0574
206	L	A	-1.4141
207	D	A	-2.5961
208	D	A	-3.2052
209	R	A	-3.1524
210	N	A	-2.5531
211	T	A	-1.4863
212	F	A	-0.6137
213	R	A	-1.3377
214	H	A	-0.7913
215	S	A	0.0000
216	V	A	0.0000
217	V	A	0.0000
218	V	A	0.0000
219	P	A	-1.3707
220	Y	A	-1.3952
221	E	A	-2.1935
222	P	A	-1.7870
223	P	A	-1.9173
224	E	A	-2.0164
225	V	A	0.1455
226	G	A	-0.6676
227	S	A	-1.2561
228	D	A	-2.0100
229	C	A	0.0000
230	T	A	-1.1337
231	T	A	-1.1566
232	I	A	0.0000
233	H	A	-1.4174
234	Y	A	0.0000
235	N	A	-0.6076
236	Y	A	0.0000
237	M	A	0.0308
238	C	A	0.0000
239	N	A	-0.3423
240	S	A	0.0000
241	S	A	-0.7612
242	C	A	-0.4240
243	M	A	-0.3840
244	G	A	-1.2011
245	G	A	-1.3103
246	M	A	0.0000
247	N	A	-1.7263
248	R	A	-2.4089
249	R	A	-2.2116
250	P	A	-1.2883
251	I	A	0.0000
252	L	A	0.0000
253	T	A	0.0000
254	I	A	0.0000
255	I	A	0.0000
256	T	A	0.0000
257	L	A	0.0000
258	E	A	-1.4233
259	D	A	-1.7890
260	S	A	-1.3045
261	S	A	-1.1311
262	G	A	-1.5396
263	N	A	-1.7411
264	L	A	-0.4943
265	L	A	-0.3459
266	G	A	0.0000
267	R	A	-0.5099
268	N	A	0.0000
269	S	A	-0.4361
270	F	A	0.0000
271	E	A	0.0000
272	V	A	0.0000
273	R	A	-0.7811
274	V	A	0.0000
275	C	A	-0.1560
276	A	A	-0.1453
277	C	A	-0.8868
278	P	A	0.0000
279	G	A	0.0000
280	R	A	-3.2390
281	D	A	-2.4490
282	R	A	-2.6998
283	R	A	-3.6146
284	T	A	-3.0309
285	E	A	-2.9004
286	E	A	-3.3093
287	E	A	-4.3995
288	N	A	-3.7429
289	L	A	-3.0468
290	R	A	-4.0984
291	K	A	-4.4266
292	K	A	-3.9495
293	G	A	-3.0663
294	E	A	-3.1951
295	P	A	-1.9135
296	H	A	-2.1282
297	H	A	-1.7348