Project name: 4g5z:H

Chain sequence(s)	H: QVQLVESGGGVVQPGRSLRLSCAASGFTFSVYGMNWVRQAPAKGLEWVAIIWYDGDNQYYADSVKGRFTISRDNSKNTLYLQMNGLRAEDTAVYYCARDLRTGPFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVAP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9225
• Maximal score value: 2.3195
• Average score: -0.5512
• Total score value: -120.167

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.4782
2	V	H	-0.8221
3	Q	H	-0.9922
4	L	H	0.0000
5	V	H	0.3498
6	E	H	0.0000
7	S	H	-0.3902
8	G	H	-0.6810
9	G	H	0.0018
10	G	H	0.5967
11	V	H	0.7972
12	V	H	0.0000
13	Q	H	-1.7135
14	P	H	-2.0032
15	G	H	-2.1935
16	R	H	-2.7752
17	S	H	-2.0562
18	L	H	-1.5620
19	R	H	-2.2946
20	L	H	0.0000
21	S	H	-0.5692
22	C	H	0.0000
23	A	H	-0.3564
24	A	H	0.0000
25	S	H	-0.8631
26	G	H	-1.0333
27	F	H	-0.1211
28	T	H	0.3506
29	F	H	0.0000
30	S	H	0.4774
31	V	H	1.8217
32	Y	H	1.1055
33	G	H	0.2775
34	M	H	0.0000
35	N	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.3887
40	A	H	0.0000
41	P	H	-0.7871
42	A	H	-1.0529
43	K	H	-1.8454
44	G	H	-0.8113
45	L	H	0.6115
46	E	H	-0.1473
47	W	H	0.1158
48	V	H	0.0000
49	A	H	0.0000
50	I	H	0.0000
51	I	H	0.0000
52	W	H	-0.4024
53	Y	H	0.3922
54	D	H	-1.8055
55	G	H	-2.1334
56	D	H	-2.8846
57	N	H	-2.2551
58	Q	H	-1.0219
59	Y	H	0.2819
60	Y	H	0.0000
61	A	H	-1.1323
62	D	H	-2.2846
63	S	H	-1.7479
64	V	H	0.0000
65	K	H	-2.4784
66	G	H	-1.8468
67	R	H	-1.5512
68	F	H	0.0000
69	T	H	-0.9986
70	I	H	0.0000
71	S	H	-1.0977
72	R	H	-1.3319
73	D	H	-1.9949
74	N	H	-1.6301
75	S	H	-1.6568
76	K	H	-2.5065
77	N	H	-1.9887
78	T	H	-1.2258
79	L	H	0.0000
80	Y	H	-0.6939
81	L	H	0.0000
82	Q	H	-1.7118
83	M	H	0.0000
84	N	H	-1.9870
85	G	H	-1.8045
86	L	H	0.0000
87	R	H	-2.5568
88	A	H	-1.6923
89	E	H	-2.2729
90	D	H	0.0000
91	T	H	-0.5025
92	A	H	0.0000
93	V	H	0.6660
94	Y	H	0.0000
95	Y	H	0.4208
96	C	H	0.0000
97	A	H	0.0000
98	R	H	0.0000
99	D	H	0.0000
100	L	H	-0.4124
101	R	H	-1.3902
102	T	H	-0.9438
103	G	H	-1.0601
104	P	H	-0.5450
105	F	H	0.1296
106	D	H	0.0869
107	Y	H	0.6757
108	W	H	0.5756
109	G	H	-0.0660
110	Q	H	-0.9743
111	G	H	-0.0150
112	T	H	0.0000
113	L	H	1.5401
114	V	H	0.0000
115	T	H	0.0478
116	V	H	0.0000
117	S	H	-0.7137
118	S	H	-0.6801
119	A	H	-0.4191
120	S	H	-0.5391
121	T	H	-0.7103
122	K	H	-1.3927
123	G	H	-1.6143
124	P	H	0.0000
125	S	H	-0.2155
126	V	H	0.0000
127	F	H	0.9739
128	P	H	0.4186
129	L	H	0.8505
130	A	H	-0.0748
131	P	H	0.0000
132	S	H	-0.7234
133	S	H	-1.1473
134	K	H	-1.8743
135	S	H	-0.9873
136	T	H	-1.0539
137	S	H	-0.9500
138	G	H	-0.8503
139	G	H	-0.9070
140	T	H	-0.6921
141	A	H	0.0000
142	A	H	-0.1765
143	L	H	0.0000
144	G	H	0.0000
145	C	H	0.0000
146	L	H	0.8512
147	V	H	0.0000
148	K	H	-0.2239
149	D	H	-0.7588
150	Y	H	0.0000
151	F	H	0.0000
152	P	H	-0.9008
153	E	H	-1.4036
154	P	H	-1.3859
155	V	H	-1.0584
156	T	H	-0.8335
157	V	H	-0.2863
158	S	H	-0.4212
159	W	H	0.0000
160	N	H	-0.8049
161	S	H	-0.6656
162	G	H	-0.5795
163	A	H	-0.2543
164	L	H	-0.0090
165	T	H	-0.2736
166	S	H	-0.3279
167	G	H	-0.4440
168	V	H	0.0419
169	H	H	-0.5482
170	T	H	0.0716
171	F	H	0.7406
172	P	H	0.5539
173	A	H	0.9915
174	V	H	2.3195
175	L	H	1.7305
176	Q	H	0.5397
177	S	H	0.0251
178	S	H	-0.2556
179	G	H	0.1164
180	L	H	-0.0386
181	Y	H	0.0000
182	S	H	0.0000
183	L	H	0.8483
184	S	H	0.6944
185	S	H	0.0000
186	V	H	0.3813
187	V	H	0.0000
188	T	H	-0.2532
189	V	H	0.0000
190	P	H	-0.6984
191	S	H	-0.5659
192	S	H	-0.5688
193	S	H	0.0000
194	L	H	-0.5192
195	G	H	-0.8046
196	T	H	-0.8393
197	Q	H	-1.3653
198	T	H	-0.9904
199	Y	H	0.0000
200	I	H	-1.0618
201	C	H	0.0000
202	N	H	-1.5562
203	V	H	0.0000
204	N	H	-2.3110
205	H	H	0.0000
206	K	H	-2.9225
207	P	H	-1.8327
208	S	H	-1.8771
209	N	H	-2.6324
210	T	H	-2.1981
211	K	H	-2.7386
212	V	H	-1.4774
213	D	H	-2.4508
214	K	H	-1.8199
215	R	H	-2.2730
216	V	H	0.0000
217	A	H	-0.7107
218	P	H	-0.4341