Project name: 5icz;A

Chain sequence(s)	A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGA
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.9348
• Maximal score value: 2.2141
• Average score: -0.8225
• Total score value: -175.1935

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	A	-1.4556
2	I	A	0.0000
3	L	A	0.7797
4	L	A	0.0000
5	T	A	-0.3141
6	Q	A	-0.0662
7	S	A	0.2113
8	P	A	1.0396
9	V	A	2.2141
10	I	A	1.9145
11	L	A	0.8639
12	S	A	-0.3292
13	V	A	0.0000
14	S	A	-1.9723
15	P	A	-2.0963
16	G	A	-2.2867
17	E	A	-3.1561
18	R	A	-3.2809
19	V	A	0.0000
20	S	A	-0.7633
21	F	A	0.0000
22	S	A	-0.8504
23	C	A	0.0000
24	R	A	-2.6440
25	A	A	-1.4339
26	S	A	-1.0506
27	Q	A	-1.6149
28	S	A	-1.6545
29	I	A	0.0000
30	G	A	-1.1445
31	T	A	-0.8410
32	N	A	-1.1205
33	I	A	0.0000
34	H	A	0.0000
35	W	A	0.0000
36	Y	A	0.0223
37	Q	A	0.0000
38	Q	A	-1.4364
39	R	A	-2.1401
40	T	A	-1.8846
41	N	A	-1.7852
42	G	A	-1.5343
43	S	A	-1.0538
44	P	A	-0.9556
45	R	A	-0.6854
46	L	A	-0.0242
47	L	A	0.0000
48	I	A	0.0000
49	K	A	-0.7191
50	Y	A	-0.1730
51	A	A	0.0000
52	S	A	-1.1427
53	E	A	-1.8900
54	S	A	-1.0794
55	I	A	-0.4885
56	S	A	-0.2282
57	G	A	-0.3961
58	I	A	-0.1307
59	P	A	-0.2880
60	S	A	-0.5473
61	R	A	-1.1302
62	F	A	0.0000
63	S	A	-0.8898
64	G	A	0.0000
65	S	A	-0.8244
66	G	A	-1.1592
67	S	A	-1.1966
68	G	A	-1.4706
69	T	A	-2.1163
70	D	A	-2.9071
71	F	A	0.0000
72	T	A	-0.9402
73	L	A	0.0000
74	S	A	-0.9099
75	I	A	0.0000
76	N	A	-2.6152
77	S	A	-2.4275
78	V	A	0.0000
79	E	A	-2.3723
80	S	A	-2.3402
81	E	A	-2.1973
82	D	A	0.0000
83	I	A	0.0000
84	A	A	0.0000
85	D	A	-0.5871
86	Y	A	0.0000
87	Y	A	0.2690
88	C	A	0.0000
89	Q	A	0.1452
90	Q	A	0.0000
91	N	A	-1.6310
92	N	A	-2.1766
93	N	A	-1.6153
94	W	A	-0.1411
95	P	A	-0.4027
96	T	A	-0.5678
97	T	A	0.2637
98	F	A	1.5392
99	G	A	0.6868
100	A	A	0.6780
101	G	A	0.5310
102	T	A	0.0000
103	K	A	0.4226
104	L	A	0.0000
105	E	A	-0.9720
106	L	A	0.0000
107	K	A	-1.7871
108	R	A	-1.1852
109	T	A	-0.0696
110	V	A	0.3946
111	A	A	0.1091
112	A	A	-0.1785
113	P	A	0.0000
114	S	A	-0.0289
115	V	A	0.4631
116	F	A	1.3949
117	I	A	1.3225
118	F	A	1.4600
119	P	A	-0.0472
120	P	A	-0.7574
121	S	A	-1.7964
122	D	A	-3.1978
123	E	A	-3.3503
124	Q	A	-2.4958
125	L	A	-2.6145
126	K	A	-2.9775
127	S	A	-1.8748
128	G	A	-1.3898
129	T	A	-1.0811
130	A	A	0.0000
131	S	A	0.0073
132	V	A	0.0000
133	V	A	0.7129
134	C	A	0.0000
135	L	A	0.6141
136	L	A	0.0000
137	N	A	-0.5155
138	N	A	-1.3343
139	F	A	0.0000
140	Y	A	-1.1971
141	P	A	-1.7303
142	R	A	-2.9164
143	E	A	-3.2434
144	A	A	-2.3284
145	K	A	-2.1530
146	V	A	-1.2432
147	Q	A	-0.7714
148	W	A	0.0000
149	K	A	-0.7331
150	V	A	0.0000
151	D	A	-1.9572
152	N	A	-1.4708
153	A	A	-0.3767
154	L	A	0.6240
155	Q	A	-0.1517
156	S	A	-0.4204
157	G	A	-1.0200
158	N	A	-0.9948
159	S	A	-1.4311
160	Q	A	-2.2789
161	E	A	-2.3275
162	S	A	-1.3412
163	V	A	-0.7576
164	T	A	-1.1755
165	E	A	-2.3097
166	Q	A	0.0000
167	D	A	-2.4571
168	S	A	-2.5220
169	K	A	-2.8475
170	D	A	-2.2181
171	S	A	0.0000
172	T	A	0.0000
173	Y	A	0.0000
174	S	A	-0.9927
175	L	A	0.0000
176	S	A	-0.4257
177	S	A	0.0000
178	T	A	-0.5876
179	L	A	0.0000
180	T	A	-0.4156
181	L	A	-0.8344
182	S	A	-1.4991
183	K	A	-2.5817
184	A	A	-2.2665
185	D	A	-2.9350
186	Y	A	0.0000
187	E	A	-3.9348
188	K	A	-3.8217
189	H	A	-3.2362
190	K	A	-3.0849
191	V	A	-1.4388
192	Y	A	0.0000
193	A	A	-0.9689
194	C	A	0.0000
195	E	A	-0.9742
196	V	A	0.0000
197	T	A	-1.2672
198	H	A	0.0000
199	Q	A	-1.5619
200	G	A	-0.4030
201	L	A	-0.2426
202	S	A	-0.4661
203	S	A	-0.4528
204	P	A	-0.5915
205	V	A	0.0106
206	T	A	-0.3054
207	K	A	-0.1999
208	S	A	-0.3224
209	F	A	-0.5373
210	N	A	-1.6432
211	R	A	-2.3849
212	G	A	-1.4561
213	A	A	-0.7516