Project name: 5i2i:A

Chain sequence(s)	A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGA
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.8152
• Maximal score value: 1.8065
• Average score: -0.8558
• Total score value: -182.2906

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	A	-1.4756
2	I	A	0.0000
3	L	A	0.7736
4	L	A	0.0000
5	T	A	-0.2600
6	Q	A	0.0548
7	S	A	0.0213
8	P	A	0.7628
9	V	A	1.8065
10	I	A	1.1143
11	L	A	0.3533
12	S	A	-0.5982
13	V	A	0.0000
14	S	A	-1.9164
15	P	A	-1.9644
16	G	A	-2.2720
17	E	A	-3.1557
18	R	A	-3.3636
19	V	A	0.0000
20	S	A	-0.7562
21	F	A	0.0000
22	S	A	-1.0163
23	C	A	0.0000
24	R	A	-2.5430
25	A	A	-1.3461
26	S	A	-1.0536
27	Q	A	-1.7182
28	S	A	-1.6304
29	I	A	0.0000
30	G	A	-1.0773
31	T	A	-0.8004
32	N	A	-1.0732
33	I	A	0.0000
34	H	A	0.0000
35	W	A	0.0000
36	Y	A	-0.0697
37	Q	A	0.0000
38	Q	A	-1.8613
39	R	A	-3.0692
40	T	A	-2.2729
41	N	A	-2.1657
42	G	A	-1.7802
43	S	A	-1.2316
44	P	A	-1.1771
45	R	A	-0.9648
46	L	A	-0.2118
47	L	A	0.0000
48	I	A	0.0000
49	K	A	-1.1632
50	Y	A	-0.6572
51	A	A	0.0000
52	S	A	-1.3078
53	E	A	-2.1191
54	S	A	-1.1976
55	I	A	-0.5398
56	S	A	-0.4147
57	G	A	-0.3851
58	I	A	-0.1445
59	P	A	-0.2893
60	S	A	-0.5660
61	R	A	-1.1417
62	F	A	0.0000
63	S	A	-0.8889
64	G	A	-0.7908
65	S	A	-0.8305
66	G	A	-1.0813
67	S	A	-1.0765
68	G	A	-1.3283
69	T	A	-1.9375
70	D	A	-2.5777
71	F	A	0.0000
72	T	A	-0.9071
73	L	A	0.0000
74	S	A	-0.9135
75	I	A	0.0000
76	N	A	-2.4774
77	S	A	-2.3896
78	V	A	0.0000
79	E	A	-2.7690
80	S	A	0.0000
81	E	A	-3.0101
82	D	A	0.0000
83	I	A	-2.1197
84	A	A	0.0000
85	D	A	-0.9839
86	Y	A	0.0000
87	Y	A	0.1901
88	C	A	0.0000
89	Q	A	0.1461
90	Q	A	0.0000
91	N	A	-1.5128
92	N	A	-2.0113
93	N	A	-1.7413
94	W	A	-0.1718
95	P	A	-0.4313
96	T	A	-0.5693
97	T	A	0.2690
98	F	A	1.5323
99	G	A	0.6803
100	A	A	0.6040
101	G	A	0.3278
102	T	A	0.0000
103	K	A	-0.5026
104	L	A	0.0000
105	E	A	-1.3972
106	L	A	0.0000
107	K	A	-1.6025
108	R	A	-1.1086
109	T	A	-0.0362
110	V	A	0.4628
111	A	A	-0.0673
112	A	A	-0.1793
113	P	A	0.0000
114	S	A	-0.1560
115	V	A	0.0000
116	F	A	1.4134
117	I	A	1.3970
118	F	A	1.6045
119	P	A	0.0494
120	P	A	-0.6860
121	S	A	-1.7778
122	D	A	-3.2304
123	E	A	-3.4184
124	Q	A	-2.4719
125	L	A	-2.5527
126	K	A	-2.9826
127	S	A	-1.8623
128	G	A	-1.2514
129	T	A	-1.1098
130	A	A	0.0000
131	S	A	0.0636
132	V	A	0.0000
133	V	A	0.7823
134	C	A	0.0000
135	L	A	0.5626
136	L	A	0.0000
137	N	A	-0.6952
138	N	A	-1.3584
139	F	A	0.0000
140	Y	A	-1.1423
141	P	A	-1.6927
142	R	A	-2.9174
143	E	A	-3.2444
144	A	A	-2.3049
145	K	A	-2.2393
146	V	A	-1.0112
147	Q	A	-0.5826
148	W	A	0.0000
149	K	A	-0.5698
150	V	A	0.0000
151	D	A	-1.8553
152	N	A	-1.3107
153	A	A	-0.2393
154	L	A	0.7451
155	Q	A	-0.1153
156	S	A	-0.3932
157	G	A	-1.0415
158	N	A	-1.0231
159	S	A	-1.4394
160	Q	A	-2.3093
161	E	A	-2.4888
162	S	A	-1.3308
163	V	A	-0.8081
164	T	A	-1.2316
165	E	A	-2.6402
166	Q	A	0.0000
167	D	A	-2.5144
168	S	A	-2.8757
169	K	A	-2.9017
170	D	A	-2.0471
171	S	A	0.0000
172	T	A	0.0000
173	Y	A	0.0000
174	S	A	-1.0730
175	L	A	0.0000
176	S	A	-0.4831
177	S	A	0.0000
178	T	A	-0.5787
179	L	A	0.0000
180	T	A	-0.5337
181	L	A	-0.7476
182	S	A	-1.2549
183	K	A	-2.0980
184	A	A	-2.0177
185	D	A	-2.7390
186	Y	A	0.0000
187	E	A	-3.7766
188	K	A	-3.8152
189	H	A	-3.1319
190	K	A	-3.0081
191	V	A	-1.3471
192	Y	A	0.0000
193	A	A	0.0000
194	C	A	0.0000
195	E	A	-0.8664
196	V	A	0.0000
197	T	A	-1.1978
198	H	A	0.0000
199	Q	A	-1.5470
200	G	A	-0.3692
201	L	A	-0.1830
202	S	A	-0.4406
203	S	A	-0.4398
204	P	A	-0.6151
205	V	A	-0.1456
206	T	A	-0.3716
207	K	A	-0.3103
208	S	A	-0.2839
209	F	A	-0.5205
210	N	A	-1.5990
211	R	A	-2.3321
212	G	A	-1.4317
213	A	A	-0.7621