Project name: 5sx4:J

Chain sequence(s)	J: QVQLQESGPGLVKPSETLSLTCTVSGGSVSSGDYYWTWIRQSPGKGLEWIGHIYYSGNTNYNPSLKSRLTISIDTSKTQFSLKLSSVTAADTAIYYCVRDRVTGAFDIWGQGTMVTVSSASTKGPSVFPLAPCTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPQTYTCNVDHKPSNTKVDKTVE
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.7252
• Maximal score value: 2.46
• Average score: -0.464
• Total score value: -95.115

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	J	-1.5737
2	V	J	-1.2325
3	Q	J	-1.8439
4	L	J	0.0000
5	Q	J	-1.4470
6	E	J	0.0000
7	S	J	-0.6067
8	G	J	-0.6028
9	P	J	-0.5616
10	G	J	-0.3629
11	L	J	-0.3882
12	V	J	0.0000
13	K	J	-2.4031
14	P	J	-1.7351
15	S	J	-1.7094
16	E	J	-2.5820
17	T	J	-1.7253
18	L	J	0.0000
19	S	J	-0.9550
20	L	J	0.0000
21	T	J	-0.6163
22	C	J	0.0000
23	T	J	-1.0799
24	V	J	0.0000
25	S	J	-1.4541
26	G	J	-1.2791
27	G	J	-0.9960
28	S	J	-0.7510
29	V	J	0.0000
30	S	J	-0.2996
31	S	J	-0.6259
32	G	J	-0.6558
33	D	J	-1.5111
34	Y	J	-0.4631
35	Y	J	0.0035
36	W	J	0.0000
37	T	J	0.0000
38	W	J	0.0000
39	I	J	0.0000
40	R	J	0.0000
41	Q	J	-0.0198
42	S	J	-0.4373
43	P	J	-0.7373
44	G	J	-1.1346
45	K	J	-1.4151
46	G	J	-0.3797
47	L	J	0.9296
48	E	J	0.1934
49	W	J	0.4709
50	I	J	0.0000
51	G	J	0.0000
52	H	J	-0.4305
53	I	J	0.0000
54	Y	J	-0.0438
55	Y	J	0.3857
56	S	J	-0.2532
57	G	J	-0.7268
58	N	J	-1.5543
59	T	J	-1.1865
60	N	J	-1.7194
61	Y	J	-1.1973
62	N	J	-1.0904
63	P	J	-1.2848
64	S	J	-0.9130
65	L	J	0.0000
66	K	J	-2.2661
67	S	J	-1.3619
68	R	J	-1.3754
69	L	J	0.0000
70	T	J	-1.0429
71	I	J	0.0000
72	S	J	-0.4524
73	I	J	-0.2312
74	D	J	-1.0410
75	T	J	-0.8933
76	S	J	-1.3288
77	K	J	-2.0884
78	T	J	-1.4037
79	Q	J	-1.1882
80	F	J	0.0000
81	S	J	-0.5423
82	L	J	0.0000
83	K	J	-1.3835
84	L	J	0.0000
85	S	J	-1.3137
86	S	J	-1.3808
87	V	J	0.0000
88	T	J	-0.7143
89	A	J	-0.2395
90	A	J	-0.2030
91	D	J	0.0000
92	T	J	0.1236
93	A	J	0.0000
94	I	J	0.7642
95	Y	J	0.0000
96	Y	J	0.1963
97	C	J	0.0000
98	V	J	0.0000
99	R	J	0.0000
100	D	J	-0.2106
101	R	J	-0.7804
102	V	J	0.1447
103	T	J	-0.2210
104	G	J	-0.2625
105	A	J	-0.0342
106	F	J	0.5070
107	D	J	-0.2422
108	I	J	-0.1976
109	W	J	-0.0175
110	G	J	-0.8647
111	Q	J	-1.3445
112	G	J	-0.4633
113	T	J	-0.1619
114	M	J	0.3218
115	V	J	0.0000
116	T	J	0.0000
117	V	J	0.0000
118	S	J	-0.7402
119	S	J	-0.8857
120	A	J	-0.5895
121	S	J	-0.7025
122	T	J	-0.7241
123	K	J	-1.4111
124	G	J	-1.6257
125	P	J	-0.6769
126	S	J	-0.1019
127	V	J	0.0000
128	F	J	1.3851
129	P	J	0.5103
130	L	J	0.6458
131	A	J	0.0380
132	P	J	-0.0025
133	C	J	0.6569
141	T	J	-0.1062
142	A	J	-0.0055
143	A	J	0.2101
144	L	J	0.1768
145	G	J	0.0000
146	C	J	0.0000
147	L	J	0.7582
148	V	J	0.0000
149	K	J	-0.2595
150	D	J	-0.8041
151	Y	J	0.0000
152	F	J	0.0000
153	P	J	0.0000
154	E	J	-0.3382
155	P	J	-0.5852
156	V	J	-0.5788
157	T	J	-0.5482
158	V	J	-0.3938
159	S	J	-0.5808
160	W	J	0.0000
161	N	J	-0.8575
162	S	J	-0.8290
163	G	J	-0.6208
164	A	J	-0.2813
165	L	J	-0.0432
166	T	J	-0.2849
167	S	J	-0.2998
168	G	J	-0.3486
169	V	J	0.1046
170	H	J	-0.3970
171	T	J	0.2097
172	F	J	1.0854
173	P	J	0.7640
174	A	J	1.2874
175	V	J	2.4600
176	L	J	1.9942
177	Q	J	0.5999
178	S	J	0.0486
179	S	J	-0.2868
180	G	J	0.0874
181	L	J	0.1821
182	Y	J	0.7194
183	S	J	0.0000
184	L	J	0.0000
185	S	J	0.7075
186	S	J	0.0000
187	V	J	0.5362
188	V	J	0.0000
189	T	J	-0.0711
190	V	J	0.0657
191	P	J	-0.1958
198	Q	J	-1.3846
199	T	J	-0.9536
200	Y	J	-0.7886
201	T	J	-1.0753
202	C	J	0.0000
203	N	J	-1.4072
204	V	J	0.0000
205	D	J	-1.8214
206	H	J	0.0000
207	K	J	-2.7252
208	P	J	-1.6044
209	S	J	-1.9050
210	N	J	-2.5928
211	T	J	-2.0697
212	K	J	-2.6476
213	V	J	-1.4624
214	D	J	-2.2971
215	K	J	-1.3192
216	T	J	-0.9749
217	V	J	0.0000
218	E	J	-1.9481