Project name: 5jq6:H

Chain sequence(s)	H: QVQLKESGPGLVKPSQTLSITCTISGFSLSRYSVHWVRQPPGKGLEWLGMIWGGGNTDYNSALKSRLSISKDNSKNQVFLKMNSLTAADTAVYYCARKGEFYYGYDGFVYWGQGTLVTVSSASTKGPSVFPLAPALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSYICNVNHKPSNTKVDKRAE
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.7493
• Maximal score value: 2.596
• Average score: -0.3879
• Total score value: -79.1266

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.5378
2	V	H	-0.9629
3	Q	H	-1.7142
4	L	H	0.0000
5	K	H	-1.6077
6	E	H	0.0000
7	S	H	-0.5905
8	G	H	-0.3205
9	P	H	-0.0480
10	G	H	0.2395
11	L	H	0.6014
12	V	H	0.0000
13	K	H	-1.6172
14	P	H	-1.2904
15	S	H	-1.3397
16	Q	H	-1.6735
17	T	H	-1.3600
18	L	H	0.0000
19	S	H	-0.7303
20	I	H	0.0000
21	T	H	-0.4239
22	C	H	0.0000
23	T	H	-1.1560
24	I	H	0.0000
25	S	H	-1.1552
26	G	H	-1.1167
27	F	H	-0.7401
28	S	H	-0.8785
29	L	H	0.0000
30	S	H	-1.3834
31	R	H	-1.8214
32	Y	H	-0.7592
33	S	H	0.0000
34	V	H	0.0000
35	H	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.2942
40	P	H	-0.6090
41	P	H	-0.9396
42	G	H	-1.4316
43	K	H	-2.0726
44	G	H	-0.9296
45	L	H	0.5791
46	E	H	-0.1207
47	W	H	0.3594
48	L	H	0.0000
49	G	H	0.0000
50	M	H	-0.2035
51	I	H	0.0000
52	W	H	-0.3398
53	G	H	-1.0112
54	G	H	-1.1382
55	G	H	-1.0774
56	N	H	-1.4730
57	T	H	-0.9723
58	D	H	-1.2828
59	Y	H	-0.9541
60	N	H	-0.9173
61	S	H	-0.9588
62	A	H	-0.6311
63	L	H	0.0000
64	K	H	-2.1221
65	S	H	-1.3720
66	R	H	-1.4306
67	L	H	0.0000
68	S	H	-1.0230
69	I	H	0.0000
70	S	H	-0.6572
71	K	H	-1.1150
72	D	H	-1.9573
73	N	H	-2.3737
74	S	H	-1.8597
75	K	H	-2.6097
76	N	H	-2.0842
77	Q	H	-1.6122
78	V	H	0.0000
79	F	H	-0.1931
80	L	H	0.0000
81	K	H	-1.0607
82	M	H	0.0000
83	N	H	-1.5413
84	S	H	-1.1010
85	L	H	0.0000
86	T	H	-0.4333
87	A	H	-0.1598
88	A	H	0.0546
89	D	H	0.0000
90	T	H	0.3175
91	A	H	0.0000
92	V	H	0.8678
93	Y	H	0.0000
94	Y	H	0.2646
95	C	H	0.0000
96	A	H	0.0000
97	R	H	0.0000
98	K	H	0.6447
99	G	H	0.0000
100	E	H	1.2054
101	F	H	2.5960
102	Y	H	2.5645
103	Y	H	1.9488
104	G	H	1.2734
105	Y	H	1.4859
106	D	H	0.2647
107	G	H	0.5484
108	F	H	1.4370
109	V	H	1.2738
110	Y	H	0.8348
111	W	H	0.3960
112	G	H	0.0000
113	Q	H	-1.2274
114	G	H	0.0000
115	T	H	0.1832
116	L	H	1.2602
117	V	H	0.0000
118	T	H	0.3522
119	V	H	0.0000
120	S	H	-0.4560
121	S	H	-0.6516
122	A	H	-0.4454
123	S	H	-0.4886
124	T	H	-0.7442
125	K	H	-1.1453
126	G	H	-1.3339
127	P	H	0.0000
128	S	H	-0.0845
129	V	H	0.0000
130	F	H	0.6822
131	P	H	0.0365
132	L	H	0.5162
133	A	H	-0.3967
134	P	H	-0.4523
145	A	H	0.2558
146	L	H	0.3138
147	G	H	0.0000
148	C	H	0.0000
149	L	H	0.6412
150	V	H	0.0000
151	K	H	-0.2641
152	D	H	-0.4037
153	Y	H	0.0000
154	F	H	0.0000
155	P	H	-1.0374
156	E	H	-1.4442
157	P	H	-1.2723
158	V	H	-0.6567
159	T	H	-0.6538
160	V	H	-0.2545
161	S	H	-0.4782
162	W	H	0.0000
163	N	H	-0.5850
164	S	H	-0.7899
165	G	H	-0.6404
166	A	H	-0.2393
167	L	H	0.3166
168	T	H	-0.1771
169	S	H	-0.1864
170	G	H	-0.2584
171	V	H	0.3133
172	H	H	-0.3968
173	T	H	0.2069
174	F	H	0.9983
175	P	H	0.7176
176	A	H	1.0806
177	V	H	2.3918
178	L	H	1.9425
179	Q	H	0.6805
180	S	H	0.1058
181	S	H	-0.1840
182	G	H	0.1935
183	L	H	0.1095
184	Y	H	0.0000
185	S	H	0.0000
186	L	H	0.0000
187	S	H	0.6020
188	S	H	0.0000
189	V	H	0.5184
190	V	H	0.0000
191	T	H	0.0738
192	V	H	0.4533
193	P	H	-0.1141
195	S	H	-0.3435
196	S	H	-0.3703
202	Y	H	0.3741
203	I	H	-0.7451
204	C	H	0.0000
205	N	H	-1.7602
206	V	H	0.0000
207	N	H	-1.9401
208	H	H	0.0000
209	K	H	-2.7493
210	P	H	-1.7785
211	S	H	-1.7985
212	N	H	-2.4528
213	T	H	-2.0595
214	K	H	-2.7358
215	V	H	-1.7202
216	D	H	-2.6641
217	K	H	-1.9023
218	R	H	-2.2866
219	A	H	-1.1676
220	E	H	-1.9773