Project name: 5f88:A
Status: done
submitted: 2019-03-20 20:26:09, status changed: 2019-03-20 20:39:03
Settings
|
Chain sequence(s)
|
A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGA
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.8461
-
Maximal score value
-
2.2103
-
Average score
-
-0.8235
-
Total score value
-
-175.4033
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-1.3463 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
L |
A |
0.7952 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
T |
A |
-0.0837 |
|
| 6 |
Q |
A |
0.0000 |
|
| 7 |
S |
A |
0.2701 |
|
| 8 |
P |
A |
1.0038 |
|
| 9 |
V |
A |
2.2103 |
|
| 10 |
I |
A |
1.7237 |
|
| 11 |
L |
A |
0.7046 |
|
| 12 |
S |
A |
-0.4859 |
|
| 13 |
V |
A |
0.0000 |
|
| 14 |
S |
A |
-1.9645 |
|
| 15 |
P |
A |
-2.0168 |
|
| 16 |
G |
A |
-2.2141 |
|
| 17 |
E |
A |
-2.9691 |
|
| 18 |
R |
A |
-3.1338 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
S |
A |
-0.7776 |
|
| 21 |
F |
A |
0.0000 |
|
| 22 |
S |
A |
-0.5916 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.0841 |
|
| 25 |
A |
A |
0.0000 |
|
| 26 |
S |
A |
-0.9600 |
|
| 27 |
Q |
A |
-1.4218 |
|
| 28 |
S |
A |
-1.5574 |
|
| 29 |
I |
A |
0.0000 |
|
| 30 |
G |
A |
-1.1571 |
|
| 31 |
T |
A |
-0.8857 |
|
| 32 |
N |
A |
-1.2470 |
|
| 33 |
I |
A |
0.0000 |
|
| 34 |
H |
A |
0.0000 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.0644 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-1.2928 |
|
| 39 |
R |
A |
-1.8490 |
|
| 40 |
T |
A |
-1.6709 |
|
| 41 |
N |
A |
-1.6638 |
|
| 42 |
G |
A |
-1.4215 |
|
| 43 |
S |
A |
-1.0480 |
|
| 44 |
P |
A |
-1.0260 |
|
| 45 |
R |
A |
-0.9073 |
|
| 46 |
L |
A |
-0.1092 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
K |
A |
-0.7653 |
|
| 50 |
Y |
A |
-0.5892 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
-1.2335 |
|
| 53 |
E |
A |
-1.9477 |
|
| 54 |
S |
A |
-1.0678 |
|
| 55 |
I |
A |
-0.3636 |
|
| 56 |
S |
A |
-0.2096 |
|
| 57 |
G |
A |
-0.3740 |
|
| 58 |
I |
A |
-0.1339 |
|
| 59 |
P |
A |
-0.2759 |
|
| 60 |
S |
A |
-0.5410 |
|
| 61 |
R |
A |
-1.1351 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
-0.8523 |
|
| 64 |
G |
A |
-0.7184 |
|
| 65 |
S |
A |
-0.7764 |
|
| 66 |
G |
A |
-0.9373 |
|
| 67 |
S |
A |
-0.9883 |
|
| 68 |
G |
A |
-1.2249 |
|
| 69 |
T |
A |
-1.6478 |
|
| 70 |
D |
A |
-1.9487 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.7397 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
S |
A |
-0.9061 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
N |
A |
-2.4481 |
|
| 77 |
S |
A |
-2.3915 |
|
| 78 |
V |
A |
0.0000 |
|
| 79 |
E |
A |
-2.9247 |
|
| 80 |
S |
A |
-2.8317 |
|
| 81 |
E |
A |
-2.9812 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
I |
A |
0.0000 |
|
| 84 |
A |
A |
0.0000 |
|
| 85 |
D |
A |
-0.7844 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
0.2410 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.0985 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
N |
A |
-1.6435 |
|
| 92 |
N |
A |
-2.1336 |
|
| 93 |
N |
A |
-1.5227 |
|
| 94 |
W |
A |
-0.0879 |
|
| 95 |
P |
A |
-0.2309 |
|
| 96 |
T |
A |
-0.5383 |
|
| 97 |
T |
A |
0.2696 |
|
| 98 |
F |
A |
1.5086 |
|
| 99 |
G |
A |
0.7357 |
|
| 100 |
A |
A |
0.6888 |
|
| 101 |
G |
A |
0.4935 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
0.2243 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
E |
A |
-1.1420 |
|
| 106 |
L |
A |
0.0000 |
|
| 107 |
K |
A |
-1.9669 |
|
| 108 |
R |
A |
-1.2181 |
|
| 109 |
T |
A |
-0.1586 |
|
| 110 |
V |
A |
0.2738 |
|
| 111 |
A |
A |
0.0522 |
|
| 112 |
A |
A |
-0.2459 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
-0.1619 |
|
| 115 |
V |
A |
0.0000 |
|
| 116 |
F |
A |
1.3532 |
|
| 117 |
I |
A |
1.2869 |
|
| 118 |
F |
A |
1.4514 |
|
| 119 |
P |
A |
-0.0784 |
|
| 120 |
P |
A |
0.0000 |
|
| 121 |
S |
A |
-1.7920 |
|
| 122 |
D |
A |
-3.2030 |
|
| 123 |
E |
A |
-3.4142 |
|
| 124 |
Q |
A |
-2.5118 |
|
| 125 |
L |
A |
-2.6096 |
|
| 126 |
K |
A |
-2.9977 |
|
| 127 |
S |
A |
-1.8875 |
|
| 128 |
G |
A |
-1.3967 |
|
| 129 |
T |
A |
-1.2050 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
0.0067 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.7087 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.4811 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.6967 |
|
| 138 |
N |
A |
-1.3140 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
-1.1515 |
|
| 141 |
P |
A |
-1.6939 |
|
| 142 |
R |
A |
-2.9207 |
|
| 143 |
E |
A |
-3.1537 |
|
| 144 |
A |
A |
-2.3072 |
|
| 145 |
K |
A |
-2.3921 |
|
| 146 |
V |
A |
-1.2993 |
|
| 147 |
Q |
A |
-0.9334 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.7394 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-2.0473 |
|
| 152 |
N |
A |
-1.5926 |
|
| 153 |
A |
A |
-0.2923 |
|
| 154 |
L |
A |
0.6815 |
|
| 155 |
Q |
A |
-0.2524 |
|
| 156 |
S |
A |
-0.4413 |
|
| 157 |
G |
A |
-1.0529 |
|
| 158 |
N |
A |
-1.0475 |
|
| 159 |
S |
A |
-1.4802 |
|
| 160 |
Q |
A |
-2.3260 |
|
| 161 |
E |
A |
-2.3499 |
|
| 162 |
S |
A |
-1.3446 |
|
| 163 |
V |
A |
-0.7690 |
|
| 164 |
T |
A |
-1.2539 |
|
| 165 |
E |
A |
-2.3074 |
|
| 166 |
Q |
A |
0.0000 |
|
| 167 |
D |
A |
-2.4509 |
|
| 168 |
S |
A |
-2.6908 |
|
| 169 |
K |
A |
-2.8488 |
|
| 170 |
D |
A |
-1.8204 |
|
| 171 |
S |
A |
0.0000 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
-1.4945 |
|
| 174 |
S |
A |
-1.0110 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.5103 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.6277 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.4285 |
|
| 181 |
L |
A |
-0.7672 |
|
| 182 |
S |
A |
-1.2016 |
|
| 183 |
K |
A |
-2.3858 |
|
| 184 |
A |
A |
-2.1006 |
|
| 185 |
D |
A |
-2.7510 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.8461 |
|
| 188 |
K |
A |
-3.8310 |
|
| 189 |
H |
A |
-3.3224 |
|
| 190 |
K |
A |
-3.2890 |
|
| 191 |
V |
A |
-1.6104 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
0.0000 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-1.1729 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.2784 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.5598 |
|
| 200 |
G |
A |
-0.4216 |
|
| 201 |
L |
A |
-0.2281 |
|
| 202 |
S |
A |
-0.4480 |
|
| 203 |
S |
A |
-0.3839 |
|
| 204 |
P |
A |
-0.5890 |
|
| 205 |
V |
A |
-0.0157 |
|
| 206 |
T |
A |
-0.3999 |
|
| 207 |
K |
A |
-0.3047 |
|
| 208 |
S |
A |
-0.4184 |
|
| 209 |
F |
A |
-0.6735 |
|
| 210 |
N |
A |
-1.8836 |
|
| 211 |
R |
A |
-2.5261 |
|
| 212 |
G |
A |
-1.5037 |
|
| 213 |
A |
A |
-0.8783 |
|