Project name: 4edw:L
Status: done
submitted: 2019-03-20 20:14:42, status changed: 2019-03-20 20:24:13
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSSLSASVGDRVTITCRASQSISNNLNWYQQKPGKAPKLLIYYTSRFHSGVPSRFSGSGSGTDFTFTISSLQPEDIATYYCQQEHTLPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.4745
-
Maximal score value
-
1.5751
-
Average score
-
-0.7425
-
Total score value
-
-158.8854
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.8019 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
Q |
L |
-1.9678 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-1.2430 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.7924 |
|
| 8 |
P |
L |
-0.4930 |
|
| 9 |
S |
L |
-0.6898 |
|
| 10 |
S |
L |
-0.5161 |
|
| 11 |
L |
L |
-0.3972 |
|
| 12 |
S |
L |
-0.8666 |
|
| 13 |
A |
L |
-1.0271 |
|
| 14 |
S |
L |
-0.9320 |
|
| 15 |
V |
L |
-0.0733 |
|
| 16 |
G |
L |
-0.7305 |
|
| 17 |
D |
L |
-1.5622 |
|
| 18 |
R |
L |
-2.2578 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6108 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.7870 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.6488 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-2.0205 |
|
| 27 |
Q |
L |
-2.1789 |
|
| 28 |
S |
L |
-1.4838 |
|
| 29 |
I |
L |
0.0000 |
|
| 30 |
S |
L |
-0.9853 |
|
| 31 |
N |
L |
-0.8319 |
|
| 32 |
N |
L |
-0.6679 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
N |
L |
0.2775 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.0036 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.3519 |
|
| 39 |
K |
L |
-1.8979 |
|
| 40 |
P |
L |
-1.6143 |
|
| 41 |
G |
L |
-1.5938 |
|
| 42 |
K |
L |
-2.1258 |
|
| 43 |
A |
L |
-1.2875 |
|
| 44 |
P |
L |
-1.2764 |
|
| 45 |
K |
L |
-1.6212 |
|
| 46 |
L |
L |
-0.2886 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
0.2276 |
|
| 50 |
Y |
L |
0.3541 |
|
| 51 |
T |
L |
0.0000 |
|
| 52 |
S |
L |
-0.7624 |
|
| 53 |
R |
L |
-1.2141 |
|
| 54 |
F |
L |
-0.0992 |
|
| 55 |
H |
L |
-0.8094 |
|
| 56 |
S |
L |
-0.4437 |
|
| 57 |
G |
L |
-0.4923 |
|
| 58 |
V |
L |
-0.2724 |
|
| 59 |
P |
L |
-0.2765 |
|
| 60 |
S |
L |
-0.3275 |
|
| 61 |
R |
L |
-0.7848 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.5010 |
|
| 64 |
G |
L |
-0.4077 |
|
| 65 |
S |
L |
-0.7931 |
|
| 66 |
G |
L |
-1.0256 |
|
| 67 |
S |
L |
-1.1362 |
|
| 68 |
G |
L |
-1.2631 |
|
| 69 |
T |
L |
-1.6574 |
|
| 70 |
D |
L |
-1.8155 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.7131 |
|
| 73 |
F |
L |
0.0000 |
|
| 74 |
T |
L |
-0.6250 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.3542 |
|
| 77 |
S |
L |
-1.1217 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-0.9471 |
|
| 80 |
P |
L |
-1.8281 |
|
| 81 |
E |
L |
-2.2149 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
I |
L |
0.0000 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
-0.5859 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.1502 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
E |
L |
-0.1641 |
|
| 92 |
H |
L |
-0.8543 |
|
| 93 |
T |
L |
0.1389 |
|
| 94 |
L |
L |
1.2848 |
|
| 95 |
P |
L |
0.9220 |
|
| 96 |
Y |
L |
1.3398 |
|
| 97 |
T |
L |
0.5990 |
|
| 98 |
F |
L |
1.1826 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
Q |
L |
-1.0521 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-0.7969 |
|
| 104 |
L |
L |
0.0000 |
|
| 105 |
E |
L |
-1.3652 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.5052 |
|
| 108 |
R |
L |
-1.0385 |
|
| 109 |
T |
L |
-0.0954 |
|
| 110 |
V |
L |
0.6190 |
|
| 111 |
A |
L |
-0.1441 |
|
| 112 |
A |
L |
-0.1429 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
0.0536 |
|
| 115 |
V |
L |
0.5210 |
|
| 116 |
F |
L |
1.4900 |
|
| 117 |
I |
L |
1.3505 |
|
| 118 |
F |
L |
1.5751 |
|
| 119 |
P |
L |
0.3428 |
|
| 120 |
P |
L |
-0.5921 |
|
| 121 |
S |
L |
-1.7054 |
|
| 122 |
D |
L |
-3.1545 |
|
| 123 |
E |
L |
-3.4745 |
|
| 124 |
Q |
L |
-2.5152 |
|
| 125 |
L |
L |
-2.5987 |
|
| 126 |
K |
L |
-3.0793 |
|
| 127 |
S |
L |
-1.9055 |
|
| 128 |
G |
L |
-1.4597 |
|
| 129 |
T |
L |
-1.1702 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0358 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7798 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.7550 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.3995 |
|
| 138 |
N |
L |
-1.2066 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.8349 |
|
| 142 |
R |
L |
-3.2189 |
|
| 143 |
E |
L |
-3.1738 |
|
| 144 |
A |
L |
-2.2491 |
|
| 145 |
K |
L |
-2.0897 |
|
| 146 |
V |
L |
-0.8651 |
|
| 147 |
Q |
L |
-0.3858 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.4128 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.8328 |
|
| 152 |
N |
L |
-1.4774 |
|
| 153 |
A |
L |
-0.2158 |
|
| 154 |
L |
L |
0.7857 |
|
| 155 |
Q |
L |
0.0183 |
|
| 156 |
S |
L |
-0.4582 |
|
| 157 |
G |
L |
-0.9751 |
|
| 158 |
N |
L |
-0.9064 |
|
| 159 |
S |
L |
-1.3234 |
|
| 160 |
Q |
L |
-2.2021 |
|
| 161 |
E |
L |
-2.0954 |
|
| 162 |
S |
L |
-1.1938 |
|
| 163 |
V |
L |
-0.8728 |
|
| 164 |
T |
L |
-1.2461 |
|
| 165 |
E |
L |
-2.4056 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.5654 |
|
| 168 |
S |
L |
-2.6211 |
|
| 169 |
K |
L |
-2.8368 |
|
| 170 |
D |
L |
-2.1934 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.9369 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.3253 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.5731 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.3791 |
|
| 181 |
L |
L |
-0.6576 |
|
| 182 |
S |
L |
-1.0675 |
|
| 183 |
K |
L |
-2.1880 |
|
| 184 |
A |
L |
-1.8678 |
|
| 185 |
D |
L |
-2.5302 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.2823 |
|
| 188 |
K |
L |
-3.4299 |
|
| 189 |
H |
L |
-2.6797 |
|
| 190 |
K |
L |
-2.5879 |
|
| 191 |
V |
L |
-0.9933 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.5960 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.0937 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.5046 |
|
| 200 |
G |
L |
-0.3684 |
|
| 201 |
L |
L |
-0.2143 |
|
| 202 |
S |
L |
-0.4726 |
|
| 203 |
S |
L |
-0.3998 |
|
| 204 |
P |
L |
-0.4864 |
|
| 205 |
V |
L |
0.0318 |
|
| 206 |
T |
L |
-0.2908 |
|
| 207 |
K |
L |
-0.2445 |
|
| 208 |
S |
L |
-0.1980 |
|
| 209 |
F |
L |
-0.4686 |
|
| 210 |
N |
L |
-1.4858 |
|
| 211 |
R |
L |
-1.9170 |
|
| 212 |
G |
L |
-1.7349 |
|
| 213 |
E |
L |
-2.0412 |
|
| 214 |
C |
L |
-0.5350 |
|