Project name: b10ab2dae98e47f

Chain sequence(s)	A: VQALFNEISADAVFVTYDGQNIKKYGTHLDRAKTAYIPASTFIANALIGLENHKATSTEIFKWDGKPRFFKAWDKDFTLGEAMQASTVPVYQELARRIGPSLMQSELQRIGYGNMQIGTEVDQFWLKGPLTITPIQEVKFVYDLAQGQLPFKPEVQQQVKEMLYVERRGENRLYAKSGWGMAVDPQVGWYVGFVEKADGQVVAFALNMQMKAGDDIALRKQLSLDVLDKLGVFHYL
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.2354
• Maximal score value: 1.8625
• Average score: -0.7616
• Total score value: -179.7387

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
44	V	A	0.5199
45	Q	A	-0.8387
46	A	A	-0.3721
47	L	A	0.2190
48	F	A	0.0000
49	N	A	-1.8497
50	E	A	-1.7163
51	I	A	-0.2477
52	S	A	-0.6706
53	A	A	-1.0314
54	D	A	-1.0745
55	A	A	0.0000
56	V	A	0.0000
57	F	A	0.0000
58	V	A	0.0000
59	T	A	0.0000
60	Y	A	0.0000
61	D	A	-1.7470
62	G	A	-1.5053
63	Q	A	-1.9561
64	N	A	-1.9438
65	I	A	-0.9847
66	K	A	-1.1912
67	K	A	-1.2019
68	Y	A	-0.4508
69	G	A	-0.6300
70	T	A	-0.9600
71	H	A	-1.0737
72	L	A	-0.9109
73	D	A	-2.1716
74	R	A	0.0000
75	A	A	0.0000
76	K	A	-2.1455
77	T	A	-1.1836
78	A	A	-0.4241
79	Y	A	-0.2451
80	I	A	0.0000
81	P	A	0.0000
82	A	A	0.0000
83	S	A	0.1062
84	T	A	0.0000
85	F	A	0.0000
87	I	A	0.0000
88	A	A	0.0000
89	N	A	0.0000
90	A	A	0.0000
91	L	A	0.0000
92	I	A	0.0000
93	G	A	0.0000
94	L	A	0.0000
95	E	A	-1.2345
96	N	A	-1.0640
97	H	A	-1.6040
98	K	A	-1.6203
99	A	A	0.0000
100	T	A	-0.3979
101	S	A	-0.4268
102	T	A	0.1184
103	E	A	0.2203
104	I	A	0.9815
105	F	A	0.0000
106	K	A	-2.1991
107	W	A	-2.5290
108	D	A	-3.2354
109	G	A	-2.7571
110	K	A	-2.8126
111	P	A	-1.5214
112	R	A	-0.3970
113	F	A	1.8625
114	F	A	0.9645
115	K	A	-1.1924
116	A	A	-0.6203
117	W	A	0.0000
118	D	A	-2.1782
119	K	A	-3.1523
120	D	A	-2.0429
121	F	A	0.0000
122	T	A	-0.3370
123	L	A	0.0000
124	G	A	-1.3282
125	E	A	-1.7893
126	A	A	0.0000
127	M	A	0.0000
128	Q	A	-1.5520
129	A	A	-0.8285
130	S	A	-0.5716
131	T	A	0.0000
132	V	A	0.3372
133	P	A	0.0010
134	V	A	0.0000
135	Y	A	-0.6282
136	Q	A	-1.3204
137	E	A	-1.8309
138	L	A	0.0000
139	A	A	0.0000
140	R	A	-2.8543
141	R	A	-2.0370
142	I	A	0.0000
143	G	A	-1.2640
144	P	A	-1.1090
145	S	A	-0.2923
146	L	A	-0.1237
147	M	A	0.0000
148	Q	A	-1.0216
149	S	A	-1.0226
150	E	A	0.0000
151	L	A	0.0000
152	Q	A	-2.0551
153	R	A	-1.8995
154	I	A	-0.9765
155	G	A	-1.2373
156	Y	A	0.0000
157	G	A	-0.6877
158	N	A	-0.9850
159	M	A	-1.2060
160	Q	A	-1.3924
161	I	A	0.0000
162	G	A	-1.3714
163	T	A	-1.3503
164	E	A	-2.2082
165	V	A	0.0000
166	D	A	0.0000
167	Q	A	-1.5076
168	F	A	0.0000
169	W	A	0.0000
170	L	A	-0.5336
171	K	A	-1.7514
172	G	A	-1.3365
173	P	A	-1.0381
174	L	A	0.0000
175	T	A	-0.4998
176	I	A	0.0000
177	T	A	-0.7154
178	P	A	0.0000
179	I	A	0.0000
180	Q	A	-1.1034
181	E	A	0.0000
182	V	A	0.0000
183	K	A	-1.1094
184	F	A	0.0000
185	V	A	0.0000
186	Y	A	-0.9079
187	D	A	-1.4162
188	L	A	0.0000
189	A	A	-1.0289
190	Q	A	-1.5165
191	G	A	-1.9290
192	Q	A	-1.8403
193	L	A	0.0000
194	P	A	-0.8927
195	F	A	0.0000
196	K	A	-1.7271
197	P	A	-2.1137
198	E	A	-2.5974
199	V	A	0.0000
200	Q	A	0.0000
201	Q	A	-2.7798
202	Q	A	-2.1262
203	V	A	0.0000
204	K	A	-1.8559
205	E	A	-2.1448
206	M	A	0.0000
207	L	A	0.0000
208	Y	A	-0.8245
209	V	A	-0.5754
210	E	A	-1.7223
211	R	A	-2.9000
212	R	A	0.0000
213	G	A	-1.8307
214	E	A	-3.1008
215	N	A	-3.0721
216	R	A	-2.4654
217	L	A	0.0000
218	Y	A	0.0000
219	A	A	0.0000
220	K	A	0.0000
221	S	A	-0.1272
222	G	A	0.0000
223	W	A	0.5606
224	G	A	0.0000
225	M	A	-0.0776
226	A	A	-0.3806
227	V	A	-0.8868
228	D	A	-1.9570
229	P	A	-1.5785
230	Q	A	-1.0859
231	V	A	0.0000
232	G	A	0.0000
233	W	A	0.0000
234	Y	A	0.0000
235	V	A	0.0000
236	G	A	0.0000
237	F	A	0.0000
238	V	A	0.0000
239	E	A	-1.8362
240	K	A	-2.3379
241	A	A	-2.3821
242	D	A	-2.7642
243	G	A	-2.2276
244	Q	A	-2.1260
245	V	A	-1.1722
246	V	A	-0.3908
247	A	A	0.0000
248	F	A	0.0000
249	A	A	0.0000
250	L	A	0.0000
251	N	A	0.0000
252	M	A	0.0000
253	Q	A	-1.3036
254	M	A	0.0000
255	K	A	-2.6103
256	A	A	-1.8768
257	G	A	-1.7595
258	D	A	-2.7078
259	D	A	-1.8332
260	I	A	0.5132
261	A	A	-0.1539
262	L	A	-0.5481
263	R	A	0.0000
264	K	A	-0.9132
265	Q	A	-1.1718
266	L	A	-0.4517
267	S	A	0.0000
268	L	A	-0.7583
269	D	A	-0.7252
270	V	A	0.0000
271	L	A	0.0000
272	D	A	-0.8588
273	K	A	-1.2059
274	L	A	-0.5336
275	G	A	-0.9899
276	V	A	0.0000
277	F	A	0.0000
278	H	A	-0.6825
279	Y	A	0.6958
280	L	A	1.3302