Project name: 6bae:B

Chain sequence(s)	B: EVQLVESGGGLVQPGGSLRLSSCAASGFNNIKDTYIHWVRQSPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMMNSLRAEDTAIYYCCSRWGGDGFYAMDYWGQGTLVTVSSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEEPVTVSWNSGALTSGVHTFPCVLQSSGLYSLSSVVTTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8899
• Maximal score value: 2.5681
• Average score: -0.5742
• Total score value: -128.0462

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	B	-2.1940
2	V	B	-1.5558
3	Q	B	-1.4056
4	L	B	0.0000
5	V	B	0.6876
6	E	B	0.0000
7	S	B	-0.4504
8	G	B	-0.9112
9	G	B	-0.4481
10	G	B	-0.4593
11	L	B	-0.1344
12	V	B	0.0000
13	Q	B	-1.6594
14	P	B	-1.7154
15	G	B	-1.4385
16	G	B	-1.1488
17	S	B	-1.1143
18	L	B	-1.0942
19	R	B	-1.9165
20	L	B	0.0000
21	S	B	-0.3989
22	C	B	0.0000
23	A	B	-0.2179
24	A	B	0.0000
25	S	B	-1.2971
26	G	B	-1.5322
27	F	B	-1.6998
28	N	B	-2.3295
29	I	B	0.0000
30	K	B	-2.7295
31	D	B	-2.8899
32	T	B	0.0000
33	Y	B	0.0413
34	I	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.3752
40	S	B	-1.1236
41	P	B	-1.1679
42	G	B	-1.7413
43	K	B	-2.1926
44	G	B	-0.7882
45	L	B	0.6107
46	E	B	-0.1140
47	W	B	0.2995
48	V	B	0.0000
49	A	B	0.0000
50	R	B	-0.9666
51	I	B	0.0000
52	Y	B	-0.4789
53	P	B	-1.1513
54	T	B	-1.1729
55	N	B	-0.9367
56	G	B	-0.3650
57	Y	B	0.4091
58	T	B	-0.6243
59	R	B	-2.1113
60	Y	B	-1.8351
61	A	B	-1.7453
62	D	B	-2.6756
63	S	B	-1.5775
64	V	B	0.0000
65	K	B	-2.8583
66	G	B	-1.7857
67	R	B	-1.5954
68	F	B	0.0000
69	T	B	-1.1131
70	I	B	0.0000
71	S	B	-0.2098
72	A	B	-0.7934
73	D	B	-1.4201
74	T	B	-1.6153
75	S	B	-1.5710
76	K	B	-2.2427
77	N	B	-1.8028
78	T	B	0.0000
79	A	B	0.0000
80	Y	B	-0.4763
81	L	B	0.0000
82	Q	B	-1.0745
83	M	B	0.0000
84	N	B	-1.3892
85	S	B	-1.2648
86	L	B	0.0000
87	R	B	-2.3516
88	A	B	-1.7570
89	E	B	-2.5979
90	D	B	0.0000
91	T	B	-0.8283
92	A	B	0.0000
93	I	B	0.5115
94	Y	B	0.0000
95	Y	B	0.4417
96	C	B	0.0000
97	S	B	0.0000
98	R	B	0.0000
99	W	B	0.6818
100	G	B	0.4071
101	G	B	0.0000
102	D	B	-1.5078
103	G	B	-0.2104
104	F	B	1.7563
105	Y	B	1.9587
106	A	B	1.2876
107	M	B	0.9205
108	D	B	0.1768
109	Y	B	0.0438
110	W	B	0.3089
111	G	B	0.0000
112	Q	B	-0.7663
113	G	B	-0.0989
114	T	B	0.1271
115	L	B	0.3654
116	V	B	0.0000
117	T	B	-0.4023
118	V	B	0.0000
119	S	B	-0.8058
120	S	B	-0.7349
121	A	B	-0.4958
122	S	B	-0.6264
123	T	B	-0.7713
124	K	B	-1.5206
125	G	B	-1.6441
126	P	B	-0.7257
127	S	B	-0.1967
128	V	B	0.0000
129	F	B	0.9767
130	P	B	0.1043
131	L	B	0.3169
132	A	B	-1.0590
133	P	B	0.0000
134	S	B	-1.3418
135	S	B	-1.1514
136	K	B	-1.8942
137	S	B	-0.9945
138	T	B	-0.9897
139	S	B	-0.9472
140	G	B	-0.8554
141	G	B	-0.9148
142	T	B	-0.6302
143	A	B	0.0000
144	A	B	-0.2055
145	L	B	0.0000
146	G	B	0.0000
147	C	B	0.0000
148	L	B	0.6709
149	V	B	0.0000
150	K	B	-0.2959
151	D	B	-0.6310
152	Y	B	0.0000
153	F	B	0.0000
154	P	B	0.0000
155	E	B	-0.3860
156	P	B	-0.5855
157	V	B	-0.4074
158	T	B	-0.4808
159	V	B	-0.0653
160	S	B	-0.3453
161	W	B	0.0000
162	N	B	-0.7576
163	S	B	-0.6371
164	G	B	-0.5022
165	A	B	-0.2325
166	L	B	-0.0353
167	T	B	-0.3241
168	S	B	-0.3729
169	G	B	-0.4640
170	V	B	-0.1452
171	H	B	-0.5891
172	T	B	0.1302
173	F	B	1.0287
174	P	B	0.8292
175	C	B	1.4665
176	V	B	2.5681
177	L	B	2.1969
178	Q	B	0.7502
179	S	B	0.1229
180	S	B	-0.2216
181	G	B	0.1907
182	L	B	0.1968
183	Y	B	0.8346
184	S	B	0.0000
185	L	B	0.0000
186	S	B	0.6765
187	S	B	0.0000
188	V	B	0.3388
189	V	B	0.0000
190	T	B	-0.2518
191	V	B	0.0000
192	P	B	-0.6134
193	S	B	-0.5441
194	S	B	-0.5265
195	S	B	-0.5105
196	L	B	-0.6871
197	G	B	-1.0728
198	T	B	-0.6759
199	Q	B	-1.1971
200	T	B	-1.1319
201	Y	B	0.0000
202	I	B	-1.3730
203	C	B	0.0000
204	N	B	-1.3347
205	V	B	0.0000
206	N	B	-1.6799
207	H	B	0.0000
208	K	B	-2.7353
209	P	B	-1.6548
210	S	B	-1.9104
211	N	B	-2.5680
212	T	B	-2.0694
213	K	B	-2.5967
214	V	B	-1.5023
215	D	B	-2.2324
216	K	B	-1.9561
217	K	B	-2.4220
218	V	B	0.0000
219	E	B	-2.8687
220	P	B	-1.8623
221	K	B	-2.1238
222	S	B	-0.9768
223	C	B	0.1979