| Chain sequence(s) |
A: ASPERKAAVALRSLFTFVAARVVLEQLQGPGGPETTYNQQAYLDLMDFLGTPMKGDGGDEWMAAVMRKNHALALRLMEVREAYLDEFEWGKTMEMASRETREANTRLMRAAAM R: WKEIKF B: ASPERKAAVALRSLFTFVAARVVLEQLQGPGGPETTYNQQAYLDLMDFLGTPMKGDGGDEWMAAVMRKNHALALRLMEVREAYLDEFEWGKTMEMASRETREANTRLMRAAAM |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 44 | A | A | -0.7420 | |
| 45 | S | A | -1.0027 | |
| 46 | P | A | -0.9324 | |
| 47 | E | A | -1.8010 | |
| 48 | R | A | -2.4092 | |
| 49 | K | A | -1.4647 | |
| 50 | A | A | 0.0000 | |
| 51 | A | A | 0.0000 | |
| 52 | V | A | -0.9216 | |
| 53 | A | A | -0.5159 | |
| 54 | L | A | 0.0000 | |
| 55 | R | A | 0.0000 | |
| 56 | S | A | -0.2187 | |
| 57 | L | A | 0.3750 | |
| 58 | F | A | 0.0000 | |
| 59 | T | A | 0.0000 | |
| 60 | F | A | 0.8860 | |
| 61 | V | A | 0.4375 | |
| 62 | A | A | 0.0000 | |
| 63 | A | A | 0.0000 | |
| 64 | R | A | -1.1204 | |
| 65 | V | A | -0.7254 | |
| 66 | V | A | 0.0000 | |
| 67 | L | A | -1.1233 | |
| 68 | E | A | -2.7056 | |
| 69 | Q | A | -2.4189 | |
| 70 | L | A | -1.9993 | |
| 71 | Q | A | -2.3163 | |
| 72 | G | A | -2.0455 | |
| 73 | P | A | -1.4409 | |
| 74 | G | A | -1.1999 | |
| 75 | G | A | -1.6652 | |
| 76 | P | A | -1.9363 | |
| 77 | E | A | -2.2148 | |
| 78 | T | A | -1.0170 | |
| 79 | T | A | -0.4774 | |
| 80 | Y | A | 0.3274 | |
| 81 | N | A | -1.0117 | |
| 82 | Q | A | -1.0444 | |
| 83 | Q | A | -0.4332 | |
| 84 | A | A | 0.0000 | |
| 85 | Y | A | -0.2172 | |
| 86 | L | A | 0.7195 | |
| 87 | D | A | -0.5664 | |
| 88 | L | A | 0.0000 | |
| 89 | M | A | 0.1867 | |
| 90 | D | A | -1.1500 | |
| 91 | F | A | -0.5346 | |
| 92 | L | A | -0.0933 | |
| 93 | G | A | -0.7196 | |
| 94 | T | A | -0.6802 | |
| 95 | P | A | -0.8595 | |
| 96 | M | A | -1.2481 | |
| 97 | K | A | -2.7595 | |
| 98 | G | A | -2.6455 | |
| 99 | D | A | -2.5780 | |
| 100 | G | A | 0.0000 | |
| 101 | G | A | 0.0000 | |
| 102 | D | A | -1.9493 | |
| 103 | E | A | -2.8488 | |
| 104 | W | A | 0.0000 | |
| 105 | M | A | 0.0000 | |
| 106 | A | A | -1.5654 | |
| 107 | A | A | -1.6702 | |
| 108 | V | A | 0.0000 | |
| 109 | M | A | 0.0000 | |
| 110 | R | A | -2.7890 | |
| 111 | K | A | -2.7290 | |
| 112 | N | A | 0.0000 | |
| 113 | H | A | -1.3758 | |
| 114 | A | A | -0.6151 | |
| 115 | L | A | 0.0000 | |
| 116 | A | A | 0.0000 | |
| 117 | L | A | -0.6704 | |
| 118 | R | A | -1.5337 | |
| 119 | L | A | 0.0000 | |
| 120 | M | A | 0.0000 | |
| 121 | E | A | -2.3673 | |
| 122 | V | A | 0.0000 | |
| 123 | R | A | 0.0000 | |
| 124 | E | A | -2.4341 | |
| 125 | A | A | -1.5885 | |
| 126 | Y | A | -1.4686 | |
| 127 | L | A | -2.0521 | |
| 128 | D | A | -2.7614 | |
| 129 | E | A | -2.9259 | |
| 130 | F | A | 0.0000 | |
| 131 | E | A | -2.8078 | |
| 132 | W | A | -1.6915 | |
| 133 | G | A | -1.6711 | |
| 134 | K | A | -2.6616 | |
| 135 | T | A | 0.0000 | |
| 136 | M | A | -1.5461 | |
| 137 | E | A | -2.8627 | |
| 138 | M | A | -2.2250 | |
| 139 | A | A | 0.0000 | |
| 140 | S | A | -2.7425 | |
| 141 | R | A | -3.8143 | |
| 142 | E | A | -3.3262 | |
| 143 | T | A | 0.0000 | |
| 144 | R | A | -4.1851 | |
| 145 | E | A | -4.0238 | |
| 146 | A | A | -2.7917 | |
| 147 | N | A | 0.0000 | |
| 148 | T | A | -2.5324 | |
| 149 | R | A | -3.0340 | |
| 150 | L | A | -1.3235 | |
| 151 | M | A | -1.0316 | |
| 152 | R | A | -2.0599 | |
| 153 | A | A | -1.0009 | |
| 154 | A | A | -0.7188 | |
| 155 | A | A | -0.0925 | |
| 156 | M | A | 0.8364 | |
| 44 | A | B | -0.7013 | |
| 45 | S | B | -0.9484 | |
| 46 | P | B | -1.0119 | |
| 47 | E | B | -1.7323 | |
| 48 | R | B | -2.1838 | |
| 49 | K | B | -1.9396 | |
| 50 | A | B | 0.0000 | |
| 51 | A | B | 0.0000 | |
| 52 | V | B | -0.8968 | |
| 53 | A | B | -0.7751 | |
| 54 | L | B | 0.0000 | |
| 55 | R | B | 0.0000 | |
| 56 | S | B | 0.0000 | |
| 57 | L | B | 0.0000 | |
| 58 | F | B | 0.0000 | |
| 59 | T | B | 0.0000 | |
| 60 | F | B | 0.2804 | |
| 61 | V | B | 0.0000 | |
| 62 | A | B | 0.0000 | |
| 63 | A | B | 0.0000 | |
| 64 | R | B | -1.5274 | |
| 65 | V | B | -0.6048 | |
| 66 | V | B | 0.0000 | |
| 67 | L | B | 0.0000 | |
| 68 | E | B | -2.6428 | |
| 69 | Q | B | -2.1762 | |
| 70 | L | B | 0.0000 | |
| 71 | Q | B | -2.2350 | |
| 72 | G | B | -1.8812 | |
| 73 | P | B | -1.3072 | |
| 74 | G | B | -1.0748 | |
| 75 | G | B | -1.4964 | |
| 76 | P | B | -1.8669 | |
| 77 | E | B | -2.1249 | |
| 78 | T | B | -0.9441 | |
| 79 | T | B | -0.3834 | |
| 80 | Y | B | 0.4076 | |
| 81 | N | B | -0.8637 | |
| 82 | Q | B | -1.0423 | |
| 83 | Q | B | -0.6107 | |
| 84 | A | B | -0.6381 | |
| 85 | Y | B | 0.0000 | |
| 86 | L | B | 0.0158 | |
| 87 | D | B | 0.0000 | |
| 88 | L | B | 0.0000 | |
| 89 | M | B | 0.0000 | |
| 90 | D | B | -1.5492 | |
| 91 | F | B | -0.7705 | |
| 92 | L | B | -0.7428 | |
| 93 | G | B | -1.1191 | |
| 94 | T | B | -0.7934 | |
| 95 | P | B | -0.7260 | |
| 96 | M | B | -1.1425 | |
| 97 | K | B | -2.5530 | |
| 98 | G | B | -1.9439 | |
| 99 | D | B | -1.8958 | |
| 100 | G | B | 0.0000 | |
| 101 | G | B | 0.0000 | |
| 102 | D | B | -1.6511 | |
| 103 | E | B | -2.5012 | |
| 104 | W | B | 0.0000 | |
| 105 | M | B | 0.0000 | |
| 106 | A | B | -1.3809 | |
| 107 | A | B | -1.5610 | |
| 108 | V | B | 0.0000 | |
| 109 | M | B | 0.0000 | |
| 110 | R | B | -2.8641 | |
| 111 | K | B | -2.7878 | |
| 112 | N | B | -1.8625 | |
| 113 | H | B | -1.4526 | |
| 114 | A | B | -0.5336 | |
| 115 | L | B | 0.0000 | |
| 116 | A | B | 0.0000 | |
| 117 | L | B | -0.2716 | |
| 118 | R | B | -1.1037 | |
| 119 | L | B | 0.0000 | |
| 120 | M | B | 0.0000 | |
| 121 | E | B | -2.1917 | |
| 122 | V | B | 0.0000 | |
| 123 | R | B | 0.0000 | |
| 124 | E | B | -2.1031 | |
| 125 | A | B | -1.5834 | |
| 126 | Y | B | -1.5560 | |
| 127 | L | B | -1.8186 | |
| 128 | D | B | -2.7872 | |
| 129 | E | B | -2.9216 | |
| 130 | F | B | 0.0000 | |
| 131 | E | B | -2.8572 | |
| 132 | W | B | 0.0000 | |
| 133 | G | B | -1.7441 | |
| 134 | K | B | -2.7393 | |
| 135 | T | B | 0.0000 | |
| 136 | M | B | -1.8723 | |
| 137 | E | B | -2.9744 | |
| 138 | M | B | -2.3658 | |
| 139 | A | B | 0.0000 | |
| 140 | S | B | -2.7767 | |
| 141 | R | B | -3.8827 | |
| 142 | E | B | -3.3579 | |
| 143 | T | B | 0.0000 | |
| 144 | R | B | -4.2119 | |
| 145 | E | B | -4.1214 | |
| 146 | A | B | 0.0000 | |
| 147 | N | B | 0.0000 | |
| 148 | T | B | -2.6443 | |
| 149 | R | B | -3.1490 | |
| 150 | L | B | 0.0000 | |
| 151 | M | B | -1.2699 | |
| 152 | R | B | -2.1678 | |
| 153 | A | B | -1.0980 | |
| 154 | A | B | -0.7608 | |
| 155 | A | B | -0.0229 | |
| 156 | M | B | 0.8200 | |
| 462 | W | R | 0.5668 | |
| 463 | K | R | -1.0385 | |
| 464 | E | R | -1.8789 | |
| 465 | I | R | -1.1261 | |
| 466 | K | R | -1.2464 | |
| 467 | F | R | 0.9934 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine