| Chain sequence(s) |
A: DIQMTQSPSSLSASVGDRVTITCRASQDIASWLNWYQQKPGKAPKLLIYAASRLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSFPWTFGQGTKVEIK B: EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYEMSWVRQAPGKGLEWVSAIRGSGSDTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKEGEATWSGDFDIWGQGTLVTVSS |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | E | B | -2.0825 | |
| 2 | V | B | -1.1665 | |
| 3 | Q | B | -1.2249 | |
| 4 | L | B | 0.0000 | |
| 5 | V | B | 1.0247 | |
| 6 | E | B | 0.1229 | |
| 7 | S | B | -0.3899 | |
| 8 | G | B | -0.8978 | |
| 9 | G | B | -0.3411 | |
| 10 | G | B | 0.4122 | |
| 11 | L | B | 1.1879 | |
| 12 | V | B | 0.0000 | |
| 13 | Q | B | -1.4449 | |
| 14 | P | B | -1.7685 | |
| 15 | G | B | -1.5849 | |
| 16 | G | B | -1.0977 | |
| 17 | S | B | -1.1026 | |
| 18 | L | B | -1.0946 | |
| 19 | R | B | -2.0096 | |
| 20 | L | B | 0.0000 | |
| 21 | S | B | -0.2650 | |
| 22 | C | B | 0.0000 | |
| 23 | A | B | -0.0999 | |
| 24 | A | B | 0.0000 | |
| 25 | S | B | -0.7903 | |
| 26 | G | B | -1.0822 | |
| 27 | F | B | -0.2953 | |
| 28 | T | B | -0.2359 | |
| 29 | F | B | 0.0000 | |
| 30 | S | B | -1.3599 | |
| 31 | S | B | -0.6681 | |
| 32 | Y | B | -0.5582 | |
| 33 | E | B | 0.0000 | |
| 34 | M | B | 0.0000 | |
| 35 | S | B | 0.0000 | |
| 36 | W | B | 0.0000 | |
| 37 | V | B | 0.0000 | |
| 38 | R | B | -0.8106 | |
| 39 | Q | B | -1.0569 | |
| 40 | A | B | -1.3376 | |
| 41 | P | B | -1.0041 | |
| 42 | G | B | -1.4649 | |
| 43 | K | B | -2.4817 | |
| 44 | G | B | -1.7669 | |
| 45 | L | B | 0.0000 | |
| 46 | E | B | -1.3753 | |
| 47 | W | B | 0.0000 | |
| 48 | V | B | 0.0000 | |
| 49 | S | B | 0.0000 | |
| 50 | A | B | 0.0132 | |
| 51 | I | B | 0.0000 | |
| 52 | R | B | -1.2283 | |
| 53 | G | B | -1.4405 | |
| 54 | S | B | -1.1372 | |
| 55 | G | B | -1.3960 | |
| 56 | S | B | -0.8616 | |
| 57 | D | B | -0.7169 | |
| 58 | T | B | -0.3510 | |
| 59 | Y | B | 0.2349 | |
| 60 | Y | B | -0.5239 | |
| 61 | A | B | -1.2008 | |
| 62 | D | B | -2.3420 | |
| 63 | S | B | -1.6446 | |
| 64 | V | B | 0.0000 | |
| 65 | K | B | -2.4279 | |
| 66 | G | B | -1.7040 | |
| 67 | R | B | -1.2839 | |
| 68 | F | B | 0.0000 | |
| 69 | T | B | -0.7294 | |
| 70 | I | B | 0.0000 | |
| 71 | S | B | -0.4326 | |
| 72 | R | B | -1.3789 | |
| 73 | D | B | -2.2330 | |
| 74 | N | B | -2.7001 | |
| 75 | S | B | -2.1376 | |
| 76 | K | B | -2.7347 | |
| 77 | N | B | -2.1275 | |
| 78 | T | B | -1.1017 | |
| 79 | L | B | 0.0000 | |
| 80 | Y | B | -0.2128 | |
| 81 | L | B | 0.0000 | |
| 82 | Q | B | -1.0380 | |
| 83 | M | B | 0.0000 | |
| 84 | N | B | -1.3791 | |
| 85 | S | B | -1.2284 | |
| 86 | L | B | 0.0000 | |
| 87 | R | B | -2.7513 | |
| 88 | A | B | -2.0074 | |
| 89 | E | B | -2.3135 | |
| 90 | D | B | 0.0000 | |
| 91 | T | B | -0.7774 | |
| 92 | A | B | 0.0000 | |
| 93 | V | B | 0.3020 | |
| 94 | Y | B | 0.0000 | |
| 95 | Y | B | 0.0000 | |
| 96 | C | B | 0.0000 | |
| 97 | A | B | 0.0000 | |
| 98 | K | B | 0.0000 | |
| 99 | E | B | 0.0000 | |
| 100 | G | B | -1.1757 | |
| 101 | E | B | -1.8022 | |
| 102 | A | B | -0.6566 | |
| 103 | T | B | -0.1804 | |
| 104 | W | B | 0.9579 | |
| 105 | S | B | 0.3386 | |
| 106 | G | B | -0.4008 | |
| 107 | D | B | -0.8077 | |
| 108 | F | B | 0.0000 | |
| 109 | D | B | -0.8277 | |
| 110 | I | B | -0.1264 | |
| 111 | W | B | 0.0000 | |
| 112 | G | B | -0.8654 | |
| 113 | Q | B | -1.4725 | |
| 114 | G | B | -0.4824 | |
| 115 | T | B | 0.3300 | |
| 116 | L | B | 1.3807 | |
| 117 | V | B | 0.0000 | |
| 118 | T | B | 0.5467 | |
| 119 | V | B | 0.0000 | |
| 120 | S | B | -0.5995 | |
| 121 | S | B | -0.5577 | |
| 1 | D | A | -2.0802 | |
| 2 | I | A | 0.0000 | |
| 3 | Q | A | -2.0510 | |
| 4 | M | A | 0.0000 | |
| 5 | T | A | -1.1348 | |
| 6 | Q | A | 0.0000 | |
| 7 | S | A | -0.7693 | |
| 8 | P | A | -0.6215 | |
| 9 | S | A | -0.8157 | |
| 10 | S | A | -0.8497 | |
| 11 | L | A | -0.7691 | |
| 12 | S | A | -1.2014 | |
| 13 | A | A | 0.0000 | |
| 14 | S | A | -0.7645 | |
| 15 | V | A | 0.3736 | |
| 16 | G | A | -0.6194 | |
| 17 | D | A | -1.9428 | |
| 18 | R | A | -2.3644 | |
| 19 | V | A | 0.0000 | |
| 20 | T | A | -0.7053 | |
| 21 | I | A | 0.0000 | |
| 22 | T | A | -0.8935 | |
| 23 | C | A | 0.0000 | |
| 24 | R | A | -2.2043 | |
| 25 | A | A | 0.0000 | |
| 26 | S | A | -2.0965 | |
| 27 | Q | A | -2.3527 | |
| 28 | D | A | -2.2895 | |
| 29 | I | A | 0.0000 | |
| 30 | A | A | -0.3596 | |
| 31 | S | A | 0.0137 | |
| 32 | W | A | 0.6650 | |
| 33 | L | A | 0.0000 | |
| 34 | N | A | 0.0000 | |
| 35 | W | A | 0.0000 | |
| 36 | Y | A | 0.0000 | |
| 37 | Q | A | -0.5810 | |
| 38 | Q | A | 0.0000 | |
| 39 | K | A | -1.3872 | |
| 40 | P | A | -1.1222 | |
| 41 | G | A | -1.7429 | |
| 42 | K | A | -2.6303 | |
| 43 | A | A | -1.6752 | |
| 44 | P | A | 0.0000 | |
| 45 | K | A | -1.4980 | |
| 46 | L | A | -0.5278 | |
| 47 | L | A | 0.0000 | |
| 48 | I | A | 0.0000 | |
| 49 | Y | A | 0.0093 | |
| 50 | A | A | -0.0300 | |
| 51 | A | A | 0.0000 | |
| 52 | S | A | -0.7693 | |
| 53 | R | A | -1.2397 | |
| 54 | L | A | 0.3617 | |
| 55 | Q | A | -0.1371 | |
| 56 | S | A | -0.1916 | |
| 57 | G | A | -0.5390 | |
| 58 | V | A | -0.2058 | |
| 59 | P | A | -0.2423 | |
| 60 | S | A | -0.3340 | |
| 61 | R | A | -0.8788 | |
| 62 | F | A | 0.0000 | |
| 63 | S | A | -0.3600 | |
| 64 | G | A | -0.3417 | |
| 65 | S | A | -0.6947 | |
| 66 | G | A | -0.8546 | |
| 67 | S | A | -0.9440 | |
| 68 | G | A | -1.4949 | |
| 69 | T | A | -2.1371 | |
| 70 | D | A | -2.5827 | |
| 71 | F | A | 0.0000 | |
| 72 | T | A | -0.8026 | |
| 73 | L | A | 0.0000 | |
| 74 | T | A | -0.6453 | |
| 75 | I | A | 0.0000 | |
| 76 | S | A | -1.3417 | |
| 77 | S | A | -1.1070 | |
| 78 | L | A | 0.0000 | |
| 79 | Q | A | -0.8083 | |
| 80 | P | A | -1.0665 | |
| 81 | E | A | -1.6232 | |
| 82 | D | A | 0.0000 | |
| 83 | F | A | -0.5754 | |
| 84 | A | A | 0.0000 | |
| 85 | T | A | 0.0000 | |
| 86 | Y | A | 0.0000 | |
| 87 | Y | A | 0.0000 | |
| 88 | C | A | 0.0000 | |
| 89 | Q | A | 0.0000 | |
| 90 | Q | A | 0.0000 | |
| 91 | S | A | 0.8070 | |
| 92 | Y | A | 1.2146 | |
| 93 | S | A | 0.8561 | |
| 94 | F | A | 1.0461 | |
| 95 | P | A | -0.1160 | |
| 96 | W | A | 0.0000 | |
| 97 | T | A | -0.7570 | |
| 98 | F | A | 0.0000 | |
| 99 | G | A | -1.4038 | |
| 100 | Q | A | -1.9138 | |
| 101 | G | A | -1.3958 | |
| 102 | T | A | 0.0000 | |
| 103 | K | A | -1.2539 | |
| 104 | V | A | 0.0000 | |
| 105 | E | A | -1.6799 | |
| 106 | I | A | -0.9865 | |
| 107 | K | A | -1.6759 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine