Project name: 5ff6:A
Status: done
submitted: 2019-03-20 20:26:26, status changed: 2019-03-20 20:38:46
Settings
|
Chain sequence(s)
|
A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGA
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.7756
-
Maximal score value
-
1.8985
-
Average score
-
-0.8727
-
Total score value
-
-185.8766
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-1.4139 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
L |
A |
0.7855 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
T |
A |
-0.2564 |
|
| 6 |
Q |
A |
0.0000 |
|
| 7 |
S |
A |
0.1113 |
|
| 8 |
P |
A |
0.8377 |
|
| 9 |
V |
A |
1.8985 |
|
| 10 |
I |
A |
1.3838 |
|
| 11 |
L |
A |
0.5579 |
|
| 12 |
S |
A |
-0.4079 |
|
| 13 |
V |
A |
-1.3257 |
|
| 14 |
S |
A |
-1.8080 |
|
| 15 |
P |
A |
-2.1846 |
|
| 16 |
G |
A |
-2.1366 |
|
| 17 |
E |
A |
-2.8093 |
|
| 18 |
R |
A |
-3.1441 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
S |
A |
-0.7569 |
|
| 21 |
F |
A |
0.0000 |
|
| 22 |
S |
A |
-0.9060 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.5398 |
|
| 25 |
A |
A |
0.0000 |
|
| 26 |
S |
A |
-1.0414 |
|
| 27 |
Q |
A |
-1.6750 |
|
| 28 |
S |
A |
-1.6138 |
|
| 29 |
I |
A |
0.0000 |
|
| 30 |
G |
A |
-1.1327 |
|
| 31 |
T |
A |
-0.7847 |
|
| 32 |
N |
A |
-0.9699 |
|
| 33 |
I |
A |
0.0000 |
|
| 34 |
H |
A |
0.0000 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.4260 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-2.0347 |
|
| 39 |
R |
A |
-2.8992 |
|
| 40 |
T |
A |
-2.1275 |
|
| 41 |
N |
A |
-2.0964 |
|
| 42 |
G |
A |
-1.8679 |
|
| 43 |
S |
A |
-1.4296 |
|
| 44 |
P |
A |
-1.6284 |
|
| 45 |
R |
A |
-1.9318 |
|
| 46 |
L |
A |
-0.6337 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
K |
A |
-0.7730 |
|
| 50 |
Y |
A |
-0.1331 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
-1.1113 |
|
| 53 |
E |
A |
-1.8806 |
|
| 54 |
S |
A |
-1.1102 |
|
| 55 |
I |
A |
-0.5263 |
|
| 56 |
S |
A |
-0.2718 |
|
| 57 |
G |
A |
-0.4490 |
|
| 58 |
I |
A |
-0.3038 |
|
| 59 |
P |
A |
-0.3184 |
|
| 60 |
S |
A |
-0.5359 |
|
| 61 |
R |
A |
-1.0628 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
-0.8915 |
|
| 64 |
G |
A |
-0.6689 |
|
| 65 |
S |
A |
-0.8165 |
|
| 66 |
G |
A |
-1.1310 |
|
| 67 |
S |
A |
-1.1676 |
|
| 68 |
G |
A |
-1.4520 |
|
| 69 |
T |
A |
-2.0506 |
|
| 70 |
D |
A |
-2.8544 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.9578 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
S |
A |
-0.8434 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
N |
A |
-2.2758 |
|
| 77 |
S |
A |
-2.2721 |
|
| 78 |
V |
A |
0.0000 |
|
| 79 |
E |
A |
-3.0761 |
|
| 80 |
S |
A |
-2.8688 |
|
| 81 |
E |
A |
-3.1527 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
I |
A |
-2.0852 |
|
| 84 |
A |
A |
0.0000 |
|
| 85 |
D |
A |
-1.1303 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
-0.0006 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.3211 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
N |
A |
-1.2710 |
|
| 92 |
N |
A |
-1.6821 |
|
| 93 |
N |
A |
-1.2440 |
|
| 94 |
W |
A |
0.0893 |
|
| 95 |
P |
A |
-0.2514 |
|
| 96 |
T |
A |
-0.4315 |
|
| 97 |
T |
A |
0.3275 |
|
| 98 |
F |
A |
1.4560 |
|
| 99 |
G |
A |
0.6595 |
|
| 100 |
A |
A |
0.5580 |
|
| 101 |
G |
A |
0.2440 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
-0.5298 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
E |
A |
-1.1883 |
|
| 106 |
L |
A |
0.0000 |
|
| 107 |
K |
A |
-1.7212 |
|
| 108 |
R |
A |
-1.1755 |
|
| 109 |
T |
A |
-0.0946 |
|
| 110 |
V |
A |
0.3676 |
|
| 111 |
A |
A |
-0.0877 |
|
| 112 |
A |
A |
-0.1886 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
-0.1063 |
|
| 115 |
V |
A |
0.0000 |
|
| 116 |
F |
A |
1.3546 |
|
| 117 |
I |
A |
1.3232 |
|
| 118 |
F |
A |
1.5131 |
|
| 119 |
P |
A |
-0.0039 |
|
| 120 |
P |
A |
-0.7486 |
|
| 121 |
S |
A |
-1.8249 |
|
| 122 |
D |
A |
-3.2563 |
|
| 123 |
E |
A |
-3.4599 |
|
| 124 |
Q |
A |
-2.5228 |
|
| 125 |
L |
A |
-2.6355 |
|
| 126 |
K |
A |
-3.0224 |
|
| 127 |
S |
A |
-1.8663 |
|
| 128 |
G |
A |
-1.4204 |
|
| 129 |
T |
A |
-1.1379 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
0.0371 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.7513 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.5444 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.5520 |
|
| 138 |
N |
A |
-1.3181 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
-1.2018 |
|
| 141 |
P |
A |
-1.7394 |
|
| 142 |
R |
A |
-3.1154 |
|
| 143 |
E |
A |
-3.2606 |
|
| 144 |
A |
A |
-2.3552 |
|
| 145 |
K |
A |
-2.3745 |
|
| 146 |
V |
A |
-1.1821 |
|
| 147 |
Q |
A |
-0.8174 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.7929 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-1.9621 |
|
| 152 |
N |
A |
-1.5776 |
|
| 153 |
A |
A |
-0.3477 |
|
| 154 |
L |
A |
0.5728 |
|
| 155 |
Q |
A |
-0.2931 |
|
| 156 |
S |
A |
-0.4233 |
|
| 157 |
G |
A |
-1.0191 |
|
| 158 |
N |
A |
-0.9890 |
|
| 159 |
S |
A |
-1.4170 |
|
| 160 |
Q |
A |
-2.3012 |
|
| 161 |
E |
A |
-2.3432 |
|
| 162 |
S |
A |
-1.3527 |
|
| 163 |
V |
A |
-0.8350 |
|
| 164 |
T |
A |
-1.2904 |
|
| 165 |
E |
A |
-2.5651 |
|
| 166 |
Q |
A |
0.0000 |
|
| 167 |
D |
A |
-2.5178 |
|
| 168 |
S |
A |
-2.9215 |
|
| 169 |
K |
A |
-3.0330 |
|
| 170 |
D |
A |
-2.2114 |
|
| 171 |
S |
A |
0.0000 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
0.0000 |
|
| 174 |
S |
A |
-1.0140 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.4827 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.6094 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.5255 |
|
| 181 |
L |
A |
-0.7128 |
|
| 182 |
S |
A |
-1.0694 |
|
| 183 |
K |
A |
-2.0814 |
|
| 184 |
A |
A |
-1.9171 |
|
| 185 |
D |
A |
-2.6803 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.7251 |
|
| 188 |
K |
A |
-3.7756 |
|
| 189 |
H |
A |
-3.1587 |
|
| 190 |
K |
A |
-3.1758 |
|
| 191 |
V |
A |
-1.4800 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
0.0000 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-1.0122 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.2407 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.5718 |
|
| 200 |
G |
A |
-0.3916 |
|
| 201 |
L |
A |
-0.1900 |
|
| 202 |
S |
A |
-0.4271 |
|
| 203 |
S |
A |
-0.3802 |
|
| 204 |
P |
A |
-0.5588 |
|
| 205 |
V |
A |
0.0278 |
|
| 206 |
T |
A |
-0.3055 |
|
| 207 |
K |
A |
-0.2077 |
|
| 208 |
S |
A |
-0.3037 |
|
| 209 |
F |
A |
-0.5234 |
|
| 210 |
N |
A |
-1.6279 |
|
| 211 |
R |
A |
-2.3745 |
|
| 212 |
G |
A |
-1.2272 |
|
| 213 |
A |
A |
-0.7146 |
|