Project name: 10-8pig

Chain sequence(s)	H: QVQLVQSGAEVKKPGASVKVSCKASGYTFTDYSVHWVRQAPGQGLEWMGVINTYSGNTDYAQKFQGRVTMTRDTSTSTVYMELSSLRSEDTAVYYCARGYGSWFAYWGQGTTLT; L: DIQMTQSPSSLSASVGDRVTITCSVQSSISSSGLHWYQQKPEKAPKSLIFGTSNRASGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQHWSSYPLTFGAGTKLEIKRTV
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.171
• Maximal score value: 1.7596
• Average score: -0.2652
• Total score value: -59.4019

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	L	-1.7511
2	I	L	-0.3357
3	Q	L	-1.1600
4	M	L	0.0000
5	T	L	-0.0935
6	Q	L	-0.1742
7	S	L	-0.2639
8	P	L	-0.1994
9	S	L	-0.2689
10	S	L	-0.4352
11	L	L	0.1302
12	S	L	-0.1736
13	A	L	-0.0403
14	S	L	-0.0562
15	V	L	1.0236
16	G	L	-0.1990
17	D	L	-1.2600
18	R	L	-2.0173
19	V	L	0.0000
20	T	L	-0.0726
21	I	L	0.0000
22	T	L	-0.0276
23	C	L	0.0000
24	S	L	-0.2583
25	V	L	0.0000
26	Q	L	-1.2375
27	S	L	-0.4728
28	S	L	-0.2251
29	I	L	0.1299
30	S	L	-0.2101
31	S	L	-0.1664
32	S	L	-0.2279
33	G	L	0.0000
34	L	L	0.0000
35	H	L	0.0000
36	W	L	0.0000
37	Y	L	0.0000
38	Q	L	0.0000
39	Q	L	-0.2007
40	K	L	-0.4674
41	P	L	-0.6147
42	E	L	-2.1710
43	K	L	-2.0324
44	A	L	-0.2955
45	P	L	0.0000
46	K	L	-1.2478
47	S	L	-0.2519
48	L	L	0.0000
49	I	L	0.0000
50	F	L	0.5347
51	G	L	0.0127
52	T	L	0.0000
53	S	L	-0.3501
54	N	L	-1.4854
55	R	L	-1.4744
56	A	L	-0.2660
57	S	L	-0.2966
58	G	L	-0.4657
59	V	L	0.1092
60	P	L	-0.1142
61	S	L	-0.3022
62	R	L	-0.4134
63	F	L	0.0000
64	S	L	-0.0638
65	G	L	-0.1181
66	S	L	-0.2524
67	G	L	-0.3222
68	S	L	-0.2812
69	G	L	-0.1443
70	T	L	-0.3821
71	D	L	-1.7975
72	F	L	0.0000
73	T	L	-0.0162
74	L	L	0.0000
75	T	L	-0.0229
76	I	L	0.0000
77	S	L	-0.3491
78	S	L	-0.2332
79	L	L	0.0000
80	Q	L	-0.3620
81	P	L	-0.6625
82	E	L	-1.8659
83	D	L	0.0000
84	F	L	1.1000
85	A	L	0.0000
86	T	L	0.0000
87	Y	L	0.0000
88	Y	L	0.1407
89	C	L	0.0000
90	Q	L	0.0000
91	H	L	0.0000
92	W	L	0.3484
93	S	L	-0.0625
94	S	L	0.0082
95	Y	L	1.2663
96	P	L	0.3201
97	L	L	0.0000
98	T	L	0.0216
99	F	L	0.1926
100	G	L	0.0000
101	A	L	0.0585
102	G	L	0.0000
103	T	L	0.0000
104	K	L	-1.7279
105	L	L	0.0000
106	E	L	-1.1168
107	I	L	-0.2483
108	K	L	-1.9923
109	R	L	-2.1691
110	T	L	-0.0808
111	V	L	1.7596
112	Q	H	-1.1613
113	V	H	-0.2860
114	Q	H	-0.9158
115	L	H	0.0000
116	V	H	1.6916
117	Q	H	0.0000
118	S	H	-0.1473
119	G	H	-0.4668
120	A	H	-0.2136
121	E	H	-0.6306
122	V	H	1.5061
123	K	H	-0.3917
124	K	H	-1.8224
125	P	H	-0.7969
126	G	H	-0.5384
127	A	H	-0.1020
128	S	H	-0.1511
129	V	H	0.0000
130	K	H	-1.8026
131	V	H	0.0000
132	S	H	-0.0141
133	C	H	0.0000
134	K	H	-0.8326
135	A	H	0.0000
136	S	H	-0.2994
137	G	H	-0.4334
138	Y	H	0.1078
139	T	H	-0.0328
140	F	H	0.0000
141	T	H	-0.1555
142	D	H	-1.7147
143	Y	H	0.0892
144	S	H	-0.0373
145	V	H	0.0000
146	H	H	0.0000
147	W	H	0.0000
148	V	H	0.0000
149	R	H	0.0000
150	Q	H	-0.5088
151	A	H	-0.1331
152	P	H	-0.3395
153	G	H	-0.5132
155	G	H	-0.3188
156	L	H	0.0000
157	E	H	-0.2938
158	W	H	0.0000
159	M	H	0.0000
160	G	H	0.0000
161	V	H	0.1867
162	I	H	0.0000
163	N	H	-0.6615
164	T	H	0.0000
165	Y	H	1.2844
166	S	H	0.0710
167	G	H	-0.3660
168	N	H	-1.2959
169	T	H	-0.5856
170	D	H	-1.7337
171	Y	H	-0.0098
172	A	H	0.0000
173	Q	H	-1.6365
174	K	H	-1.9200
175	F	H	0.0000
176	Q	H	-1.4099
177	G	H	-0.7268
178	R	H	-0.3174
179	V	H	0.0000
180	T	H	-0.0549
181	M	H	0.0000
182	T	H	-0.1442
183	R	H	-0.7730
184	D	H	-0.9223
185	T	H	-0.2484
186	S	H	-0.2282
187	T	H	-0.0780
188	S	H	-0.0631
189	T	H	0.0000
190	V	H	0.0000
191	Y	H	0.2156
192	M	H	0.0000
193	E	H	-0.9410
194	L	H	0.0000
195	S	H	-0.1602
196	S	H	-0.2539
197	L	H	0.0000
198	R	H	-1.4294
199	S	H	-0.7839
200	E	H	-1.7846
201	D	H	0.0000
202	T	H	-0.0361
203	A	H	0.0000
204	V	H	0.3091
205	Y	H	0.0000
206	Y	H	0.0000
207	C	H	0.0000
208	A	H	0.0000
209	R	H	-0.2046
210	G	H	0.0000
211	Y	H	1.2722
212	G	H	-0.0232
213	S	H	-0.1837
214	W	H	0.1053
215	F	H	0.0000
216	A	H	0.0633
217	Y	H	0.2864
218	W	H	0.0000
219	G	H	-0.3133
220	Q	H	-1.2183
221	G	H	-0.2743
222	T	H	0.0000
223	T	H	0.0175
224	L	H	0.0000
225	T	H	0.1179