Project name: 4g6k:L
Status: done
submitted: 2019-03-20 20:16:40, status changed: 2019-03-20 20:28:19
Settings
|
Chain sequence(s)
|
L: DIQMTQSTSSLSASVGDRVTITCRASQDISNYLSWYQQKPGKAVKLLIYYTSKLHSGVPSRFSGSGSGTDYTLTISSLQQEDFATYFCLQGKMLPWTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.8144
-
Maximal score value
-
1.4726
-
Average score
-
-0.7793
-
Total score value
-
-165.2186
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.7542 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
Q |
L |
-1.7593 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-1.1735 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.7637 |
|
| 8 |
T |
L |
-0.6065 |
|
| 9 |
S |
L |
-0.9058 |
|
| 10 |
S |
L |
-0.8342 |
|
| 11 |
L |
L |
-0.3860 |
|
| 12 |
S |
L |
-0.8357 |
|
| 13 |
A |
L |
0.0000 |
|
| 14 |
S |
L |
-1.2741 |
|
| 15 |
V |
L |
-0.8277 |
|
| 16 |
G |
L |
-1.2270 |
|
| 17 |
D |
L |
-2.1162 |
|
| 18 |
R |
L |
-2.4552 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6560 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.7493 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.8499 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-2.1948 |
|
| 27 |
Q |
L |
-2.6866 |
|
| 28 |
D |
L |
-2.7746 |
|
| 29 |
I |
L |
0.0000 |
|
| 30 |
S |
L |
-0.8436 |
|
| 31 |
N |
L |
-0.4052 |
|
| 32 |
Y |
L |
0.7374 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
S |
L |
0.8000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
0.3394 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.1546 |
|
| 39 |
K |
L |
-1.8696 |
|
| 40 |
P |
L |
-1.5244 |
|
| 41 |
G |
L |
-1.5653 |
|
| 42 |
K |
L |
-2.0526 |
|
| 43 |
A |
L |
-0.7730 |
|
| 44 |
V |
L |
0.0316 |
|
| 45 |
K |
L |
-1.1129 |
|
| 46 |
L |
L |
-0.1198 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
0.7019 |
|
| 50 |
Y |
L |
1.2129 |
|
| 51 |
T |
L |
0.0000 |
|
| 52 |
S |
L |
-0.5470 |
|
| 53 |
K |
L |
-0.9057 |
|
| 54 |
L |
L |
-0.1938 |
|
| 55 |
H |
L |
-0.7565 |
|
| 56 |
S |
L |
-0.6181 |
|
| 57 |
G |
L |
-0.6002 |
|
| 58 |
V |
L |
0.0000 |
|
| 59 |
P |
L |
-0.4385 |
|
| 60 |
S |
L |
-0.4456 |
|
| 61 |
R |
L |
-0.8184 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.5500 |
|
| 64 |
G |
L |
-0.3288 |
|
| 65 |
S |
L |
-0.7048 |
|
| 66 |
G |
L |
-1.0918 |
|
| 67 |
S |
L |
-1.0461 |
|
| 68 |
G |
L |
-1.7434 |
|
| 69 |
T |
L |
-2.2425 |
|
| 70 |
D |
L |
-2.2887 |
|
| 71 |
Y |
L |
0.0000 |
|
| 72 |
T |
L |
-0.7187 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.6265 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.3988 |
|
| 77 |
S |
L |
-1.3119 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-1.2230 |
|
| 80 |
Q |
L |
-2.2646 |
|
| 81 |
E |
L |
-2.1685 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
0.0000 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
-1.0596 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
F |
L |
0.3789 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
L |
L |
1.1228 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
G |
L |
0.6117 |
|
| 92 |
K |
L |
-0.4846 |
|
| 93 |
M |
L |
0.6044 |
|
| 94 |
L |
L |
1.4317 |
|
| 95 |
P |
L |
0.9714 |
|
| 96 |
W |
L |
1.4726 |
|
| 97 |
T |
L |
0.8149 |
|
| 98 |
F |
L |
1.4308 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
Q |
L |
-0.9804 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-2.0087 |
|
| 104 |
L |
L |
0.0000 |
|
| 105 |
E |
L |
-1.4043 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.6331 |
|
| 108 |
R |
L |
-1.0774 |
|
| 109 |
T |
L |
-0.2007 |
|
| 110 |
V |
L |
0.1204 |
|
| 111 |
A |
L |
-0.0209 |
|
| 112 |
A |
L |
-0.2403 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1209 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.1644 |
|
| 117 |
I |
L |
1.1301 |
|
| 118 |
F |
L |
1.3067 |
|
| 119 |
P |
L |
-0.0969 |
|
| 120 |
P |
L |
0.0000 |
|
| 121 |
S |
L |
-1.8016 |
|
| 122 |
D |
L |
-3.2166 |
|
| 123 |
E |
L |
-3.3846 |
|
| 124 |
Q |
L |
-2.4789 |
|
| 125 |
L |
L |
-2.5272 |
|
| 126 |
K |
L |
-3.0079 |
|
| 127 |
S |
L |
-1.8717 |
|
| 128 |
G |
L |
-1.3110 |
|
| 129 |
T |
L |
-1.0020 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0034 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.6593 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.6058 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.5398 |
|
| 138 |
N |
L |
-1.0914 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.7534 |
|
| 142 |
R |
L |
-2.7195 |
|
| 143 |
E |
L |
-3.0606 |
|
| 144 |
A |
L |
-2.2575 |
|
| 145 |
K |
L |
-2.2256 |
|
| 146 |
V |
L |
0.0000 |
|
| 147 |
Q |
L |
-0.8799 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.8254 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-2.1132 |
|
| 152 |
N |
L |
-1.4989 |
|
| 153 |
A |
L |
-0.5013 |
|
| 154 |
L |
L |
0.2147 |
|
| 155 |
Q |
L |
-0.5865 |
|
| 156 |
S |
L |
-0.8347 |
|
| 157 |
G |
L |
-1.4651 |
|
| 158 |
N |
L |
-1.9054 |
|
| 159 |
S |
L |
-1.9324 |
|
| 160 |
Q |
L |
-2.4980 |
|
| 161 |
E |
L |
-2.3964 |
|
| 162 |
S |
L |
-1.1082 |
|
| 163 |
V |
L |
-0.8829 |
|
| 164 |
T |
L |
-1.1342 |
|
| 165 |
E |
L |
-2.2926 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.3580 |
|
| 168 |
S |
L |
-2.3247 |
|
| 169 |
K |
L |
-2.6144 |
|
| 170 |
D |
L |
-2.0046 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.9205 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.5298 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.7963 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.6933 |
|
| 181 |
L |
L |
-0.7415 |
|
| 182 |
S |
L |
-1.1819 |
|
| 183 |
K |
L |
-2.2698 |
|
| 184 |
A |
L |
-2.0271 |
|
| 185 |
D |
L |
-2.8265 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.8144 |
|
| 188 |
K |
L |
-3.7447 |
|
| 189 |
H |
L |
-3.2219 |
|
| 190 |
K |
L |
-3.2458 |
|
| 191 |
V |
L |
-1.7161 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.9003 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.2488 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.7343 |
|
| 200 |
G |
L |
-0.4582 |
|
| 201 |
L |
L |
-0.2152 |
|
| 202 |
S |
L |
-0.4395 |
|
| 203 |
S |
L |
-0.4105 |
|
| 204 |
P |
L |
-0.5457 |
|
| 205 |
V |
L |
-0.0481 |
|
| 206 |
T |
L |
-0.4508 |
|
| 207 |
K |
L |
-0.3932 |
|
| 208 |
S |
L |
-0.5166 |
|
| 209 |
F |
L |
-0.8644 |
|
| 210 |
N |
L |
-2.2060 |
|
| 211 |
R |
L |
-2.2945 |
|
| 212 |
G |
L |
-1.6130 |
|