Project name: 4g6k:H

Chain sequence(s)	H: QVQLQESGPGLVKPSQTLSLTCSFSGFSLSTSGMGVGWIRQPSGKGLEWLAHIWWDGDESYNPSLKSRLTISKDTSKNQVSLKITSVTAADTAVYFCARNRYDPPWFVDWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.1375
• Maximal score value: 2.4242
• Average score: -0.5495
• Total score value: -120.8943

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.5010
2	V	H	-0.8572
3	Q	H	-1.7766
4	L	H	0.0000
5	Q	H	-1.3633
6	E	H	0.0000
7	S	H	-0.5430
8	G	H	-0.4386
9	P	H	-0.3597
10	G	H	-0.3139
11	L	H	-0.2353
12	V	H	0.0000
13	K	H	-1.8071
14	P	H	-1.2750
15	S	H	-1.2188
16	Q	H	-1.6454
17	T	H	-1.1479
18	L	H	0.0000
19	S	H	-0.8264
20	L	H	0.0000
21	T	H	-0.6112
22	C	H	0.0000
23	S	H	-1.3620
24	F	H	0.0000
25	S	H	-1.1700
26	G	H	-0.9708
27	F	H	-0.4457
28	S	H	-0.4578
29	L	H	0.0000
30	S	H	-0.7020
31	T	H	-0.4398
32	S	H	-0.3923
33	G	H	0.0000
34	M	H	0.0000
35	G	H	0.0000
36	V	H	0.0000
37	G	H	0.0000
38	W	H	0.0000
39	I	H	0.0000
40	R	H	0.0000
41	Q	H	-0.5213
42	P	H	-0.8137
43	S	H	-1.0690
44	G	H	-1.5622
45	K	H	-2.0880
46	G	H	-0.9460
47	L	H	0.6318
48	E	H	-0.1980
49	W	H	0.3817
50	L	H	0.0000
51	A	H	0.0000
52	H	H	0.0000
53	I	H	0.0000
54	W	H	-1.5812
55	W	H	-1.2211
56	D	H	-2.4259
57	G	H	-2.2746
58	D	H	-3.1375
59	E	H	-2.7579
60	S	H	-1.1677
61	Y	H	-0.4211
62	N	H	-0.5322
63	P	H	-1.0486
64	S	H	-0.9617
65	L	H	0.0000
66	K	H	-2.0086
67	S	H	-1.2194
68	R	H	-1.1322
69	L	H	-0.6988
70	T	H	-0.6206
71	I	H	0.0000
72	S	H	-1.3474
73	K	H	-1.7348
74	D	H	-2.8800
75	T	H	-1.8911
76	S	H	-1.8413
77	K	H	-2.7370
78	N	H	-2.0327
79	Q	H	-2.0300
80	V	H	0.0000
81	S	H	-0.8674
82	L	H	0.0000
83	K	H	-1.0106
84	I	H	0.0000
85	T	H	-0.8362
86	S	H	-0.9615
87	V	H	0.0000
88	T	H	-0.5426
89	A	H	-0.1945
90	A	H	0.0447
91	D	H	0.0000
92	T	H	0.0723
93	A	H	0.0000
94	V	H	0.3383
95	Y	H	0.0000
96	F	H	0.2407
97	C	H	0.0000
98	A	H	0.0000
99	R	H	0.3442
100	N	H	0.0000
101	R	H	-0.1708
102	Y	H	0.0846
103	D	H	-1.3233
104	P	H	-0.8044
105	P	H	0.2127
106	W	H	1.4726
107	F	H	1.6142
108	V	H	2.1118
109	D	H	0.7043
110	W	H	0.3590
111	G	H	-0.8590
112	Q	H	-1.2412
113	G	H	0.0000
114	T	H	-0.1749
115	L	H	0.3023
116	V	H	0.0000
117	T	H	0.0000
118	V	H	0.0000
119	S	H	-0.6384
120	S	H	-0.7593
121	A	H	-0.4875
122	S	H	-0.6015
123	T	H	-0.7238
124	K	H	-1.1672
125	G	H	-1.4247
126	P	H	0.0000
127	S	H	-0.2924
128	V	H	0.0000
129	F	H	0.7872
130	P	H	0.0202
131	L	H	0.5481
132	A	H	-0.5070
133	P	H	0.0000
134	S	H	-1.0760
135	S	H	-1.2413
136	K	H	-1.9845
137	S	H	-1.2242
138	T	H	-1.0325
139	S	H	-1.0621
140	G	H	-0.8010
141	G	H	-0.6304
142	T	H	-0.4399
143	A	H	0.0000
144	A	H	0.0866
145	L	H	0.0000
146	G	H	0.0000
147	C	H	0.0000
148	L	H	0.7367
149	V	H	0.0000
150	K	H	-0.2339
151	D	H	-0.6364
152	Y	H	0.0000
153	F	H	0.0000
154	P	H	0.0000
155	E	H	-0.3191
156	P	H	-0.6030
157	V	H	-0.6207
158	T	H	-0.5720
159	V	H	-0.2371
160	S	H	-0.3571
161	W	H	0.0000
162	N	H	-0.8312
163	S	H	-0.6723
164	G	H	-0.5680
165	A	H	-0.2462
166	L	H	-0.0396
167	T	H	-0.2904
168	S	H	-0.3583
169	G	H	-0.4485
170	V	H	0.0128
171	H	H	-0.4394
172	T	H	0.0973
173	F	H	0.6766
174	P	H	0.5327
175	A	H	1.1820
176	V	H	2.4242
177	L	H	2.0498
178	Q	H	0.6528
179	S	H	0.0540
180	S	H	-0.2475
181	G	H	0.1684
182	L	H	0.3010
183	Y	H	0.7960
184	S	H	0.0000
185	L	H	0.0000
186	S	H	0.5762
187	S	H	0.0000
188	V	H	0.3772
189	V	H	0.0000
190	T	H	-0.2058
191	V	H	0.0000
192	P	H	-0.5637
193	S	H	-0.8302
194	S	H	-0.7145
195	S	H	-0.6754
196	L	H	-0.8953
197	G	H	-1.0705
198	T	H	-0.7052
199	Q	H	-1.1865
200	T	H	-1.1601
201	Y	H	0.0000
202	I	H	-1.5677
203	C	H	0.0000
204	N	H	-1.6333
205	V	H	0.0000
206	N	H	-1.9593
207	H	H	0.0000
208	K	H	-2.7064
209	P	H	-1.5957
210	S	H	-1.8151
211	N	H	-2.6144
212	T	H	-2.0373
213	K	H	-2.8037
214	V	H	-1.8198
215	D	H	-2.7046
216	K	H	-2.4995
217	R	H	-2.8265
218	V	H	0.0000
219	E	H	-2.5525
220	P	H	-1.1831