Project name: 4nyl:H

Chain sequence(s)	H: EVQLVESGGGLVQPGRSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSAITWNSGHIDYADSVEGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAKVSYLSTASSLDYWGQGTLVTVSSASTKGPSVFPLAPGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKV
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0723
• Maximal score value: 2.4047
• Average score: -0.5925
• Total score value: -125.6104

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.5324
2	V	H	-0.0975
3	Q	H	-0.4932
4	L	H	0.0000
5	V	H	0.7417
6	E	H	0.0000
7	S	H	-0.3461
8	G	H	-0.9552
9	G	H	-0.5458
10	G	H	-0.3107
11	L	H	0.0243
12	V	H	0.0000
13	Q	H	-1.8429
14	P	H	-1.9526
15	G	H	-2.2599
16	R	H	-2.8402
17	S	H	-2.3446
18	L	H	-1.7294
19	R	H	-2.3421
20	L	H	0.0000
21	S	H	-0.5381
22	C	H	0.0000
23	A	H	-0.2138
24	A	H	0.0000
25	S	H	-0.3976
26	G	H	-0.6021
27	F	H	-0.5142
28	T	H	-1.1354
29	F	H	0.0000
30	D	H	-3.0723
31	D	H	-2.0870
32	Y	H	-0.5524
33	A	H	0.0000
34	M	H	0.0000
35	H	H	-0.0922
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.4536
40	A	H	-1.1513
41	P	H	-1.1396
42	G	H	-1.4122
43	K	H	-2.1065
44	G	H	-0.9909
45	L	H	0.5151
46	E	H	-0.3509
47	W	H	0.2996
48	V	H	0.0000
49	S	H	0.0000
50	A	H	0.0000
51	I	H	0.0000
52	T	H	-0.9252
53	W	H	-1.2465
54	N	H	-2.0403
55	S	H	-1.0998
56	G	H	-1.1277
57	H	H	-1.2526
58	I	H	-0.4311
59	D	H	-1.7858
60	Y	H	-1.4439
61	A	H	-1.7220
62	D	H	-2.6611
63	S	H	-1.6079
64	V	H	0.0000
65	E	H	-2.9564
66	G	H	-1.8650
67	R	H	-1.5388
68	F	H	0.0000
69	T	H	-1.0723
70	I	H	0.0000
71	S	H	-0.4576
72	R	H	-1.2736
73	D	H	-2.0053
74	N	H	-2.3485
75	A	H	-1.6126
76	K	H	-2.4234
77	N	H	-2.0180
78	S	H	0.0000
79	L	H	0.0000
80	Y	H	-0.7494
81	L	H	0.0000
82	Q	H	-1.7561
83	M	H	0.0000
84	N	H	-2.2349
85	S	H	-1.9529
86	L	H	0.0000
87	R	H	-3.0524
88	A	H	-1.9505
89	E	H	-2.4153
90	D	H	0.0000
91	T	H	-0.9831
92	A	H	0.0000
93	V	H	0.4155
94	Y	H	0.0000
95	Y	H	0.3852
96	C	H	0.0000
97	A	H	0.0000
98	K	H	0.0000
99	V	H	0.0000
100	S	H	0.1494
101	Y	H	1.2505
102	L	H	1.2267
103	S	H	0.6049
104	T	H	0.3225
105	A	H	0.3024
106	S	H	0.1853
107	S	H	-0.3541
108	L	H	-0.4073
109	D	H	-1.3100
110	Y	H	-0.2917
111	W	H	0.1632
112	G	H	0.0000
113	Q	H	-0.7892
114	G	H	0.0000
115	T	H	-0.0289
116	L	H	0.0760
117	V	H	0.0000
118	T	H	-0.4915
119	V	H	0.0000
120	S	H	-0.9085
121	S	H	-0.5672
122	A	H	-0.5005
123	S	H	-0.7438
124	T	H	-1.1298
125	K	H	-2.0432
126	G	H	-1.9969
127	P	H	-1.0102
128	S	H	-0.4956
129	V	H	0.0000
130	F	H	0.8159
131	P	H	0.4515
132	L	H	0.9557
133	A	H	0.4463
134	P	H	0.0086
142	G	H	-0.6563
143	T	H	-0.4972
144	A	H	-0.2685
145	A	H	0.0582
146	L	H	0.0000
147	G	H	0.0000
148	C	H	0.0000
149	L	H	0.4632
150	V	H	0.0000
151	K	H	-0.5356
152	D	H	-0.8541
153	Y	H	0.0000
154	F	H	0.0000
155	P	H	0.0000
156	E	H	-0.4468
157	P	H	-0.7086
158	V	H	-0.7510
159	T	H	-0.4997
160	V	H	0.0000
161	S	H	-0.4941
162	W	H	0.0000
163	N	H	-0.8099
164	S	H	-0.7221
165	G	H	-0.6246
166	A	H	-0.2560
167	L	H	-0.0089
168	T	H	-0.2318
169	S	H	-0.3200
170	G	H	-0.3693
171	V	H	0.0565
172	H	H	-0.5528
173	T	H	0.0099
174	F	H	0.7206
175	P	H	0.6175
176	A	H	1.2009
177	V	H	2.4047
178	L	H	2.0999
179	Q	H	0.5331
180	S	H	0.0017
181	S	H	-0.3014
182	G	H	0.1144
183	L	H	0.0360
184	Y	H	0.7161
185	S	H	0.0000
186	L	H	0.0000
187	S	H	0.4666
188	S	H	0.0000
189	V	H	0.3333
190	V	H	0.0000
191	T	H	-0.2278
192	V	H	0.0000
193	P	H	-0.4620
194	S	H	-0.4811
195	S	H	-0.5301
196	S	H	-0.4463
197	L	H	-0.0890
198	G	H	-0.5576
199	T	H	-0.6941
200	Q	H	-1.1422
201	T	H	-0.7182
202	Y	H	0.0000
203	I	H	-1.0169
204	C	H	0.0000
205	N	H	-1.7949
206	V	H	0.0000
207	N	H	-2.0604
208	H	H	0.0000
209	K	H	-2.8162
210	P	H	-1.7237
211	S	H	-2.0717
212	N	H	-2.7313
213	T	H	-2.0323
214	K	H	-2.7910
215	V	H	-1.8841
216	D	H	-2.8412
217	K	H	-2.0547
218	K	H	-2.0047
219	V	H	-0.2220