Project name: 5vh4:L
Status: done
submitted: 2019-03-20 20:37:28, status changed: 2019-03-20 20:48:02
Settings
|
Chain sequence(s)
|
L: DILLTQSPAILSVSPGERVSFSCRASQFVGSSIHWYQQRTNGSSPRLLIKYASESMSGIPSRFSGSGSGTDDFTLSINTVESEEDIADYYCQQSHSWPFTFGSGTNLEVKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.8557
-
Maximal score value
-
2.0917
-
Average score
-
-0.7533
-
Total score value
-
-160.4581
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.1789 |
|
| 2 |
I |
L |
0.3594 |
|
| 3 |
L |
L |
0.9860 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
T |
L |
-0.4266 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.3006 |
|
| 8 |
P |
L |
0.2775 |
|
| 9 |
A |
L |
0.6363 |
|
| 10 |
I |
L |
1.7083 |
|
| 11 |
L |
L |
0.9072 |
|
| 12 |
S |
L |
0.1112 |
|
| 13 |
V |
L |
-1.1705 |
|
| 14 |
S |
L |
-1.6163 |
|
| 15 |
P |
L |
-1.9698 |
|
| 16 |
G |
L |
-2.2462 |
|
| 17 |
E |
L |
-3.1360 |
|
| 18 |
R |
L |
-3.2956 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
S |
L |
-0.7346 |
|
| 21 |
F |
L |
0.0000 |
|
| 22 |
S |
L |
-1.0216 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.3727 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-0.6838 |
|
| 27 |
Q |
L |
-0.7737 |
|
| 28 |
F |
L |
0.6959 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
G |
L |
0.0134 |
|
| 31 |
S |
L |
-0.0480 |
|
| 32 |
S |
L |
0.1814 |
|
| 33 |
I |
L |
0.0000 |
|
| 34 |
H |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.0857 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.4119 |
|
| 39 |
R |
L |
-2.1140 |
|
| 40 |
T |
L |
-1.8074 |
|
| 41 |
N |
L |
-1.9346 |
|
| 42 |
G |
L |
-1.4892 |
|
| 43 |
S |
L |
-1.0762 |
|
| 44 |
P |
L |
-0.9833 |
|
| 45 |
R |
L |
-0.7538 |
|
| 46 |
L |
L |
-0.1001 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
K |
L |
-0.6572 |
|
| 50 |
Y |
L |
0.1835 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
-1.0591 |
|
| 53 |
E |
L |
-1.8806 |
|
| 54 |
S |
L |
-1.0683 |
|
| 55 |
M |
L |
-0.5385 |
|
| 56 |
S |
L |
-0.4474 |
|
| 57 |
G |
L |
-0.4437 |
|
| 58 |
I |
L |
-0.2092 |
|
| 59 |
P |
L |
-0.3567 |
|
| 60 |
S |
L |
-0.6980 |
|
| 61 |
R |
L |
-1.2580 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-1.0363 |
|
| 64 |
G |
L |
-0.6991 |
|
| 65 |
S |
L |
-0.8027 |
|
| 66 |
G |
L |
-1.0579 |
|
| 67 |
S |
L |
-0.6858 |
|
| 68 |
G |
L |
-0.4982 |
|
| 69 |
T |
L |
-1.3065 |
|
| 70 |
D |
L |
-2.5979 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.9227 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
S |
L |
-1.0029 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
N |
L |
-2.8501 |
|
| 77 |
T |
L |
-2.4697 |
|
| 78 |
V |
L |
0.0000 |
|
| 79 |
E |
L |
-2.6653 |
|
| 80 |
S |
L |
-2.3471 |
|
| 81 |
E |
L |
-2.3304 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
I |
L |
0.0000 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
D |
L |
-0.7847 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.2896 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
S |
L |
0.5054 |
|
| 92 |
H |
L |
-0.0067 |
|
| 93 |
S |
L |
0.2651 |
|
| 94 |
W |
L |
0.8873 |
|
| 95 |
P |
L |
0.5089 |
|
| 96 |
F |
L |
1.3949 |
|
| 97 |
T |
L |
1.3319 |
|
| 98 |
F |
L |
2.0917 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
S |
L |
0.2405 |
|
| 101 |
G |
L |
0.1472 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
N |
L |
-0.1050 |
|
| 104 |
L |
L |
0.0000 |
|
| 105 |
E |
L |
-0.6126 |
|
| 106 |
V |
L |
0.0000 |
|
| 107 |
K |
L |
-1.3234 |
|
| 108 |
R |
L |
-0.9735 |
|
| 109 |
T |
L |
-0.0010 |
|
| 110 |
V |
L |
0.4498 |
|
| 111 |
A |
L |
-0.1454 |
|
| 112 |
A |
L |
-0.2123 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.0709 |
|
| 115 |
V |
L |
0.4082 |
|
| 116 |
F |
L |
1.3886 |
|
| 117 |
I |
L |
1.3057 |
|
| 118 |
F |
L |
1.4826 |
|
| 119 |
P |
L |
0.0458 |
|
| 120 |
P |
L |
0.0000 |
|
| 121 |
S |
L |
-1.7498 |
|
| 122 |
D |
L |
-3.1720 |
|
| 123 |
E |
L |
-3.3548 |
|
| 124 |
Q |
L |
-2.3341 |
|
| 125 |
L |
L |
-2.3985 |
|
| 126 |
K |
L |
-2.9207 |
|
| 127 |
S |
L |
-1.8202 |
|
| 128 |
G |
L |
-1.3675 |
|
| 129 |
T |
L |
-1.0904 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0809 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7393 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.5227 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.5894 |
|
| 138 |
N |
L |
-1.4163 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.7517 |
|
| 142 |
R |
L |
-3.1486 |
|
| 143 |
E |
L |
-3.2748 |
|
| 144 |
A |
L |
-2.3459 |
|
| 145 |
K |
L |
-2.4028 |
|
| 146 |
V |
L |
-1.0686 |
|
| 147 |
Q |
L |
-0.6838 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.8310 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.9208 |
|
| 152 |
N |
L |
-1.6023 |
|
| 153 |
A |
L |
-0.4266 |
|
| 154 |
L |
L |
0.4008 |
|
| 155 |
Q |
L |
-0.4904 |
|
| 156 |
S |
L |
-0.7719 |
|
| 157 |
G |
L |
-1.4524 |
|
| 158 |
N |
L |
-1.8933 |
|
| 159 |
S |
L |
-1.8478 |
|
| 160 |
Q |
L |
-2.4582 |
|
| 161 |
E |
L |
-2.2511 |
|
| 162 |
S |
L |
-1.2569 |
|
| 163 |
V |
L |
-0.6783 |
|
| 164 |
T |
L |
-1.1547 |
|
| 165 |
E |
L |
-2.3333 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.0991 |
|
| 168 |
S |
L |
-2.3229 |
|
| 169 |
K |
L |
-2.6957 |
|
| 170 |
D |
L |
-2.2273 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.9882 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.4247 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.7318 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.7954 |
|
| 181 |
L |
L |
-0.9674 |
|
| 182 |
S |
L |
-1.1259 |
|
| 183 |
K |
L |
-2.1233 |
|
| 184 |
A |
L |
-2.0149 |
|
| 185 |
D |
L |
-2.9173 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.8511 |
|
| 188 |
K |
L |
-3.8557 |
|
| 189 |
H |
L |
-3.2173 |
|
| 190 |
K |
L |
-3.3065 |
|
| 191 |
V |
L |
-1.4589 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.9648 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.1816 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.7630 |
|
| 200 |
G |
L |
-0.4142 |
|
| 201 |
L |
L |
-0.2279 |
|
| 202 |
S |
L |
-0.4579 |
|
| 203 |
S |
L |
-0.4263 |
|
| 204 |
P |
L |
-0.5633 |
|
| 205 |
V |
L |
-0.0787 |
|
| 206 |
T |
L |
-0.4029 |
|
| 207 |
K |
L |
-0.2977 |
|
| 208 |
S |
L |
-0.2539 |
|
| 209 |
F |
L |
-0.7102 |
|
| 210 |
N |
L |
-1.8337 |
|
| 211 |
R |
L |
-2.5708 |
|
| 212 |
G |
L |
-2.1805 |
|
| 213 |
E |
L |
-2.4395 |
|