Project name: 5tru:L
Status: done
submitted: 2019-03-20 20:36:05, status changed: 2019-03-20 20:49:15
Settings
|
Chain sequence(s)
|
L: EIVLTQSPGTLSLSPGERATLSCRASQSVGSSYLAWYQQKPGQAPRLLIYGAFSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.5877
-
Maximal score value
-
1.805
-
Average score
-
-0.7753
-
Total score value
-
-165.1307
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
E |
L |
-1.3576 |
|
| 2 |
I |
L |
-0.0253 |
|
| 3 |
V |
L |
0.9242 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
T |
L |
-0.6059 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.9220 |
|
| 8 |
P |
L |
-0.5451 |
|
| 9 |
G |
L |
-0.8586 |
|
| 10 |
T |
L |
-0.3873 |
|
| 11 |
L |
L |
-0.2019 |
|
| 12 |
S |
L |
-0.6316 |
|
| 13 |
L |
L |
-1.0164 |
|
| 14 |
S |
L |
-1.6608 |
|
| 15 |
P |
L |
-2.1575 |
|
| 16 |
G |
L |
-2.4773 |
|
| 17 |
E |
L |
-2.9470 |
|
| 18 |
R |
L |
-3.2777 |
|
| 19 |
A |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6668 |
|
| 21 |
L |
L |
0.0000 |
|
| 22 |
S |
L |
-0.8582 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.3982 |
|
| 25 |
A |
L |
-1.1968 |
|
| 26 |
S |
L |
-0.9633 |
|
| 27 |
Q |
L |
-1.7411 |
|
| 28 |
S |
L |
-1.4550 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
G |
L |
-0.6060 |
|
| 31 |
S |
L |
-0.2701 |
|
| 32 |
S |
L |
0.4859 |
|
| 33 |
Y |
L |
1.2414 |
|
| 34 |
L |
L |
0.0000 |
|
| 35 |
A |
L |
0.0000 |
|
| 36 |
W |
L |
0.0000 |
|
| 37 |
Y |
L |
0.0707 |
|
| 38 |
Q |
L |
0.0000 |
|
| 39 |
Q |
L |
-1.5025 |
|
| 40 |
K |
L |
-2.2155 |
|
| 41 |
P |
L |
-1.5903 |
|
| 42 |
G |
L |
-1.4447 |
|
| 43 |
Q |
L |
-2.1408 |
|
| 44 |
A |
L |
-1.3967 |
|
| 45 |
P |
L |
-1.4576 |
|
| 46 |
R |
L |
-1.8959 |
|
| 47 |
L |
L |
-0.2430 |
|
| 48 |
L |
L |
0.0000 |
|
| 49 |
I |
L |
0.0000 |
|
| 50 |
Y |
L |
1.3876 |
|
| 51 |
G |
L |
1.0348 |
|
| 52 |
A |
L |
0.0000 |
|
| 53 |
F |
L |
1.8050 |
|
| 54 |
S |
L |
0.5650 |
|
| 55 |
R |
L |
-0.6500 |
|
| 56 |
A |
L |
-0.2733 |
|
| 57 |
T |
L |
-0.3928 |
|
| 58 |
G |
L |
-0.7678 |
|
| 59 |
I |
L |
-0.7944 |
|
| 60 |
P |
L |
-1.1278 |
|
| 61 |
D |
L |
-2.0154 |
|
| 62 |
R |
L |
0.0000 |
|
| 63 |
F |
L |
0.0000 |
|
| 64 |
S |
L |
-0.2686 |
|
| 65 |
G |
L |
0.5427 |
|
| 66 |
S |
L |
0.0634 |
|
| 67 |
G |
L |
-0.6952 |
|
| 68 |
S |
L |
-0.7523 |
|
| 69 |
G |
L |
-1.1905 |
|
| 70 |
T |
L |
-1.8165 |
|
| 71 |
D |
L |
-2.2077 |
|
| 72 |
F |
L |
0.0000 |
|
| 73 |
T |
L |
-0.4889 |
|
| 74 |
L |
L |
0.0000 |
|
| 75 |
T |
L |
-0.7513 |
|
| 76 |
I |
L |
0.0000 |
|
| 77 |
S |
L |
-2.3044 |
|
| 78 |
R |
L |
-3.3882 |
|
| 79 |
L |
L |
0.0000 |
|
| 80 |
E |
L |
-2.8306 |
|
| 81 |
P |
L |
-1.9634 |
|
| 82 |
E |
L |
-2.4735 |
|
| 83 |
D |
L |
0.0000 |
|
| 84 |
F |
L |
0.0000 |
|
| 85 |
A |
L |
0.0000 |
|
| 86 |
V |
L |
-0.3707 |
|
| 87 |
Y |
L |
0.0000 |
|
| 88 |
Y |
L |
0.0978 |
|
| 89 |
C |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
Q |
L |
0.0000 |
|
| 92 |
Y |
L |
0.9280 |
|
| 93 |
G |
L |
0.0077 |
|
| 94 |
S |
L |
-0.2930 |
|
| 95 |
S |
L |
-0.3058 |
|
| 96 |
P |
L |
0.1362 |
|
| 97 |
W |
L |
1.2242 |
|
| 98 |
T |
L |
1.0912 |
|
| 99 |
F |
L |
1.5956 |
|
| 100 |
G |
L |
0.0840 |
|
| 101 |
Q |
L |
-0.8246 |
|
| 102 |
G |
L |
0.0000 |
|
| 103 |
T |
L |
0.0000 |
|
| 104 |
K |
L |
-0.7461 |
|
| 105 |
V |
L |
0.0000 |
|
| 106 |
E |
L |
0.0000 |
|
| 107 |
I |
L |
-0.7742 |
|
| 108 |
K |
L |
-1.4679 |
|
| 109 |
R |
L |
-1.2499 |
|
| 110 |
T |
L |
-0.3425 |
|
| 111 |
V |
L |
0.1206 |
|
| 112 |
A |
L |
-0.1285 |
|
| 113 |
A |
L |
-0.3132 |
|
| 114 |
P |
L |
0.0000 |
|
| 115 |
S |
L |
-0.0725 |
|
| 116 |
V |
L |
0.0000 |
|
| 117 |
F |
L |
1.4493 |
|
| 118 |
I |
L |
1.2923 |
|
| 119 |
F |
L |
1.4296 |
|
| 120 |
P |
L |
0.0024 |
|
| 121 |
P |
L |
-0.7272 |
|
| 122 |
S |
L |
-1.7548 |
|
| 123 |
D |
L |
-3.1848 |
|
| 124 |
E |
L |
-3.3193 |
|
| 125 |
Q |
L |
-2.3375 |
|
| 126 |
L |
L |
-2.1668 |
|
| 127 |
K |
L |
-2.8707 |
|
| 128 |
S |
L |
-1.8297 |
|
| 129 |
G |
L |
-1.2242 |
|
| 130 |
T |
L |
-0.9541 |
|
| 131 |
A |
L |
0.0000 |
|
| 132 |
S |
L |
0.0449 |
|
| 133 |
V |
L |
0.0000 |
|
| 134 |
V |
L |
0.7361 |
|
| 135 |
C |
L |
0.0000 |
|
| 136 |
L |
L |
0.5920 |
|
| 137 |
L |
L |
0.0000 |
|
| 138 |
N |
L |
-0.5911 |
|
| 139 |
N |
L |
-1.1773 |
|
| 140 |
F |
L |
0.0000 |
|
| 141 |
Y |
L |
0.0000 |
|
| 142 |
P |
L |
-1.6640 |
|
| 143 |
R |
L |
-2.7826 |
|
| 144 |
E |
L |
-3.0609 |
|
| 145 |
A |
L |
-2.2595 |
|
| 146 |
K |
L |
-2.3310 |
|
| 147 |
V |
L |
-1.1079 |
|
| 148 |
Q |
L |
-0.7664 |
|
| 149 |
W |
L |
0.0000 |
|
| 150 |
K |
L |
-0.6387 |
|
| 151 |
V |
L |
0.0000 |
|
| 152 |
D |
L |
-1.8633 |
|
| 153 |
N |
L |
-1.5286 |
|
| 154 |
A |
L |
-0.2693 |
|
| 155 |
L |
L |
0.6315 |
|
| 156 |
Q |
L |
-0.1483 |
|
| 157 |
S |
L |
-0.4461 |
|
| 158 |
G |
L |
-1.0346 |
|
| 159 |
N |
L |
-0.9919 |
|
| 160 |
S |
L |
-1.4911 |
|
| 161 |
Q |
L |
-2.3231 |
|
| 162 |
E |
L |
-2.3369 |
|
| 163 |
S |
L |
-1.1370 |
|
| 164 |
V |
L |
-0.7227 |
|
| 165 |
T |
L |
-1.1608 |
|
| 166 |
E |
L |
-2.2316 |
|
| 167 |
Q |
L |
-2.0215 |
|
| 168 |
D |
L |
-2.3023 |
|
| 169 |
S |
L |
-1.9931 |
|
| 170 |
K |
L |
-2.5410 |
|
| 171 |
D |
L |
-2.2585 |
|
| 172 |
S |
L |
-1.9894 |
|
| 173 |
T |
L |
0.0000 |
|
| 174 |
Y |
L |
0.0000 |
|
| 175 |
S |
L |
-0.9119 |
|
| 176 |
L |
L |
0.0000 |
|
| 177 |
S |
L |
-0.4423 |
|
| 178 |
S |
L |
0.0000 |
|
| 179 |
T |
L |
-0.5743 |
|
| 180 |
L |
L |
0.0000 |
|
| 181 |
T |
L |
-0.6141 |
|
| 182 |
L |
L |
-0.8436 |
|
| 183 |
S |
L |
-1.1813 |
|
| 184 |
K |
L |
-2.1042 |
|
| 185 |
A |
L |
-1.9807 |
|
| 186 |
D |
L |
-3.0253 |
|
| 187 |
Y |
L |
0.0000 |
|
| 188 |
E |
L |
-3.5061 |
|
| 189 |
K |
L |
-3.5877 |
|
| 190 |
H |
L |
-3.0922 |
|
| 191 |
K |
L |
-3.1165 |
|
| 192 |
V |
L |
-1.5511 |
|
| 193 |
Y |
L |
0.0000 |
|
| 194 |
A |
L |
0.0000 |
|
| 195 |
C |
L |
0.0000 |
|
| 196 |
E |
L |
-0.9026 |
|
| 197 |
V |
L |
0.0000 |
|
| 198 |
T |
L |
-1.2897 |
|
| 199 |
H |
L |
0.0000 |
|
| 200 |
Q |
L |
-1.6121 |
|
| 201 |
G |
L |
-0.5741 |
|
| 202 |
L |
L |
-0.3500 |
|
| 203 |
S |
L |
-0.4976 |
|
| 204 |
S |
L |
-0.4759 |
|
| 205 |
P |
L |
-0.6213 |
|
| 206 |
V |
L |
-0.0930 |
|
| 207 |
T |
L |
-0.3912 |
|
| 208 |
K |
L |
-0.2206 |
|
| 209 |
S |
L |
-0.3022 |
|
| 210 |
F |
L |
-0.7182 |
|
| 211 |
N |
L |
-1.9874 |
|
| 212 |
R |
L |
-2.1353 |
|
| 213 |
G |
L |
-1.3167 |
|